Author Pöhlmann, Stefan

• 1999 | Journal Article
  ​ ​Co‐receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo​
  Pöhlmann, S.; Stolte, N.; Münch, J.; Ten Haaft, P.; Heeney, J.; Stahl‐Hennig, C. & Kirchhoff, F.​ (1999) 
  The Journal of Infectious Diseases, 180(5) pp. 1494​-1502​.​ DOI: https://doi.org/10.1086/315097 
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• 2007 | Journal Article
  ​ ​A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo​
  Pöhlmann, S.; Münch, J.; Aziz, S.; Reeves, J. D.; Otto, C.; Leslie, G. J. & Hofmann, H. et al.​ (2007) 
  Virology, 360(2) pp. 275​-285​.​ DOI: https://doi.org/10.1016/j.virol.2006.10.020 
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• 2011 | Journal Article
  ​ ​Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells​
  Kühl, A.; Hoffmann, M.; Müller, M. A.; Munster, V. J.; Gnirß, K.; Kiene, M. & Tsegaye, T. S. et al.​ (2011) 
  The Journal of Infectious Diseases, 204(suppl_3) pp. S840​-S849​.​ DOI: https://doi.org/10.1093/infdis/jir306 
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• 2011 | Journal Article
  ​ ​The Ebola Virus Glycoprotein and HIV-1 Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin​
  Kühl, A.; Banning, C.; Marzi, A.; Votteler, J.; Steffen, I.; Bertram, S. & Glowacka, I. et al.​ (2011) 
  The Journal of Infectious Diseases, 204(Suppl. 3) pp. S850​-S860​.​ DOI: https://doi.org/10.1093/infdis/jir378 
  ​Details  DOI 

• 2011 | Journal Article
  ​ ​Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response​
  Glowacka, I.; Bertram, S.; Müller, M. A.; Allen, P.; Soilleux, E.; Pfefferle, S. & Steffen, I. et al.​ (2011) 
  Journal of Virology, 85(9) pp. 4122​-4134​.​ DOI: https://doi.org/10.1128/JVI.02232-10 
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• 2011 | Journal Article
  ​ ​Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion​
  Simmons, G.; Bertram, S.; Glowacka, I.; Steffen, I.; Chaipan, C.; Agudelo, J. & Lu, K. et al.​ (2011) 
  Virology, 413(2) pp. 265​-274​.​ DOI: https://doi.org/10.1016/j.virol.2011.02.020 
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• 2011 | Journal Article
  ​ ​DC-SIGN: Access Portal for Sweet Viral Killers​
  Hofmann, H. & Pöhlmann, S.​ (2011) 
  Cell Host & Microbe, 10(1) pp. 5​-7​.​ DOI: https://doi.org/10.1016/j.chom.2011.07.003 
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• 2011 | Journal Article | Research Paper
  ​ ​Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease​
  Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al.​ (2011) 
  Journal of Virology, 85(24) pp. 13363​-13372​.​ DOI: https://doi.org/10.1128/JVI.05300-11 
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• 2012 | Journal Article
  ​ ​Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression​
  Gnirß, K.; Kühl, A.; Karsten, C.; Glowacka, I.; Bertram, S.; Kaup, F. & Hofmann, H. et al.​ (2012) 
  Virology, 424(1) pp. 3​-10​.​ DOI: https://doi.org/10.1016/j.virol.2011.11.031 
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• 2012 | Journal Article | 
  ​ ​Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts​
  Bertram, S.; Heurich, A.; Lavender, H.; Gierer, S.; Danisch, S.; Perin, P. & Lucas, J. M. et al.​ (2012) 
  PLoS ONE, 7(4) art. e35876​.​ DOI: https://doi.org/10.1371/journal.pone.0035876 
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• 2012 | Journal Article | 
  ​ ​Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells​
  Winkler, M.; Bertram, S.; Gnirß, K.; Nehlmeier, I.; Gawanbacht, A.; Kirchhoff, F. & Ehrhardt, C. et al.​ (2012) 
  PLoS ONE, 7(8) art. e43337​.​ DOI: https://doi.org/10.1371/journal.pone.0043337 
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• 2012 | Journal Article | 
  ​ ​Host Cell Factors in Filovirus Entry: Novel Players, New Insights​
  Hofmann-Winkler, H.; Kaup, F. & Pöhlmann, S.​ (2012) 
  Viruses, 4(12) pp. 3336​-3362​.​ DOI: https://doi.org/10.3390/v4123336 
