Author Nehlmeier, Inga

1 to 48 of 48 Items
  • 2011 | Journal Article | Research Paper
    ​ ​Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease​
    Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al.​ (2011) 
    Journal of Virology, 85(24) pp. 13363​-13372​.​ DOI: https://doi.org/10.1128/JVI.05300-11 
    ​Details  DOI  PMID  PMC 
  • 2012 | Journal Article
    ​ ​The role of the alternative coreceptor GPR15 in SIV tropism for human cells​
    Kiene, M.; Marzi, A.; Urbanczyk, A.; Bertram, S.; Fisch, T.; Nehlmeier, I. & Gnirß, K. et al.​ (2012) 
    Virology, 433(1) pp. 73​-84​.​ DOI: https://doi.org/10.1016/j.virol.2012.07.012 
    ​Details  DOI 
  • 2012 | Journal Article | 
    ​ ​Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells​
    Winkler, M.; Bertram, S.; Gnirß, K.; Nehlmeier, I.; Gawanbacht, A.; Kirchhoff, F. & Ehrhardt, C. et al.​ (2012) 
    PLoS ONE, 7(8) art. e43337​.​ DOI: https://doi.org/10.1371/journal.pone.0043337 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​DESC1 and MSPL Activate Influenza A Viruses and Emerging Coronaviruses for Host Cell Entry​
    Zmora, P.; Blazejewska, P.; Moldenhauer, A.-S.; Welsch, K.; Nehlmeier, I.; Wu, Q. & Schneider, H. et al.​ (2014) 
    Journal of Virology, 88(20) pp. 12087​-12097​.​ DOI: https://doi.org/10.1128/JVI.01427-14 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase​
    Gnirß, K.; Zmora, P.; Blazejewska, P.; Winkler, M.; Lins, A.; Nehlmeier, I. & Gärtner, S. et al.​ (2015) 
    Journal of Virology, 89(18) pp. 9178​-9188​.​ DOI: https://doi.org/10.1128/JVI.00615-15 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.​
    Karsten, C. B.; Buettner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A. & Sauermann, U. et al.​ (2015) 
    Journal of virology, 89(22) pp. 11727​-11733​.​ DOI: https://doi.org/10.1128/JVI.01358-15 
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  • 2016 | Journal Article
    ​ ​Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions​
    Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang, H.; Wang, W. & Pöhlmann, S. et al.​ (2016) 
    Angewandte Chemie International Edition, 55(15) pp. 4738​-4742​.​ DOI: https://doi.org/10.1002/anie.201600593 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies​
    Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al.​ (2016) 
    Journal of Virology, 90(24) pp. 11075​-11086​.​ DOI: https://doi.org/10.1128/JVI.01563-16 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry​
    Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al.​ (2017) 
    Journal of Virology, 91(9) art. e00177-17​.​ DOI: https://doi.org/10.1128/JVI.00177-17 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins​
    Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S.​ (2017) 
    Journal of Virology, 91(2) art. e01488-16​.​ DOI: https://doi.org/10.1128/JVI.01488-16 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper | 
    ​ ​The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells​
    Brinkmann, C.; Hoffmann, M.; Lübke, A.; Nehlmeier, I.; Krämer-Kühl, A.; Winkler, M.   & Pöhlmann, S. ​ (2017) 
    PLoS One, 12(12) art. e0189073​.​ DOI: https://doi.org/10.1371/journal.pone.0189073 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.​
    Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al.​ (2017) 
    PloS one, 12(6) art. e0179177​.​ DOI: https://doi.org/10.1371/journal.pone.0179177 
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  • 2017 | Journal Article | 
    ​ ​Dissecting Multivalent Lectin–Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots​
    Guo, Y.; Nehlmeier, I.; Poole, E.; Sakonsinsiri, C.; Hondow, N.; Brown, A. & Li, Q. et al.​ (2017) 
    Journal of the American Chemical Society, 139(34) pp. 11833​-11844​.​ DOI: https://doi.org/10.1021/jacs.7b05104 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin​
    Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al.​ (2017) 
    PLOS ONE, 12(5) art. e0176597​.​ DOI: https://doi.org/10.1371/journal.pone.0176597 
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  • 2019 | Journal Article
    ​ ​Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis​
    Lambertz, R. L. O.; Gerhauser, I.; Nehlmeier, I.; Leist, S. R.; Kollmus, H.; Pöhlmann, S.   & Schughart, K.​ (2019) 
    Journal of General Virology, 100(7) pp. 1073​-1078​.​ DOI: https://doi.org/10.1099/jgv.0.001274 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways​
    Laporte, M.; Stevaert, A.; Raeymaekers, V.; Boogaerts, T.; Nehlmeier, I.; Chiu, W. & Benkheil, M. et al.​ (2019) 
    Journal of Virology, 94(1).​ DOI: https://doi.org/10.1128/JVI.01430-19 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells​
    Hoffmann, M.; Nehlmeier, I.; Brinkmann, C.; Krähling, V.; Behner, L.; Moldenhauer, A.-S. & Krüger, N. et al.​ (2019) 
