Author Shipkova, Maria

1 to 77 of 77 Items
  • 2000 | Journal Article
    ​ ​Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and Emit​
    Shipkova, M.; Schutz, E.; Armstrong, V. W.; Niedmann, P. D.; Oellerich, M. & Wieland, E.​ (2000) 
    Clinical Chemistry, 46(3) pp. 365​-372​.​
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  • 2000 | Conference Paper
    ​ ​An ex vivo model to study the intestinal biotransformation of immunosuppressive drugs​
    Braun, F.; Christians, U.; Laabs, S.; Elias, K.; Shipkova, M.; Schutz, E. & Ringe, B.​ (2000)
    Transplantation Proceedings, 32(7) ​6th Congress of the Asian-Society-of-Transplantation​, SUNTEC CITY, SINGAPORE.
    New york​: Elsevier Science Inc. DOI: https://doi.org/10.1016/S0041-1345(00)01529-3 
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  • 2000 | Journal Article
    ​ ​Induction of cytokine release by the acyl glucuronide of mycophenolic acid: A link to side effects?​
    Wieland, E.; Shipkova, M.; Schellhaas, U.; Schütz, E.; Niedmann, P. D.; Armstrong, V. W. & Oellerich, M.​ (2000) 
    Clinical Biochemistry, 33(2) pp. 107​-113​.​ DOI: https://doi.org/10.1016/S0009-9120(99)00101-0 
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  • 2000 | Conference Paper
    ​ ​New strategies in GVHD prophylaxis​
    Kiehl, M. G.; Shipkova, M.; Basara, N.; Blau, W. I. & Fauser, A. A.​ (2000)
    Bone Marrow Transplantation, 25 pp. S16​-S19. ​2nd International Symposium on Transplantation and Gene Therapy​, IDAR OBERSTEIN, GERMANY.
    Basingstoke​: Nature Publishing Group. DOI: https://doi.org/10.1038/sj.bmt.1702346 
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  • 2000 | Conference Paper
    ​ ​An ex vivo model to study the intestinal biotransformation of immunosuppressives​
    Braun, F.; Christians, U.; Laabs, S.; Elias, K.; Shipkova, M.; Schutz, E. & Ringe, B.​ (2000)
    Transplantation Proceedings, 32(7) ​6th Congress of the Asian-Society-of-Transplantation​, SUNTEC CITY, SINGAPORE.
    New york​: Elsevier Science Inc. DOI: https://doi.org/10.1016/S0041-1345(00)01780-2 
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  • 2000 | Journal Article
    ​ ​Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring​
    Oellerich, M.; Shipkova, M.; Schutz, E.; Wieland, E.; Weber, L. T.; Tonshoff, B. & Armstrong, V. W.​ (2000) 
    Therapeutic Drug Monitoring, 22(1) pp. 20​-26​.​ DOI: https://doi.org/10.1097/00007691-200002000-00004 
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  • 2000 | Journal Article
    ​ ​Mycophenolate mofetil decreases endothelial prostaglandin E-2 in response to allogeneic T cells or cytokines​
    Blaheta, R. A.; Nelson, K.; Oppermann, E.; Leckel, K.; Harder, S.; Cinatl, J. & Weber, S. et al.​ (2000) 
    Transplantation Journal, 69(9) pp. 1977​-1981​.​ DOI: https://doi.org/10.1097/00007890-200005150-00044 
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  • 2000 | Journal Article | Letter Note
    ​ ​Evaluation of an immunoassay for mycophenolic acid​
    Schutz, E.; Shipkova, M.; Wieland, E.; Niedmann, P. D.; Armstrong, V. W. & Oellerich, M.​ (2000) 
    Therapeutic Drug Monitoring, 22(1) pp. 141​-142​.​ DOI: https://doi.org/10.1097/00007691-200002000-00030 
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  • 2000 | Conference Paper
    ​ ​The monoethylglycinexylidide (MEGX) test as a marker of hepatic dysfunction in septic patients with pneumonia​
    Igonin, A. A.; Armstrong, V. W.; Shipkova, M.; Kukes, V. G. & Oellerich, M.​ (2000)
    Clinical Chemistry and Laboratory Medicine (CCLM), 38(11) pp. 1125​-1128. ​European Meeting on Biomarkers of Organ Damage and Dysfunction​, CAMBRIDGE, ENGLAND.