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• 2013 | Journal Article
  ​ ​Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN as a Receptor for pH-Dependent Entry into Human and Animal Cell Lines​
  Hofmann, H.; Li, X.; Zhang, X.; Liu, W.; Kühl, A.; Kaup, F. & Soldan, S. S. et al.​ (2013) 
  Journal of Virology, 87(8) pp. 4384​-4394​.​ DOI: https://doi.org/10.1128/JVI.02628-12 
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• 2013 | Journal Article
  ​ ​Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia​
  Gierer, S.; Hofmann-Winkler, H.; Albuali, W. H.; Bertram, S.; Al-Rubaish, A. M.; Yousef, A. A. & Al-Nafaie, A. N. et al.​ (2013) 
  Emerging Infectious Diseases, 19(12) pp. 2034​-2036​.​ DOI: https://doi.org/10.3201/eid1912.130701 
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• 2013 | Journal Article
  ​ ​Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research​
  Simmons, G.; Zmora, P.; Gierer, S.; Heurich, A. & Pöhlmann, S.​ (2013) 
  Antiviral Research, 100(3) pp. 605​-614​.​ DOI: https://doi.org/10.1016/j.antiviral.2013.09.028 
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• 2013 | Journal Article
  ​ ​The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies​
  Gierer, S.; Bertram, S.; Kaup, F.; Wrensch, F.; Heurich, A.; Krämer-Kühl, A. & Welsch, K. et al.​ (2013) 
  Journal of Virology, 87(10) pp. 5502​-5511​.​ DOI: https://doi.org/10.1128/JVI.00128-13 
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• 2013 | Journal Article
  ​ ​TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium​
  Bertram, S.; Dijkman, R.; Habjan, M.; Heurich, A.; Gierer, S.; Glowacka, I. & Welsch, K. et al.​ (2013) 
  Journal of Virology, 87(11) pp. 6150​-6160​.​ DOI: https://doi.org/10.1128/JVI.03372-12 
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• 2013 | Journal Article | 
  ​ ​Platelet activation suppresses HIV-1 infection of T cells​
  Solomon Tsegaye, T.; Gnirß, K.; Rahe-Meyer, N.; Kiene, M.; Krämer-Kühl, A.; Behrens, G. & Münch, J. et al.​ (2013) 
  Retrovirology, 10(1) art. 48​.​ DOI: https://doi.org/10.1186/1742-4690-10-48 
  ​Details  DOI 

• 2013 | Book Chapter
  ​ ​Cellular entry of retroviruses​
  Lindemann, D.; Steffen, I.& Pöhlmann, S.​ (2013)
  In:​Pöhlmann, Stefan; Simmons, Graham​ (Eds.), Viral Entry into Host Cells pp. 128​-149. ​New York: ​Springer. DOI: https://doi.org/10.1007/978-1-4614-7651-1_7 
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• 2014 | Journal Article
  ​ ​The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry​
  Gehring, G.; Rohrmann, K.; Atenchong, N.; Mittler, E.; Becker, S.; Dahlmann, F. & Pöhlmann, S. et al.​ (2014) 
  Journal of Antimicrobial Chemotherapy, 69(8) pp. 2123​-2131​.​ DOI: https://doi.org/10.1093/jac/dku091 
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• 2014 | Journal Article
  ​ ​Bitter-sweet symphony: glycan–lectin interactions in virus biology​
  Van Breedam, W.; Pöhlmann, S.; Favoreel, H. W.; de Groot, R. J. & Nauwynck, H. J.​ (2014) 
  FEMS Microbiology Reviews, 38(4) pp. 598​-632​.​ DOI: https://doi.org/10.1111/1574-6976.12052 
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• 2014 | Journal Article
  ​ ​DESC1 and MSPL Activate Influenza A Viruses and Emerging Coronaviruses for Host Cell Entry​
  Zmora, P.; Blazejewska, P.; Moldenhauer, A.-S.; Welsch, K.; Nehlmeier, I.; Wu, Q. & Schneider, H. et al.​ (2014) 
  Journal of Virology, 88(20) pp. 12087​-12097​.​ DOI: https://doi.org/10.1128/JVI.01427-14 
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• 2014 | Journal Article | 
  ​ ​IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms​
  Wrensch, F.; Winkler, M. & Pöhlmann, S.​ (2014) 
  Viruses, 6(9) pp. 3683​-3698​.​ DOI: https://doi.org/10.3390/v6093683 
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• 2014 | Journal Article | 
  ​ ​Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism​
