Author Hemmer, Bernhard
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2004 | Conference Abstract
Analysis of the Asp299Gly polymorphism in the Toll-like receptor 4 (TLR-4) gene in patients with multiple sclerosis
Kroner, A.; Rosche, B.; Kolb-Maurer, A.; Kruse, N.; Toyka, K. V.; Hemmer, B. & Rieckmann, P. et al. (2004)
Journal of Neuroimmunology, 154(1-2) 7th International Congress of the International-Society-of-Neuroimmunology, Venice, ITALY.
Amsterdam: Elsevier Science Bv.
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2004 | Review
Advances in understanding and treatment of immune-mediated disorders of the peripheral nervous system
Kieseier, B. C.; Kiefer, R.; Gold, R.; Hemmer, B.; Willison, H. J.& Hartung, H.-P. (2004)
Muscle & Nerve, 30(2) pp. 131-156.
John Wiley & Sons Inc. DOI: https://doi.org/10.1002/mus.20076
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2005 | Conference Abstract
MRI-histopathology correlation in a clonal mouse EAE model
Nessler, S.; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Michaelis, T. & Bruck, W. W. et al. (2005)
Multiple Sclerosis Journal, 11 21st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis/10th Annual Meeting of Rehabilitation in MS, Thessaloniki, GREECE.
London: Hodder Arnold, Hodder Headline Plc.
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2006 | Conference Abstract
MRI correlates of lesion pathology in T-cell clone mediated mouse experimental autoimmune encephalomyelitis
Nessler, S. A.; Boretius, S.; Stadelmann, C. ; Bittner, A.; Merkler, D.; Hartung, H.-P. & Michaelis, T. et al. (2006)
Journal of Neuroimmunology, 178 , Nagoya, JAPAN.
Amsterdam: Elsevier Science Bv.
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2006 | Conference Abstract
Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis
Zhou, D.; Srivastava, R.; Nessler, S.; Grummel, V.; Sommer, N.; Brueck, W. & Hartung, H.-P. et al. (2006)
Journal of Neuroimmunology, 178 , Nagoya, JAPAN.
Amsterdam: Elsevier Science Bv.
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2006 | Journal Article
Suppression of autoimmune encephalomyelitis by a neurokinin-1 receptor antagonist - A putative role for substance P in CNS inflammation
Nessler, S.; Stadelmann, C. ; Bittner, A.; Schlegel, K.; Gronen, F.; Brueck, W. & Hemmer, B. et al. (2006)
Journal of Neuroimmunology, 179(1-2) pp. 1-8. DOI: https://doi.org/10.1016/j.jneuroim.2006.06.026
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2006 | Journal Article
Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis
Zhou, D.; Srivastava, R.; Nessler, S.; Grummel, V.; Sommer, N.; Brueck, W. & Hartung, H.-P. et al. (2006)
Proceedings of the National Academy of Sciences of the United States of America, 103(50) pp. 19057-19062. DOI: https://doi.org/10.1073/pnas.0607242103
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2007 | Journal Article
Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage
Nessler, S. ; Boretius, S. ; Stadelmann, C. ; Bittner, A.; Merkler, D. ; Hartung, H. - P. & Michaelis, T. et al. (2007)
Brain: A Journal of Neurology, 130(8) pp. 2186-2198. DOI: https://doi.org/10.1093/brain/awm105
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2008 | Journal Article
Persistence of Immunopathological and Radiological Traits in Multiple Sclerosis
Koenig, F. B.; Wildemann, B.; Nessler, S.; Zhou, D.; Hemmer, B.; Metz, I. & Hartung, H.-P. et al. (2008)
ARCHIVES OF NEUROLOGY, 65(11) pp. 1527-1532. DOI: https://doi.org/10.1001/archneur.65.11.1527
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2009 | Conference Abstract
Increased axonal damage in p75(NTR)-knockout mice after induction of experimental autoimmune encephalomyelitis by adoptive transfer
Dallenga, T.; Bittner, A.; Jaeger, W.; Vollmar, P.; Oertel, W. H.; Sommer, N. & Moeller, J. C. et al. (2009)
Acta Neuropathologica, 118(3) 54th Annual Meeting of the German-Society-of-Neuropathology-and-Neuroanatomy, Dusseldorf, GERMANY.
New york: Springer.
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2009 | Conference Abstract
Pathogenic anti-aquaporin-4 antibodies are produced by intrathecal clonally-expanded plasma cells in early neuromyelitis optica
Bennett, J. L.; Lam, C. S. P.; Kalluri, S. R.; Saikali, P.; Bautista, K.; Dupree, C. & Glogowska, M. et al. (2009)
MULTIPLE SCLEROSIS, 15(9) 25th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis, Dusseldorf, GERMANY.
