Author Wirths, Oliver

• 2007 | Conference Abstract
  ​ ​A beta-induced pathology and neuron loss in the cholinergic system of the APP/PS1ki mouse model of Alzheimer's disease​
  Christensen, D. Z.; Bayer, T. & Wirths, O.​ (2007)
  Biochemical Pharmacology, 74(8) ​Symposium on Nicotinic Acetylcholine Receptors as Therapeutic Targets​, San Diego, CA.
  Oxford​: Pergamon-elsevier Science Ltd.
  ​Details  WoS 

• 2007 | Journal Article
  ​ ​Altered cholesterol metabolism in APP695-transfected neuroblastoma cells​
  Wirths, O.; Thelen, K. M.; Luetjohann, D.; Falkai, P. & Bayer, T. A.​ (2007) 
  Brain Research, 1152 pp. 209​-214​.​ DOI: https://doi.org/10.1016/j.brainres.2007.03.029 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article | 
  ​ ​Effect of copper intake on CSF parameters in patients with mild Alzheimer’s disease: a pilot phase 2 clinical trial​
  Kessler, H.; Pajonk, F.-G.; Bach, D.; Schneider-Axmann, T.; Falkai, P.; Herrmann, W. & Multhaup, G. et al.​ (2008) 
  Journal of Neural Transmission, 115(12) pp. 1651​-1659​.​ DOI: https://doi.org/10.1007/s00702-008-0136-2 
  ​Details  DOI 

• 2008 | Journal Article
  ​ ​Alzheimer's disease Molecular pathology, animal models, and current treatment​
  Bayer, T. A. & Wirths, O.​ (2008) 
  Der Nervenarzt, 79 pp. 117​-125​.​ DOI: https://doi.org/10.1007/s00115-008-2496-0 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Conference Paper
  ​ ​Review on the APP/PS1KI mouse model: intraneuronal A beta accumulation triggers axonopathy, neuron loss and working memory impairment​
  Bayer, T. A. & Wirths, O.​ (2008)
  Genes, Brain and Behavior, 7 pp. 6​-11. ​Annual Meeting of the Genes-Brain-and-Behavior-Society​, Doorwerth, NETHERLANDS.
  Oxford​: Blackwell Publishing. DOI: https://doi.org/10.1111/j.1601-183X.2007.00372.x 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice​
  Cotel, M.-C.; Bayer, T. A. & Wirths, O.​ (2008) 
  Brain Research, 1222 pp. 207​-213​.​ DOI: https://doi.org/10.1016/j.brainres.2008.05.052 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease​
  Wirths, O.; Breyhan, H.; Schaefer, S.; Roth, C. & Bayer, T. A.​ (2008) 
  Neurobiology of Aging, 29(6) pp. 891​-901​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2006.12.004 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Motor impairment in Alzheimer's disease and transgenic Alzheimer's disease mouse models​
  Wirths, O. & Bayer, T. A.​ (2008) 
  Genes, Brain and Behavior, 7 pp. 1​-5​.​ DOI: https://doi.org/10.1111/j.1601-183X.2007.00373.x 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article | 
  ​ ​Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice​
  Christensen, D. Z.; Kraus, S. L.; Flohr, A.; Cotel, M.-C.; Wirths, O. & Bayer, T. A.​ (2008) 
  Acta Neuropathologica, 116(6) pp. 647​-655​.​ DOI: https://doi.org/10.1007/s00401-008-0451-6 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Conference Paper | 
  ​ ​Intraneuronal beta-amyloid is a major risk factor - Novel evidence from the APP/PS1KI mouse model​
  Bayer, T. A.; Breyhan, H.; Duan, K.; Rettig, J. & Wirths, O.​ (2008)
  Neurodegenerative Diseases, 5(3-4) pp. 140​-142. ​8th International Conference on Alzheimers and Parkinsons Diseases​, Salzburg, AUSTRIA.
  Basel​: Karger. DOI: https://doi.org/10.1159/000113684 
  ​Details  DOI  PMID  PMC  WoS 

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