  Gnirß, K.; Fiedler, M.; Krämer-Kühl, A.; Bolduan, S.; Mittler, E.; Becker, S. & Schindler, M. et al.​ (2014) 
  Viruses, 6(4) pp. 1654​-1671​.​ DOI: https://doi.org/10.3390/v6041654 
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• 2014 | Journal Article | 
  ​ ​Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4+ T Cells​
  Kiene, M.; Rethi, B.; Jansson, M.; Dillon, S.; Lee, E.; Lantto, R. & Wilson, C. et al.​ (2014) 
  PLoS ONE, 9(2) art. e88195​.​ DOI: https://doi.org/10.1371/journal.pone.0088195 
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• 2014 | Journal Article | Research Paper
  ​ ​TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein​
  Heurich, A.; Hofmann-Winkler, H.; Gierer, S.; Liepold, T.; Jahn, O.   & Pöhlmann, S.​ (2014) 
  Journal of Virology, 88(2) pp. 1293​-1307​.​ DOI: https://doi.org/10.1128/JVI.02202-13 
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• 2015 | Journal Article
  ​ ​Interferon-Induced Transmembrane Protein–Mediated Inhibition of Host Cell Entry of Ebolaviruses​
  Wrensch, F.; Karsten, C. B.; Gnirß, K.; Hoffmann, M.; Lu, K.; Takada, A. & Winkler, M. et al.​ (2015) 
  Journal of Infectious Diseases, 212(suppl 2) pp. S210​-S218​.​ DOI: https://doi.org/10.1093/infdis/jiv255 
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• 2015 | Journal Article
  ​ ​Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976​
  Hofmann-Winkler, H.; Gnirß, K.; Wrensch, F. & Pöhlmann, S.​ (2015) 
  Journal of Infectious Diseases, 212(Suppl. 2) pp. S172​-S180​.​ DOI: https://doi.org/10.1093/infdis/jiv101 
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• 2015 | Journal Article
  ​ ​Protease inhibitors targeting coronavirus and filovirus entry​
  Zhou, Y.; Vedantham, P.; Lu, K.; Agudelo, J.; Carrion, R.; Nunneley, J. W. & Barnard, D. et al.​ (2015) 
  Antiviral Research, 116 pp. 76​-84​.​ DOI: https://doi.org/10.1016/j.antiviral.2015.01.011 
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• 2015 | Journal Article | 
  ​ ​TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.​
  Zmora, P.; Moldenhauer, A.-S.; Hofmann-Winkler, H. & Pöhlmann, S.​ (2015) 
  PloS one, 10(9) art. e0138380​.​ DOI: https://doi.org/10.1371/journal.pone.0138380 
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• 2015 | Journal Article | 
  ​ ​Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.​
  Karsten, C. B.; Buettner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A. & Sauermann, U. et al.​ (2015) 
  Journal of virology, 89(22) pp. 11727​-11733​.​ DOI: https://doi.org/10.1128/JVI.01358-15 
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• 2016 | Journal Article
  ​ ​Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions​
  Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang, H.; Wang, W. & Pöhlmann, S. et al.​ (2016) 
  Angewandte Chemie International Edition, 55(15) pp. 4738​-4742​.​ DOI: https://doi.org/10.1002/anie.201600593 
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• 2016 | Journal Article
  ​ ​The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases​
  Kühn, N.; Bergmann, S.; Kösterke, N.; Lambertz, R. L. O.; Keppner, A.; van den Brand, J. M. A. & Pöhlmann, S. et al.​ (2016) 
  Journal of Virology, 90(9) pp. 4298​-4307​.​ DOI: https://doi.org/10.1128/JVI.02693-15 
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• 2016 | Journal Article
  ​ ​The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies​
  Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al.​ (2016) 
  Journal of Virology, 90(24) pp. 11075​-11086​.​ DOI: https://doi.org/10.1128/JVI.01563-16 
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• 2016 | Journal Article | 
  ​ ​The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release.​
  Spiegel, M.; Plegge, T. & Pöhlmann, S.​ (2016) 
  Viruses, 8(7).​ DOI: https://doi.org/10.3390/v8070202 