    Berlin​: Walter De Gruyter & Co. DOI: https://doi.org/10.1515/CCLM.2000.169 
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  • 2000 | Journal Article
    ​ ​Mycophenolate mofetil in stem cell transplant patients in relation to plasma level of active metabolite​
    Kiehl, M. G.; Shipkova, M.; Basara, N.; Blau, I. W.; Schutz, E.; Armstrong, V. W. & Oellerich, M. et al.​ (2000) 
    Clinical Biochemistry, 33(3) pp. 203​-208​.​ DOI: https://doi.org/10.1016/S0009-9120(00)00053-9 
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  • 2001 | Journal Article | Letter Note
    ​ ​Quantification of mycophenolic acid in plasma samples collected during and immediately after intravenous administration of mycophenolate mofetil​
    Shipkova, M.; Armstrong, V. W.; Kiehl, M. G.; Niedmann, P. D.; Schutz, E.; Oellerich, M. & Wieland, E.​ (2001) 
    Clinical Chemistry, 47(8) pp. 1485​-1488​.​
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  • 2001 | Journal Article | Letter Note
    ​ ​Rapid and sensitive liquid chromatography-tandem mass spectrometry method for determination of monoethylglycinexylidide​
    Streit, F.; Niedmann, P. D.; Shipkova, M.; Armstrong, V. W. & Oellerich, M.​ (2001) 
    Clinical Chemistry, 47(10) pp. 1853​-1856​.​
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  • 2001 | Conference Abstract
    ​ ​Randomized multicenter prospective clinical trial on the efficacy of mycophenolate mofetil in comparison to methotrexate for the prophylaxis of acute GvHD in stem cell transplant recipients.​
    Kiehl, M. G.; Schaefer-Eckart, K.; Kienast, J.; Jenke, A.; Wandt, H.; Blau, I. W. & Shipkova, M. et al.​ (2001)
    Blood, 98(11) pp. 664A​-665A. 
    Washington​: Amer Soc Hematology.
    ​Details  WoS 
  • 2001 | Conference Paper
    ​ ​The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes​
    Shipkova, M.; Wieland, E.; Schutz, E.; Wiese, C. H.; Niedmann, P. D.; Oellerich, M. & Armstrong, V. W.​ (2001)
    Transplantation Proceedings, 33(1-2) pp. 1080​-1081. ​18th World Congress of the Transplantation-Society​, ROME, ITALY.
    New york​: Elsevier Science Inc. DOI: https://doi.org/10.1016/S0041-1345(00)02424-6 
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  • 2001 | Conference Paper
    ​ ​Monitoring of mycophenolic acid in pediatric renal transplant recipients​
    Armstrong, V. W.; Shipkova, M.; Schutz, E.; Weber, L. T.; Tonshoff, B. & Oellerich, M.​ (2001)
    Transplantation Proceedings, 33(1-2) pp. 1040​-1043. ​18th World Congress of the Transplantation-Society​, ROME, ITALY.
    New york​: Elsevier Science Inc. DOI: https://doi.org/10.1016/S0041-1345(00)02322-8 
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  • 2001 | Conference Paper
    ​ ​Preliminary report on the effect of xenoperfusion with human blood on cyclosporin A metabolism and cytochrome-P-4503A4-mRNA expression in a pig liver perfusion model​
    Wieland, E.; Shipkova, M.; Schütz, E.; Braun, F.; Niedmann, P.-D.; Armstrong, V. W. & Ringe, B. et al.​ (2001)
    Clinical Biochemistry, 34(1) pp. 53​-57. ​Analytical Conference 2000​, MUNICH, GERMANY.