London: Sage Publications Ltd.
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2009 | Journal Article | Letter Note |
Free caspase activity in CSF of patients with dementia
Albrecht, P.; Schmitz, M.; Otto, M.; Hemmer, B.; Zerr, I.; Hartung, H.-P. & Methner, A. (2009)
Journal of Neurology, 256(9) pp. 1561-1562. DOI: https://doi.org/10.1007/s00415-009-5145-z
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2009 | Journal Article
Intrathecal Pathogenic Anti-Aquaporin-4 Antibodies in Early Neuromyelitis Optica
Bennett, J. L.; Lam, C.; Kalluri, S. R.; Saikali, P.; Bautista, K.; Dupree, C. & Glogowska, M. et al. (2009)
Annals of Neurology, 66(5) pp. 617-629. DOI: https://doi.org/10.1002/ana.21802
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2010 | Conference Abstract
Molecular small animal imaging in an Experimental Autoimmune Encephalomyelitis (EAE) rat model
Lapa, C.; Buck, D.; Foerschler, A.; Stadelmann, C. ; Wester, H.; Korn, T. & Nessler, S. et al. (2010)
European Journal of Nuclear Medicine and Molecular Imaging, 37 pp. S276-S277. , Vienna, AUSTRIA.
New york: Springer.
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2010 | Journal Article
Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling
Hu, W.; Nessler, S.; Hemmer, B.; Eagar, T. N.; Kane, L. P.; Leliveld, S. R. & Mueller-Schiffmann, A. et al. (2010)
Brain, 133 pp. 375-388. DOI: https://doi.org/10.1093/brain/awp298
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2010 | Journal Article
Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis
Sargsyan, S. A.; Shearer, A. J.; Ritchie, A. M.; Burgoon, M. P.; Anderson, S.; Hemmer, B. & Stadelmann, C. et al. (2010)
Neurology, 74(14) pp. 1127-1135. DOI: https://doi.org/10.1212/WNL.0b013e3181d865a1
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2010 | Journal Article |
Serum antibodies to conformational and linear epitopes of myelin oligodendrocyte glycoprotein are not elevated in the preclinical phase of multiple sclerosis
Chan, A.; Decard, B. F.; Franke, C.; Grummel, V.; Zhou, D.; Schottstedt, V. & Toyka, K. V. et al. (2010)
MULTIPLE SCLEROSIS, 16(10) pp. 1189-1192. DOI: https://doi.org/10.1177/1352458510376406
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2011 | Conference Abstract
Clinicopathological features of a fulminant case of acute disseminated encephalomyelitis
Schirmer, L.; Seifert, C. L.; Pfeifenbring, S.; Wunderlich, S.; Stadelmann, C. & Hemmer, B. (2011)
Journal of Neurology, 258 , Lisbon, PORTUGAL.
Heidelberg: Springer.
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2011 | Journal Article | Letter Note
No Association Between Genetic Polymorphism at Codon 129 of the Prion Protein Gene and Primary Progressive Multiple Sclerosis
Stueve, O.; Wang, J.; Chan, A.; Hemmer, B.; Cepok, S.; Nessler, S. & Zipp, F. et al. (2011)
ARCHIVES OF NEUROLOGY, 68(2) pp. 264-265. DOI: https://doi.org/10.1001/archneurol.2010.354
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2012 | Journal Article |
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
Jarius, S.; Ruprecht, K.; Wildemann, B.; Kuempfel, T.; Ringelstein, M.; Geis, C. & Kleiter, I. et al. (2012)
Journal of Neuroinflammation, 9 art. 14. DOI: https://doi.org/10.1186/1742-2094-9-14
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2012 | Journal Article | Letter Note
Clinicopathological considerations in acute disseminated encephalomyelitis (ADEM): a fulminant case with favorable outcome
Schirmer, L.; Seifert, C. L.; Pfeifenbring, S.; Wunderlich, S.; Stadelmann, C. & Hemmer, B. (2012)
Journal of Neurology, 259(4) pp. 753-755. DOI: https://doi.org/10.1007/s00415-011-6231-6
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2012 | Journal Article |
Favourable response to plasma exchange in tumefactive CNS demyelination with delayed B-cell response
Seifert, C. L.; Wegner, C.; Sprenger, T.; Weber, M. S.; Brueck, W.; Hemmer, B. & Sellner, J. (2012)
Multiple Sclerosis Journal, 18(7) pp. 1045-1049. DOI: https://doi.org/10.1177/1352458511429012
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2012 | Journal Article
F-18-FDG PET Detects Inflammatory Infiltrates in Spinal Cord Experimental Autoimmune Encephalomyelitis Lesions
Buck, D.; Foerschler, A.; Lapa, C.; Schuster, T.; Vollmar, P.; Korn, T. & Nessler, S. et al. (2012)
Journal of Nuclear Medicine, 53(8) pp. 1269-1276. DOI: https://doi.org/10.2967/jnumed.111.102608
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2013 | Conference Abstract
Intrathecal administration of anti-CD20 in treatment of experimental autoimmune encephalomyelitis
Lehmann-Horn, K.; Radelfahr, F.; Hemmer, B. & Weber, M. S. (2013)
Multiple Sclerosis Journal, 19(11) 29th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis / 18th Annual Conference of Rehabilitation in MS, Copenhagen, DENMARK.