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• 2016 | Journal Article | 
  ​ ​The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.​
  Hoffmann, M.; González Hernández, M.; Berger, E.; Marzi, A. & Pöhlmann, S.​ (2016) 
  PloS one, 11(2) art. e0149651​.​ DOI: https://doi.org/10.1371/journal.pone.0149651 
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• 2016 | Journal Article | 
  ​ ​The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.​
  Hoffmann, M.; Krüger, N.; Zmora, P.; Wrensch, F.; Herrler, G. & Pöhlmann, S.​ (2016) 
  PloS one, 11(3) art. e0152134​.​ DOI: https://doi.org/10.1371/journal.pone.0152134 
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• 2016 | Journal Article | 
  ​ ​Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide​
  Plegge, T.; Hofmann-Winkler, H.; Spiegel, M. & Pöhlmann, S.​ (2016) 
  PLOS ONE, 11(11) art. e0166013​.​ DOI: https://doi.org/10.1371/journal.pone.0166013 
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• 2017 | Journal Article
  ​ ​A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry​
  Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al.​ (2017) 
  Journal of Virology, 91(9) art. e00177-17​.​ DOI: https://doi.org/10.1128/JVI.00177-17 
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• 2017 | Journal Article
  ​ ​Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset​
  Pöhlmann, S.; Suntz, M.; Akimkin, V.; Bleyer, M. & Kaul, A.​ (2017) 
  Journal of Medical Primatology, 46(5) pp. 256​-259​.​ DOI: https://doi.org/10.1111/jmp.12269 
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• 2017 | Journal Article
  ​ ​pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs​
  Gerlach, T.; Hensen, L.; Matrosovich, T.; Bergmann, J.; Winkler, M.; Peteranderl, C. & Klenk, H.-D. et al.​ (2017) 
  Journal of Virology, 91(11) art. e00246-17​.​ DOI: https://doi.org/10.1128/JVI.00246-17 
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• 2017 | Journal Article
  ​ ​Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins​
  Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S.​ (2017) 
  Journal of Virology, 91(2) art. e01488-16​.​ DOI: https://doi.org/10.1128/JVI.01488-16 
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• 2017 | Journal Article | 
  ​ ​Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.​
  Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al.​ (2017) 
  PloS one, 12(6) art. e0179177​.​ DOI: https://doi.org/10.1371/journal.pone.0179177 
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• 2017 | Journal Article | 
  ​ ​Dissecting Multivalent Lectin–Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots​
  Guo, Y.; Nehlmeier, I.; Poole, E.; Sakonsinsiri, C.; Hondow, N.; Brown, A. & Li, Q. et al.​ (2017) 
  Journal of the American Chemical Society, 139(34) pp. 11833​-11844​.​ DOI: https://doi.org/10.1021/jacs.7b05104 
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• 2017 | Journal Article | 
  ​ ​Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin​
  Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al.​ (2017) 
  PLOS ONE, 12(5) art. e0176597​.​ DOI: https://doi.org/10.1371/journal.pone.0176597 
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• 2017 | Journal Article | 
  ​ ​Rhesus macaque IFITM3 gene polymorphisms and SIV infection​
  Winkler, M.; Gärtner, S.; Wrensch, F.; Krawczak, M.; Sauermann, U. & Pöhlmann, S.​ (2017) 
  PLOS ONE, 12(3) art. e0172847​.​ DOI: https://doi.org/10.1371/journal.pone.0172847 
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• 2018 | Journal Article
  ​ ​A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism​
  González-Hernández, M.; Hoffmann, M.; Brinkmann, C.; Nehls, J.; Winkler, M.; Schindler, M. & Pöhlmann, S.​ (2018) 
  Journal of Virology, 92(13) art. e00403-18​.​ DOI: https://doi.org/10.1128/JVI.00403-18 
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• 2018 | Journal Article