    Journal of Virology, 93(3).​ DOI: https://doi.org/10.1128/JVI.01821-18 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins​
    Plegge, T.; Spiegel, M.; Krüger, N.; Nehlmeier, I.; Winkler, M.; González Hernández, M. & Pöhlmann, S.​ (2019) 
    PLOS ONE, 14(4) art. e0214968​.​ DOI: https://doi.org/10.1371/journal.pone.0214968 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article | 
    ​ ​Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques​
    Winkler, M. ; Gärtner, S.; Markus, L.; Hoffmann, M.; Nehlmeier, I.; Krawczak, M.   & Sauermann, U. et al.​ (2019) 
    PLoS One, 14(11) art. e0224082​.​ DOI: https://doi.org/10.1371/journal.pone.0224082 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin–Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly​
    Budhadev, D.; Poole, E.; Nehlmeier, I.; Liu, Y.; Hooper, J.; Kalverda, E. & Akshath, U. S. et al.​ (2020) 
    Journal of the American Chemical Society, 142(42) pp. 18022​-18034​.​ DOI: https://doi.org/10.1021/jacs.0c06793 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice​
    Lambertz, R. L. O.; Gerhauser, I.; Nehlmeier, I.; Gärtner, S.; Winkler, M. ; Leist, S. R. & Kollmus, H. et al.​ (2020) 
    Virology Journal, 17(1).​ DOI: https://doi.org/10.1186/s12985-020-01323-z 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination​
    Hoffmann, M.; Hofmann-Winkler, H.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Arora, P. et al.​ (2021) 
    Cell Reports, 36(3) art. S2211124721008287​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109415 
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  • 2021 | Journal Article
    ​ ​SARS-CoV-2 delta variant neutralisation after heterologous ChAdOx1-S/BNT162b2 vaccination​
    Behrens, G. M.; Cossmann, A.; Stankov, M. V; Nehlmeier, I.; Kempf, A.; Hoffmann, M. & Pöhlmann, S.​ (2021) 
    The Lancet, 398(10305) pp. 1041​-1042​.​ DOI: https://doi.org/10.1016/S0140-6736(21)01891-2 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination​
    Arora, P.; Sidarovich, A.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Moldenhauer, A.-S. et al.​ (2021) 
    Cell Reports, 37(2) art. S2211124721012894​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109825 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Sidarovich, A.; Winkler, M. S. & Schulz, S. et al.​ (2021) 
    Cellular & Molecular Immunology, 18(11) pp. 2557​-2559​.​ DOI: https://doi.org/10.1038/s41423-021-00772-y 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency​
    Arora, P.; Rocha, C.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S. & Lier, M. et al.​ (2021) 
    Cellular & Molecular Immunology, 18(12) pp. 2673​-2675​.​ DOI: https://doi.org/10.1038/s41423-021-00779-5 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy​
    Hoffmann, M.; Sidarovich, A.; Arora, P.; Krüger, N.; Nehlmeier, I.; Kempf, A. & Graichen, L. et al.​ (2022) 
    mBio,.​ DOI: https://doi.org/10.1128/mbio.00364-22 
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  • 2022 | Journal Article
    ​ ​SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S.; Lier, M. & Schulz, S. et al.​ (2022) 
    Cell Reports, art. S2211124722005186​.​ DOI: https://doi.org/10.1016/j.celrep.2022.110754 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Augmented neutralisation resistance of emerging omicron subvariants BA.2.12.1, BA.4, and BA.5​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Cossmann, A.; Stankov, M. V & Jäck, H.-M. et al.​ (2022) 
    The Lancet Infectious Diseases, 22(8) pp. 1117​-1118​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00422-4 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Omicron sublineage BQ.1.1 resistance to monoclonal antibodies​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Jäck, H.-M.; Pöhlmann, S. & Hoffmann, M.​ (2022) 
    The Lancet Infectious Diseases,.​ DOI: https://doi.org/10.1016/S1473-3099(22)00733-2 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic​
    Hoffmann, M.; Krüger, N.; Schulz, S.; Cossmann, A.; Rocha, C.; Kempf, A. & Nehlmeier, I. et al.​ (2022) 
    Cell, 185(3) pp. 447​-456.e11​.​ DOI: https://doi.org/10.1016/j.cell.2021.12.032 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Lung cell entry, cell–cell fusion capacity, and neutralisation sensitivity of omicron sublineage BA.2.75​
    Arora, P.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Schulz, S. R; Dopfer-Jablonka, A. & Baier, E. et al.​ (2022) 
    The Lancet Infectious Diseases,.​ DOI: https://doi.org/10.1016/S1473-3099(22)00591-6 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S.; Lier, M. & Schulz, S. et al.​ (2022) 
    Cellular & Molecular Immunology,.​ DOI: https://doi.org/10.1038/s41423-021-00811-8 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2​
    Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Schulz, S.; Cossmann, A. & Dopfer-Jablonka, A. et al.​ (2022) 
    Cellular & Molecular Immunology,.​ DOI: https://doi.org/10.1038/s41423-022-00870-5 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Native and activated antithrombin inhibits TMPRSS2 activity and SARS‐CoV‐2 infection​
    Wettstein, L.; Immenschuh, P.; Weil, T.; Conzelmann, C.; Almeida‐Hernández, Y.; Hoffmann, M. & Kempf, A. et al.​ (2022) 
    Journal of Medical Virology, art. jmv.28124​.​ DOI: https://doi.org/10.1002/jmv.28124 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​The effect of cilgavimab and neutralisation by vaccine-induced antibodies in emerging SARS-CoV-2 BA.4 and BA.5 sublineages​
    Arora, P.; Zhang, L.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Dopfer-Jablonka, A. & Schulz, S. R et al.​ (2022) 
    The Lancet Infectious Diseases, 22(12) pp. 1665​-1666​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00693-4 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1​
    Sidarovich, A.; Krüger, N.; Rocha, C.; Graichen, L.; Kempf, A.; Nehlmeier, I. & Lier, M. et al.​ (2022) 
    Viruses, 14(11) art. 2475​.​ DOI: https://doi.org/10.3390/v14112475 
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  • 2022 | Journal Article | 
    ​ ​The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant​
    Arora, P.; Zhang, L.; Rocha, C.; Graichen, L.; Nehlmeier, I.; Kempf, A. & Cossmann, A. et al.​ (2022) 
    International Journal of Molecular Sciences, 23(22) pp. 14057​.​ DOI: https://doi.org/10.3390/ijms232214057 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein​
    Budhadev, D.; Hooper, J.; Rocha, C.; Nehlmeier, I.; Kempf, A. M.; Hoffmann, M. & Krüger, N. et al.​ (2023) 
    JACS Au, 3(6) pp. 1755​-1766​.​ DOI: https://doi.org/10.1021/jacsau.3c00163 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation​
    Hoffmann, M.; Behrens, G. M N; Arora, P.; Kempf, A.; Nehlmeier, I.; Cossmann, A. & Manthey, L. et al.​ (2023) 
    The Lancet Infectious Diseases, 23(1) pp. 25​-28​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00792-7 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Omicron subvariant BA.5 efficiently infects lung cells​
    Hoffmann, M.; Wong, L. Wong, Lok-Yin Roy; Arora, P.; Zhang, L.; Rocha, C.; Odle, A. & Nehlmeier, I. et al.​ (2023) 
    Nature Communications, 14(1).​ DOI: https://doi.org/10.1038/s41467-023-39147-4 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Neutralisation sensitivity of SARS-CoV-2 lineages EG.5.1 and XBB.2.3​
    Zhang, L.; Kempf, A.; Nehlmeier, I.; Cossmann, A.; Dopfer-Jablonka, A.; Stankov, M. V & Schulz, S. R et al.​ (2023) 
    The Lancet Infectious Diseases, 23(10) pp. e391​-e392​.​ DOI: https://doi.org/10.1016/S1473-3099(23)00547-9 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection​
    Metzdorf, K.; Jacobsen, H.; Greweling-Pils, M. C.; Hoffmann, M.; Lüddecke, T.; Miller, F. & Melcher, L. et al.​ (2023) 
    Viruses, 15(2).​ DOI: https://doi.org/10.3390/v15020271 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5​
    Hoffmann, M.; Arora, P.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Schulz, S. R. & Morillas Ramos, G. et al.​ (2023) 
    Cellular & Molecular Immunology, 20(4) pp. 419​-422​.​ DOI: https://doi.org/10.1038/s41423-023-00988-0 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article | 
    ​ ​Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage​
    Nehlmeier, I.; Kempf, A.; Arora, P.; Cossmann, A.; Dopfer-Jablonka, A.; Stankov, M. V. & Schulz, S. R. et al.​ (2023) 
    Cellular & Molecular Immunology, pp. 1​-3​.​ DOI: https://doi.org/10.1038/s41423-023-01030-z 
    ​Details  DOI  PMID  PMC 
  • 2024 | Journal Article
    ​ ​Immune responses following BNT162b2 XBB.1.5 vaccination in patients on haemodialysis in Germany​
    Cossmann, A.; Hoffmann, M.; Stankov, M. V; Lürken, K.; Morillas Ramos, G.; Kempf, A. & Nehlmeier, I. et al.​ (2024) 
    The Lancet Infectious Diseases,.​ DOI: https://doi.org/10.1016/S1473-3099(23)00783-1 
    ​Details  DOI 
  • 2024 | Journal Article
    ​ ​SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency​
    Zhang, L.; Kempf, A.; Nehlmeier, I.; Cossmann, A.; Richter, A.; Bdeir, N. & Graichen, L. et al.​ (2024) 
    Cell, 187(3) pp. 596​-608.e17​.​ DOI: https://doi.org/10.1016/j.cell.2023.12.025 
    ​Details  DOI 
  • 2024 | Journal Article
    ​ ​Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y​
    Oliveira, B. R.; Nehlmeier, I.; Kempf, A. M.; Venugopalan, V.; Rehders, M.; Ceniza, M. E. & Cavalcanti, P. A. T. et al.​ (2024) 
    Biochimie,.​ DOI: https://doi.org/10.1016/j.biochi.2024.02.006 
    ​Details  DOI 

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