    Oxford​: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S0009-9120(00)00203-4 
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  • 2001 | Journal Article
    ​ ​Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: Preliminary report​
    Shipkova, M.; Armstrong, V. W.; Kuypers, D.; Perner, F.; Fabrizi, V.; Holzer, H. & Wieland, E. et al.​ (2001) 
    Therapeutic Drug Monitoring, 23(6) pp. 717​-721​.​ DOI: https://doi.org/10.1097/00007691-200112000-00020 
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  • 2001 | Journal Article
    ​ ​Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes​
    Shipkova, M.; Strassburg, C. P.; Braun, F.; Streit, F.; Grone, H. J.; Armstrong, V. W. & Tukey, R. H. et al.​ (2001) 
    British Journal of Pharmacology, 132(5) pp. 1027​-1034​.​ DOI: https://doi.org/10.1038/sj.bjp.0703898 
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  • 2002 | Conference Abstract
    ​ ​Results of a 12 month multicenter trial investigating the kinetics of MPA and MPA-metabolites and the efficacy and side-effect profile of mycophenolate mofetil in renal transplant patients in view of MPA and MPA-metabolites.​
    Kuypers, D.; Vanrenterghem, Y.; Squifflet, J. P.; Mourad, M.; Abramowicz, D.; Oellerich, H. & Armstrong, V. W. et al.​ (2002)
    Journal of the American Society of Nephrology, 13 pp. 367A​-368A. 
    Philadelphia​: Lippincott Williams & Wilkins.
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  • 2002 | Journal Article
    ​ ​Comparison of the Emit immunoassay with HPLC for therapeutic drug monitoring of mycophenolic acid in pediatric renal-transplant recipients on mycophenolate mofetil therapy​
    Weber, L. T.; Shipkova, M.; Armstrong, V. W.; Wagner, N.; Schutz, E.; Mehls, O. & Zimmerhackl, L. B. et al.​ (2002) 
    Clinical Chemistry, 48(3) pp. 517​-525​.​
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  • 2002 | Journal Article
    ​ ​The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic acid in pediatric renal transplant recipients: A report of the German Study Group on Mycophenolate Mofetil Therapy​
    Weber, L. T.; Shipkova, M.; Armstrong, V. W.; Wagner, N.; Schutz, E.; Mehls, O. & Zimmerhackl, L. B. et al.​ (2002) 
    Journal of the American Society of Nephrology, 13(3) art. UNSP 1046-6673/1303-0759​.​
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  • 2002 | Journal Article
    ​ ​Atypical pharmacokinetics and metabolism of mycophenolic acid in a young kidney transplant recipient with impaired renal function​
    Wigger, M.; Armstrong, V. W.; Shipkova, M.; Wacke, R.; Nizze, H.; Streit, F. & von Ahsen, N. et al.​ (2002) 
    Therapeutic Drug Monitoring, 24(3) pp. 438​-443​.​ DOI: https://doi.org/10.1097/00007691-200206000-00019 
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  • 2002 | Journal Article
    ​ ​Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients​
    Shipkova, M.; Armstrong, V. W.; Weber, L. T.; Niedmann, P. D.; Wieland, E.; Haley, J. & Tonshoff, B. et al.​ (2002) 
    Therapeutic Drug Monitoring, 24(3) pp. 390​-399​.​ DOI: https://doi.org/10.1097/00007691-200206000-00011 
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  • 2002 | Journal Article
    ​ ​A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis​
    Maes, B.; Oellerich, M.; Ceuppens, J. L.; Armstrong, V. W.; Evenepoel, P.; Kuypers, D. & Messiaen, T. et al.​ (2002) 
    Nephrology Dialysis Transplantation, 17(5) pp. 923​-926​.​ DOI: https://doi.org/10.1093/ndt/17.5.923 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Conference Abstract
    ​ ​Pre-dose plums concentrations of the reactive acyl glucuronide of mycophenolic acid (AcMPAG) in kidney transplant recipients under therapy with mycophenolate mofeto (MMF), tacrolimus and steroids​
    Shipkova, M.; Maes, B.; Armstrong, V. W.; Wieland, E. & Oellerich, M.​ (2003)
    Therapeutic Drug Monitoring, 25(4) ​8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, BASEL, SWITZERLAND.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​Genotypic and phenotypic evaluations in connection with azathioprine toxicity.​
    Oellerich, M.; von Ahsen, N.; Shipkova, M. & Armstrong, V. W.​ (2003)
    Toxicological Sciences, 72 ​42nd Annual Meeting of the Society-of-Toxicology​, SALT LAKE CITY, UTAH.