  ​ ​Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2​
  Hoffmann, M. & Pöhlmann, S.​ (2018) 
  Cell Host & Microbe, 23(6) pp. 697​-699​.​ DOI: https://doi.org/10.1016/j.chom.2018.05.019 
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• 2019 | Journal Article
  ​ ​Seroprevalence of viral infections in captive rhesus and cynomolgus macaques​
  Kaul, A.; Schönmann, U. & Pöhlmann, S.​ (2019) 
  Primate Biology, 6(1) pp. 1​-6​.​ DOI: https://doi.org/10.5194/pb-6-1-2019 
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• 2019 | Journal Article | 
  ​ ​Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins​
  Braun, E.; Hotter, D.; Koepke, L.; Zech, F.; Groß, R.; Sparrer, K. M. & Müller, J. A. et al.​ (2019) 
  Cell Reports, 27(7) art. 2104.e10​.​ DOI: https://doi.org/10.1016/j.celrep.2019.04.063 
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• 2019 | Journal Article | 
  ​ ​Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins​
  Plegge, T.; Spiegel, M.; Krüger, N.; Nehlmeier, I.; Winkler, M.; González Hernández, M. & Pöhlmann, S.​ (2019) 
  PLOS ONE, 14(4) art. e0214968​.​ DOI: https://doi.org/10.1371/journal.pone.0214968 
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• 2019 | Journal Article | 
  ​ ​A system for production of defective interfering particles in the absence of infectious influenza A virus​
  Bdeir, N.; Arora, P.; Gärtner, S.; Hoffmann, M.; Reichl, U.; Pöhlmann, S. & Winkler, M.​ (2019) 
  PlOS ONE, 14(3) art. e0212757​.​ DOI: https://doi.org/10.1371/journal.pone.0212757 
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• 2020 | Journal Article | 
  ​ ​Camostat Mesylate May Reduce Severity of Coronavirus Disease 2019 Sepsis: A First Observation​
  Hofmann-Winkler, H.; Moerer, O.; Alt-Epping, S.; Bräuer, A.; Büttner, B.; Müller, M. & Fricke, T. et al.​ (2020) 
  Critical Care Explorations, 2(11) art. e0284​.​ DOI: https://doi.org/10.1097/CCE.0000000000000284 
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• 2021 | Journal Article
  ​ ​SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination​
  Hoffmann, M.; Hofmann-Winkler, H.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Arora, P. et al.​ (2021) 
  Cell Reports, 36(3) art. S2211124721008287​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109415 
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• 2021 | Journal Article
  ​ ​SARS-CoV-2 delta variant neutralisation after heterologous ChAdOx1-S/BNT162b2 vaccination​
  Behrens, G. M.; Cossmann, A.; Stankov, M. V; Nehlmeier, I.; Kempf, A.; Hoffmann, M. & Pöhlmann, S.​ (2021) 
  The Lancet, 398(10305) pp. 1041​-1042​.​ DOI: https://doi.org/10.1016/S0140-6736(21)01891-2 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization​
  Hoffmann, M.; Zhang, L.; Krüger, N.; Graichen, L.; Kleine-Weber, H.; Hofmann-Winkler, H. & Kempf, A. et al.​ (2021) 
  Cell Reports, 35(3) pp. 109017​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109017 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies​
  Hoffmann, M.; Arora, P.; Groß, R.; Seidel, A.; Hörnich, B. F.; Hahn, A. S. & Krüger, N. et al.​ (2021) 
  Cell, 184(9) pp. 2384​-2393.e12​.​ DOI: https://doi.org/10.1016/j.cell.2021.03.036 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection​
  Imre, G.; Krähling, V.; Eichler, M.; Trautmann, S.; Ferreirós, N.; Aman, M. J. & Kashanchi, F. et al.​ (2021) 
  iScience, 24(4) pp. 102266​.​ DOI: https://doi.org/10.1016/j.isci.2021.102266 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity​
  Hoffmann, M.; Hofmann-Winkler, H.; Smith, J. C.; Krüger, N.; Arora, P.; Sørensen, L. K. & Søgaard, O. S. et al.​ (2021) 
  EBioMedicine, 65 art. 103255​.​ DOI: https://doi.org/10.1016/j.ebiom.2021.103255 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection​
  Krüger, N.; Rocha, C.; Runft, S.; Krüger, J.; Färber, I.; Armando, F. & Leitzen, E. et al.​ (2021) 
