Author Will, Cindy L.

• 2003 | Journal Article | Research Paper
  ​ ​Molecular Architecture of the Multiprotein Splicing Factor SF3b​
  Golas, M. M.; Sander, B.; Will, C. L.; Lührmann, R.   & Stark, H. ​ (2003) 
  Science, 300(5621) pp. 980​-984​.​ DOI: https://doi.org/10.1126/science.1084155 
  ​Details  DOI 

• 2005 | Journal Article
  ​ ​Major Conformational Change in the Complex SF3b upon Integration into the Spliceosomal U11/U12 di-snRNP as Revealed by Electron Cryomicroscopy​
  Golas, M. M.; Sander, B.; Will, C. L.; Lührmann, R.   & Stark, H. ​ (2005) 
  Molecular Cell, 17(6) pp. 869​-883​.​ DOI: https://doi.org/10.1016/j.molcel.2005.02.016 
  ​Details  DOI 

• 2006 | Journal Article
  ​ ​Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions​
  Deckert, J.; Hartmuth, K.; Boehringer, D.; Behzadnia, N.; Will, C. L.; Kastner, B. & Stark, H.  et al.​ (2006) 
  Molecular and Cellular Biology, 26(14) pp. 5528​-5543​.​ DOI: https://doi.org/10.1128/MCB.00582-06 
  ​Details  DOI 

• 2007 | Journal Article
  ​ ​Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes​
  Behzadnia, N.; Golas, M. M.; Hartmuth, K.; Sander, B.; Kastner, B.; Deckert, J. & Dube, P. et al.​ (2007) 
  The EMBO Journal, 26(6) pp. 1737​-1748​.​ DOI: https://doi.org/10.1038/sj.emboj.7601631 
  ​Details  DOI 

• 2012 | Journal Article
  ​ ​The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA​
  Mozaffari-Jovin, S.; Santos, K. F.; Hsiao, H.-H.; Will, C. L.; Urlaub, H.; Wahl, M. C. & Luehrmann, R.​ (2012) 
  Genes & Development, 26(21) pp. 2422​-2434​.​ DOI: https://doi.org/10.1101/gad.200949.112 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article
  ​ ​The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes​
  De, I.; Sessonov, S.; Hofele, R. V.; dos Santos, K.; Will, C. L.; Urlaub, H. & Luehrmann, R. et al.​ (2015) 
  Nature Structural & Molecular Biology, 22(2) pp. 138​-144​.​ DOI: https://doi.org/10.1038/nsmb.2951 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​ATP gamma S stalls splicing after B complex formation but prior to spliceosome activation​
  Agafonov, D. E.; van Santen, M.; Kastner, B.; Dube, P.; Will, C. L.; Urlaub, H. & Luehrmann, R.​ (2016) 
  RNA, 22(9) pp. 1329​-1337​.​ DOI: https://doi.org/10.1261/rna.057810.116 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations​
  Cretu, C. ; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De laurentiis, E. I.; Sharma, K. & Will, C. L. et al.​ (2016) 
  Molecular Cell, 64(2) pp. 307​-319​.​ DOI: https://doi.org/10.1016/j.molcel.2016.08.036 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article | 
  ​ ​U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III.​
  Singh, J.; Sikand, K.; Conrad, H.; Will, C. L.; Komar, A. A. & Shukla, G. C.​ (2016) 
  Scientific reports, 6 art. 31393​.​ DOI: https://doi.org/10.1038/srep31393 
  ​Details  DOI  PMID  PMC 

• 2016 | Journal Article | Research Paper | 
  ​ ​A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity​
  Boesler, C.; Rigo, N.; Anokhina, M. M.; Tauchert, M. J. ; Agafonov, D. E.; Kastner, B. & Urlaub, H.  et al.​ (2016) 
  Nature Communications, 7 art. 11997​.​ DOI: https://doi.org/10.1038/ncomms11997 
  ​Details  DOI  PMID  PMC  WoS 

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