    Oxford​: Oxford Univ Press.
    ​Details  WoS 
  • 2003 | Journal Article | Letter Note
    ​ ​Commentary on: Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods - Response​
    Shipkova, M.; Armstrong, V. W.; Wieland, E. & Oellerich, M.​ (2003) 
    Clinical Chemistry, 49(9) pp. 1551​-1552​.​
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​Quantification of plasma total MPA and free MPA 80 mass interferences in quantification of using liquid chromatography tandem mass cyclosporine using tandem mass spectrometry spectrometry​
    Streit, F.; Shipkova, M.; Armstrong, V. W. & Oellerich, M.​ (2003)
    Therapeutic Drug Monitoring, 25(4) ​8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, BASEL, SWITZERLAND.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​Relationship between plasma concentrations of mycophenolic acid (MPA) and its acyl glucuronide (AcMPAG) and intestinal damage in Wistar rats treated with mycophenolate mofetil (MMF)​
    Shipkova, M.; Voland, A.; Grone, H. J.; Armstrong, V. W.; Oellerich, M. & Wieland, E.​ (2003)
    Therapeutic Drug Monitoring, 25(4) ​8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, BASEL, SWITZERLAND.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​Phenotypic and genotypic analysis of thiopurine S-methyltransferase polymorphism in the Bulgarian population​
    Indiova, D.; Atanasova, S.; Shipkova, M.; Armstrong, V. W.; Oellerich, M. & Svinarov, D.​ (2003)
    Therapeutic Drug Monitoring, 25(4) ​8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, BASEL, SWITZERLAND.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2003 | Review
    ​ ​Acyl glucuronide drug metabolites: Toxicological and analytical implications​
    Shipkova, M.; Armstrong, V. W.; Oellerich, M.& Wieland, E.​ (2003)
    Therapeutic Drug Monitoring, 25​(1) pp. 1​-16​.​
    Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/00007691-200302000-00001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods​
    Shipkova, M.; Armstrong, V. W.; Wieland, E. & Oellerich, M.​ (2003) 
    Clinical Chemistry, 49(2) pp. 260​-268​.​ DOI: https://doi.org/10.1373/49.2.260 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Phenotypic and genotypic analysis of thiopurine S-methyltransferase polymorphism in the Bulgarian population​
    Indjova, D.; Atanasova, S.; Shipkova, M.; Armstrong, V. W.; Oellerich, M. & Svinarov, D.​ (2003) 
    Therapeutic Drug Monitoring, 25(5) pp. 631​-636​.​ DOI: https://doi.org/10.1097/00007691-200310000-00013 
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  • 2003 | Journal Article
    ​ ​Determination of thiopurine methyltransferase phenotype in isolated human erythrocytes using a new simple nonradioactive HPLC method​
    Indjova, D.; Shipkova, M.; Atanasova, S.; Niedmann, P. D.; Armstrong, V. W.; Svinarov, D. & Oellerich, M.​ (2003) 
    Therapeutic Drug Monitoring, 25(5) pp. 637​-644​.​ DOI: https://doi.org/10.1097/00007691-200310000-00014 
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  • 2003 | Journal Article
    ​ ​Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil​
    Kuypers, D.; Vanrenterghem, Y.; Squifflet, J. P.; Mourad, M.; Abramowicz, D.; Oellerich, M. & Armstrong, V. W. et al.​ (2003) 