  International Journal of Molecular Sciences, 22(19) pp. 10636​.​ DOI: https://doi.org/10.3390/ijms221910636 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1​
  Hoffmann, M. & Pöhlmann, S.​ (2021) 
  Cell Research, 32(1) pp. 1​-2​.​ DOI: https://doi.org/10.1038/s41422-021-00603-9 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles​
  Hein, M. D.; Arora, P.; Marichal-Gallardo, P.; Winkler, M.; Genzel, Y.; Pöhlmann, S. & Schughart, K. et al.​ (2021) 
  BMC Biology, 19(1) art. 91​.​ DOI: https://doi.org/10.1186/s12915-021-01020-5 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activity​
  Bdeir, N.; Arora, P.; Gärtner, S.; Pöhlmann, S. & Winkler, M.​ (2021) 
  Scientific Reports, 11(1) art. 20477​.​ DOI: https://doi.org/10.1038/s41598-021-99691-1 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Activation of Sphingomyelinase-Ceramide-Pathway in COVID-19 Purposes Its Inhibition for Therapeutic Strategies​
  Abusukhun, M.; Winkler, M. S.; Pöhlmann, S.; Moerer, O.; Meissner, K.; Tampe, B. & Hofmann-Winkler, H. et al.​ (2021) 
  Frontiers in Immunology, 12.​ DOI: https://doi.org/10.3389/fimmu.2021.784989 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells​
  Becker, K. A.; Carpinteiro, A.; Hoffmann, M.; Pöhlmann, S.; Kornhuber, J. & Gulbins, E.​ (2021) 
  STAR Protocols, 2(1) pp. 100356​.​ DOI: https://doi.org/10.1016/j.xpro.2021.100356 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection​
  Winkler, M.; Claus, R.; Schilder, M.; Pöhlmann, S.; Coldewey, S.; Grundmann, J. & Fricke, T. et al.​ (2021) 
  Clinical Science, 135(24) pp. 2781​-2791​.​ DOI: https://doi.org/10.1042/CS20210666 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study​
  Tampe, D.; Hakroush, S.; Bösherz, M.-S.; Franz, J.; Hofmann-Winkler, H.; Pöhlmann, S. & Kluge, S. et al.​ (2021) 
  Frontiers in Medicine, 8.​ DOI: https://doi.org/10.3389/fmed.2021.644715 
  ​Details  DOI  PMID  PMC 

• 2021 | Journal Article | 
  ​ ​Dalbavancin: novel candidate for COVID-19 treatment​
  Hoffmann, M.; Jin, Y. & Pöhlmann, S.​ (2021) 
  Cell Research, 31(3) pp. 243​-244​.​ DOI: https://doi.org/10.1038/s41422-020-00459-5 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Mutation D614G increases SARS-CoV-2 transmission​
  Arora, P.; Pöhlmann, S. & Hoffmann, M.​ (2021) 
  Signal Transduction and Targeted Therapy, 6(1).​ DOI: https://doi.org/10.1038/s41392-021-00502-w 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection​
  Wettstein, L.; Weil, T.; Conzelmann, C.; Müller, J. A.; Groß, R.; Hirschenberger, M. & Seidel, A. et al.​ (2021) 
  Nature Communications, 12(1).​ DOI: https://doi.org/10.1038/s41467-021-21972-0 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination​
  Hammerschmidt, S. I.; Bosnjak, B.; Bernhardt, G.; Friedrichsen, M.; Ravens, I.; Dopfer-Jablonka, A. & Hoffmann, M. et al.​ (2021) 
  Cellular & Molecular Immunology, 18(10) pp. 2455​-2456​.​ DOI: https://doi.org/10.1038/s41423-021-00755-z 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance​
  Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Sidarovich, A.; Winkler, M. S. & Schulz, S. et al.​ (2021) 
  Cellular & Molecular Immunology, 18(11) pp. 2557​-2559​.​ DOI: https://doi.org/10.1038/s41423-021-00772-y 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency​
  Arora, P.; Rocha, C.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S. & Lier, M. et al.​ (2021) 
  Cellular & Molecular Immunology, 18(12) pp. 2673​-2675​.​ DOI: https://doi.org/10.1038/s41423-021-00779-5 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization​
  Lapuente, D.; Fuchs, J.; Willar, J.; Vieira Antão, A.; Eberlein, V.; Uhlig, N. & Issmail, L. et al.​ (2021) 
  Nature Communications, 12(1) art. 6871​.​ DOI: https://doi.org/10.1038/s41467-021-27063-4 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein​
  Arora, P.; Sidarovich, A.; Graichen, L.; Hörnich, B.; Hahn, A.; Hoffmann, M. & Pöhlmann, S.​ (2022) 