London: Sage Publications Ltd.
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2013 | Journal Article |
The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis
Cravens, P. D.; Kieseier, B. C.; Hussain, R. Z.; Herndon, E.; Arellano, B.; Ben, L.-H. & Timmons, B. C. et al. (2013)
Journal of Neuroinflammation, 10 art. 67. DOI: https://doi.org/10.1186/1742-2094-10-67
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2013 | Journal Article
Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity
Hertzenberg, D.; Lehmann-Horn, K.; Kinzel, S.; Husterer, V.; Cravens, P. D.; Kieseier, B. C. & Hemmer, B. et al. (2013)
European Journal of Immunology, 43(8) pp. 2078-2088. DOI: https://doi.org/10.1002/eji.201343338
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2014 | Journal Article
Immune cell subtyping in the cerebrospinal fluid of patients with neurological diseases
Kowarik, M. C.; Grummel, V.; Wemlinger, S.; Buck, D.; Weber, M. S. ; Berthele, A. & Hemmer, B. (2014)
Journal of Neurology, 261(1) pp. 130-143. DOI: https://doi.org/10.1007/s00415-013-7145-2
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2014 | Journal Article |
Intrathecal anti-CD20 efficiently depletes meningeal B cells in CNS autoimmunity
Lehmann-Horn, K.; Kinzel, S.; Feldmann, L.; Radelfahr, F.; Hemmer, B.; Traffehn, S. & Bernard, C. C. A. et al. (2014)
Annals of Clinical and Translational Neurology, 1(7) pp. 490-496. DOI: https://doi.org/10.1002/acn3.71
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2015 | Journal Article
The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model
Geis, C.; Ritter, C.; Ruschil, C.; Weishaupt, A.; Gruenewald, B.; Stoll, G. & Holmoy, T. et al. (2015)
Experimental Neurology, 265 pp. 8-21. DOI: https://doi.org/10.1016/j.expneurol.2014.12.015
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2015 | Journal Article
Current aspects of therapy conversion for multiple sclerosis
Kolber, P.; Luessi, F.; Meuth, S. G.; Klotz, L.; Korn, T.; Trebst, C. & Tackenberg, B. et al. (2015)
Der Nervenarzt, 86(10) pp. 1236-1247. DOI: https://doi.org/10.1007/s00115-015-4368-8
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2015 | Journal Article |
B lymphocytes in neuromyelitis optica.
Bennett, J. L.; O'Connor, K. C.; Bar-Or, A.; Zamvil, S. S.; Hemmer, B.; Tedder, T. F. & von Büdingen, H.-C. et al. (2015)
Neurology® neuroimmunology & neuroinflammation, 2(3) art. e104. DOI: https://doi.org/10.1212/NXI.0000000000000104
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2016 | Journal Article |
In Vivo Imaging Reveals Rapid Astrocyte Depletion and Axon Damage in a Model of Neuromyelitis Optica-Related Pathology
Herwerth, M.; Kalluri, S. R.; Srivastava, R.; Kleele, T.; Kenet, S.; Illes, Z. & Merkler, D. et al. (2016)
Annals of Neurology, 79(5) pp. 794-805. DOI: https://doi.org/10.1002/ana.24630
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2016 | Journal Article
Monitoring of blood parameters under course-modified MS therapy. Substance-specific relevance and current recommendations for action
Klotz, L.; Berthele, A.; Brück, W. ; Chan, A.; Flachenecker, P.; Gold, R. & Haghikia, A. et al. (2016)
Der Nervenarzt, 87(6) pp. 645-659. DOI: https://doi.org/10.1007/s00115-016-0077-1
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2017 | Journal Article
Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response
Stellmann, J.-P.; Krumbholz, M.; Friede, T. ; Gahlen, A.; Borisow, N.; Fischer, K. & Hellwig, K. et al. (2017)
Journal of Neurology, Neurosurgery & Psychiatry, 88(8) pp. 639-647. DOI: https://doi.org/10.1136/jnnp-2017-315603
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2019 | Journal Article |
Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging
Schmidt, P.; Pongratz, V.; Küster, P.; Meier, D.; Wuerfel, J.; Lukas, C. & Bellenberg, B. et al. (2019)
NeuroImage: Clinical, 23 pp. 101849. DOI: https://doi.org/10.1016/j.nicl.2019.101849
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2019 | Journal Article |
Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany
Bittner, S.; Engel, S.; Lange, C.; Weber, M. S. ; Haghikia, A.; Luessi, F. & Korn, T. et al. (2019)
Der Nervenarzt, 90(12) pp. 1245-1253-1253. DOI: https://doi.org/10.1007/s00115-019-0760-0
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2021 | Journal Article
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity
Hiltensperger, M.; Beltrán, E.; Kant, R.; Tyystjärvi, S.; Lepennetier, G.; Domínguez Moreno, H. & Bauer, I. J. et al. (2021)
Nature Immunology, 22(7) pp. 880-892. DOI: https://doi.org/10.1038/s41590-021-00948-8
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2021 | Journal Article
The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis
Cirac, A.; Tsaktanis, T.; Beyer, T.; Linnerbauer, M.; Andlauer, T.; Grummel, V. & Nirschl, L. et al. (2021)
Neurology: Neuroimmunology & Neuroinflammation, 8(5) art. e1043. DOI: https://doi.org/10.1212/NXI.0000000000001043
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2022 | Journal Article | Research Paper |
Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis
Aly, L.; Noll, C.; Wicklein, R.; Wolf, E.; Romahn, E. F.; Wauschkuhn, J. & Hosari, S. et al. (2022)
Neurology: Neuroimmunology & Neuroinflammation, 9(3) art. e1159. DOI: https://doi.org/10.1212/NXI.0000000000001159
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2022 | Journal Article | Research Paper
Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders
Aly, L.; Strauß, E.-M.; Feucht, N.; Weiß, I.; Berthele, A.; Mitsdoerffer, M. & Haass, C. et al. (2022)
Multiple sclerosis, 28(4) pp. 522-531. DOI: https://doi.org/10.1177/13524585211028831
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2022 | Journal Article | Research Paper |
P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica : P2R Inhibitors Prevent Autoantibody Injury
Kalluri, S. R.; Srivastava, R.; Kenet, S.; Tanti, G. K.; Dornmair, K.; Bennett, J. L. & Misgeld, T. et al. (2022)
Neurotherapeutics,. DOI: https://doi.org/10.1007/s13311-022-01269-w
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2023 | Journal Article
Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing-remitting multiple sclerosis
Tsaktanis, T.; Linnerbauer, M.; Lößlein, L.; Farrenkopf, D.; Vandrey, O.; Peter, A. & Cirac, A. et al. (2023)
Brain Communications, 5(4) art. fcad206. DOI: https://doi.org/10.1093/braincomms/fcad206
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2023 | Journal Article |
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination
Kapell, H.; Fazio, L.; Dyckow, J.; Schwarz, S.; Cruz-Herranz, A.; Mayer, C. & Campos, J. et al. (2023)
The Journal of Clinical Investigation, 133(7). DOI: https://doi.org/10.1172/JCI164223
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2023 | Journal Article
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation
Linnerbauer, M.; Beyer, T.; Nirschl, L.; Farrenkopf, D.; Lößlein, L.; Vandrey, O. & Peter, A. et al. (2023)
Nature Communications, 14(1) pp. 5555. DOI: https://doi.org/10.1038/s41467-023-40982-8
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2024 | Journal Article
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy
Ancău, M.; Tanti, G. K.; Butenschoen, V. M.; Gempt, J.; Yakushev, I.; Nekolla, S. & Mühlau, M. et al. (2024)
EBioMedicine, 100 art. 104982. DOI: https://doi.org/10.1016/j.ebiom.2024.104982
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2024 | Journal Article
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
Linnerbauer, M.; Lößlein, L.; Vandrey, O.; Peter, A.; Han, Y.; Tsaktanis, T. & Wogram, E. et al. (2024)
Nature Immunology, 25(3) pp. 432-447. DOI: https://doi.org/10.1038/s41590-024-01756-6
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2024 | Journal Article
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
Afzali, A. M.; Nirschl, L.; Sie, C.; Pfaller, M.; Ulianov, O.; Hassler, T. & Federle, C. et al. (2024)
Nature, 627(8003) pp. 407-415. DOI: https://doi.org/10.1038/s41586-024-07079-8
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