  PLoS One, 17(3) art. e0265453​.​ DOI: https://doi.org/10.1371/journal.pone.0265453 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Augmented neutralisation resistance of emerging omicron subvariants BA.2.12.1, BA.4, and BA.5​
  Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Cossmann, A.; Stankov, M. V & Jäck, H.-M. et al.​ (2022) 
  The Lancet Infectious Diseases, 22(8) pp. 1117​-1118​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00422-4 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Understanding Omicron: Transmissibility, immune evasion and antiviral intervention​
  Hoffmann, M.; Arora, P. & Pöhlmann, S.​ (2022) 
  Clinical and Translational Medicine, 12(5).​ DOI: https://doi.org/10.1002/ctm2.839 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Omicron sublineage BQ.1.1 resistance to monoclonal antibodies​
  Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Jäck, H.-M.; Pöhlmann, S. & Hoffmann, M.​ (2022) 
  The Lancet Infectious Diseases,.​ DOI: https://doi.org/10.1016/S1473-3099(22)00733-2 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic​
  Hoffmann, M.; Krüger, N.; Schulz, S.; Cossmann, A.; Rocha, C.; Kempf, A. & Nehlmeier, I. et al.​ (2022) 
  Cell, 185(3) pp. 447​-456.e11​.​ DOI: https://doi.org/10.1016/j.cell.2021.12.032 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants​
  Groß, R.; Zanoni, M.; Seidel, A.; Conzelmann, C.; Gilg, A.; Krnavek, D. & Erdemci-Evin, S. et al.​ (2022) 
  eBioMedicine, 75 art. S2352396421005557​.​ DOI: https://doi.org/10.1016/j.ebiom.2021.103761 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Primate Simplexviruses Differ in Tropism for Macaque Cells​
  Hofmann-Winkler, H.; Siregar, A. R.; Esiyok, N.; Rodríguez-Polo, I.; Gärtner, S.; Behr, R. & Pöhlmann, S. et al.​ (2022) 
  Microorganisms, 11(1) pp. 26​.​ DOI: https://doi.org/10.3390/microorganisms11010026 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​A Recombinant System and Reporter Viruses for Papiine Alphaherpesvirus 2​
  Rahman Siregar, A.; Gärtner, S.; Götting, J.; Stegen, P.; Kaul, A.; Schulz, T. F. & Pöhlmann, S. et al.​ (2022) 
  Viruses, 14(1) pp. 91​.​ DOI: https://doi.org/10.3390/v14010091 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Omicron: Master of immune evasion maintains robust ACE2 binding​
  Hoffmann, M.; Zhang, L. & Pöhlmann, S.​ (2022) 
  Signal Transduction and Targeted Therapy, 7(1) art. 118​.​ DOI: https://doi.org/10.1038/s41392-022-00965-5 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2​
  Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S.; Lier, M. & Schulz, S. et al.​ (2022) 
  Cellular & Molecular Immunology,.​ DOI: https://doi.org/10.1038/s41423-021-00811-8 
  ​Details  DOI 

• 2022 | Journal Article | Research Paper | 
  ​ ​Investigations on SARS-CoV-2 Susceptibility of Domestic and Wild Animals Using Primary Cell Culture Models Derived from the Upper and Lower Respiratory Tract​
  Färber, I.; Krüger, J.; Rocha, C.; Armando, F.; von Köckritz-Blickwede, M.; Pöhlmann, S. & Braun, A. et al.​ (2022) 
  Viruses, 14(4) pp. 828​.​ DOI: https://doi.org/10.3390/v14040828 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant​
  Heinen, N.; Marheinecke, C. S.; Bessen, C.; Blazquez-Navarro, A.; Roch, T.; Stervbo, U. & Anft, M. et al.​ (2022) 
  Frontiers in Immunology, 13 art. 1062210​.​ DOI: https://doi.org/10.3389/fimmu.2022.1062210 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article
  ​ ​Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2​
  Wagoner, J.; Herring, S.; Hsiang, T.-Y.; Ianevski, A.; Biering, S. B.; Xu, S. & Hoffmann, M. et al.​ (2022) 
  Microbiology Spectrum, 10(5) art. e03331-22​.​ DOI: https://doi.org/10.1128/spectrum.03331-22 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article
  ​ ​SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications​
  Schlör, A.; Hirschberg, S.; Amor, G. B.; Meister, T. L.; Arora, P.; Pöhlmann, S. & Hoffmann, M. et al.​ (2022) 
  Frontiers in Immunology, 13 art. 930975​.​ DOI: https://doi.org/10.3389/fimmu.2022.930975 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article | 
  ​ ​Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations​
  Jacobsen, H.; Strengert, M.; Maaß, H.; Ynga Durand, M. A.; Katzmarzyk, M.; Kessel, B. & Harries, M. et al.​ (2022) 
  Scientific Reports, 12(1) art. 19858​.​ DOI: https://doi.org/10.1038/s41598-022-22552-y 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article | Research Paper | 
  ​ ​Mutagenic Analysis of the HIV Restriction Factor Shiftless​
  Jäger, N.; Ayyub, S. A.; Korniy, N.; Peske, F.; Hoffmann, M.; Rodnina, M. V. & Pöhlmann, S.​ (2022) 
  Viruses, 14(7).​ DOI: https://doi.org/10.3390/v14071454 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1​
  Sidarovich, A.; Krüger, N.; Rocha, C.; Graichen, L.; Kempf, A.; Nehlmeier, I. & Lier, M. et al.​ (2022) 
  Viruses, 14(11) art. 2475​.​ DOI: https://doi.org/10.3390/v14112475 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article | 
  ​ ​The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant​
  Arora, P.; Zhang, L.; Rocha, C.; Graichen, L.; Nehlmeier, I.; Kempf, A. & Cossmann, A. et al.​ (2022) 
  International Journal of Molecular Sciences, 23(22) pp. 14057​.​ DOI: https://doi.org/10.3390/ijms232214057 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein​
  Budhadev, D.; Hooper, J.; Rocha, C.; Nehlmeier, I.; Kempf, A. M.; Hoffmann, M. & Krüger, N. et al.​ (2023) 
  JACS Au, 3(6) pp. 1755​-1766​.​ DOI: https://doi.org/10.1021/jacsau.3c00163 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation​
  Hoffmann, M.; Behrens, G. M N; Arora, P.; Kempf, A.; Nehlmeier, I.; Cossmann, A. & Manthey, L. et al.​ (2023) 
  The Lancet Infectious Diseases, 23(1) pp. 25​-28​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00792-7 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Neutralisation sensitivity of the SARS-CoV-2 XBB.1 lineage​
  Arora, P.; Cossmann, A.; Schulz, S. R; Ramos, G. M.; Stankov, M. V; Jäck, H.-M. & Behrens, G. M N et al.​ (2023) 
  The Lancet Infectious Diseases, 23(2) pp. 147​-148​.​ DOI: https://doi.org/10.1016/S1473-3099(22)00831-3 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Development of immortalized rhesus macaque kidney cells supporting infection with a panel of viruses​
  Reiter, S.; Gärtner, S.; Decker, K.; Pöhlmann, S. & Winkler, M.​ (2023) 
  PLoS One, 18(5) art. e0284048​.​ DOI: https://doi.org/10.1371/journal.pone.0284048 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Omicron subvariant BA.5 efficiently infects lung cells​
  Hoffmann, M.; Wong, L. Wong, Lok-Yin Roy; Arora, P.; Zhang, L.; Rocha, C.; Odle, A. & Nehlmeier, I. et al.​ (2023) 
  Nature Communications, 14(1).​ DOI: https://doi.org/10.1038/s41467-023-39147-4 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Neutralisation sensitivity of SARS-CoV-2 lineages EG.5.1 and XBB.2.3​
  Zhang, L.; Kempf, A.; Nehlmeier, I.; Cossmann, A.; Dopfer-Jablonka, A.; Stankov, M. V & Schulz, S. R et al.​ (2023) 
  The Lancet Infectious Diseases, 23(10) pp. e391​-e392​.​ DOI: https://doi.org/10.1016/S1473-3099(23)00547-9 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Systematical assessment of the impact of single spike mutations of SARS-CoV-2 Omicron sub-variants on the neutralization capacity of post-vaccination sera​
  Katzmarzyk, M.; Clesle, D. C.; van den Heuvel, J.; Hoffmann, M.; Garritsen, H.; Pöhlmann, S. & Jacobsen, H. et al.​ (2023) 
  Frontiers in Immunology, 14 art. 1288794​.​ DOI: https://doi.org/10.3389/fimmu.2023.1288794 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection​
  Metzdorf, K.; Jacobsen, H.; Greweling-Pils, M. C.; Hoffmann, M.; Lüddecke, T.; Miller, F. & Melcher, L. et al.​ (2023) 
  Viruses, 15(2).​ DOI: https://doi.org/10.3390/v15020271 
  ​Details  DOI 

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