    Therapeutic Drug Monitoring, 25(5) pp. 609​-622​.​ DOI: https://doi.org/10.1097/00007691-200310000-00011 
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  • 2003 | Journal Article
    ​ ​Erosive enterocolitis in mycophenolate mofetil-treated renal-transplant recipients with persistent afebrile diarrhea​
    Maes, B. D.; Dalle, I.; Geboes, K.; Oellerich, M.; Armstrong, V. W.; Evenepoel, P. & Geypens, B. et al.​ (2003) 
    Transplantation Journal, 75(5) pp. 665​-672​.​ DOI: https://doi.org/10.1097/01.TP.0000053753.43268.F0 
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  • 2003 | Journal Article
    ​ ​The immunosuppressive drug mycophenolate mofetil impairs the adhesion capacity of gastrointestinal tumour cells​
    Leckel, K.; Beecken, W. D.; Jonas, D.; Oppermann, E.; Coman, M. C.; Beck, K. F. & Cinatl, J. et al.​ (2003) 
    Clinical & Experimental Immunology, 134(2) pp. 238​-245​.​ DOI: https://doi.org/10.1046/j.1365-2249.2003.02290.x 
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  • 2004 | Journal Article
    ​ ​cDNA microarray analysis reveals new candidate genes possibly linked to side effects under mycophenolate mofetil therapy​
    Shipkova, M.; Spielbauer, B.; Voland, A.; Grone, H. J.; Armstrong, V. W.; Oellerich, M. & Wieland, E.​ (2004) 
    Transplantation Journal, 78(8) pp. 1145​-1152​.​ DOI: https://doi.org/10.1097/01.TP.0000137262.06252.05 
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  • 2004 | Journal Article
    ​ ​Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid​
    Streit, F.; Shipkova, M.; Armstrong, V. W. & Oellerich, M.​ (2004) 
    Clinical Chemistry, 50(1) pp. 152​-159​.​ DOI: https://doi.org/10.1373/clinchem.2003.024323 
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  • 2004 | Conference Paper
    ​ ​Analytic aspects of monitoring therapy with thiopurine medications​
    Armstrong, V. W.; Shipkova, M.; von Ahsen, N. & Oellerich, M.​ (2004)
    Therapeutic Drug Monitoring, 26(2) pp. 220​-226. ​8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, BASEL, SWITZERLAND.
    Philadelphia​: Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/00007691-200404000-00024 
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  • 2004 | Journal Article
    ​ ​Synergistic effects of sirolimus with cyclosporine and tacrolimus: Analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood​
    Barten, M. J.; Streit, F.; Boeger, M.; Dhein, S.; Tarnok, A.; Shipkova, M. & Armstrong, V. W. et al.​ (2004) 
    Transplantation Journal, 77(8) pp. 1154​-1162​.​ DOI: https://doi.org/10.1097/01.TP.0000120391.42712.E8 
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  • 2004 | Journal Article
    ​ ​Cyclosporin A absorption profiles in pediatric renal transplant recipients predict the risk of acute rejection​
    Weber, L. T.; Armstrong, V. W.; Shipkova, M.; Feneberg, R.; Wiesel, M.; Mehls, O. & Zimmerhackl, L. B. et al.​ (2004) 
    Therapeutic Drug Monitoring, 26(4) pp. 415​-424​.​ DOI: https://doi.org/10.1097/00007691-200408000-00012 
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  • 2004 | Journal Article
    ​ ​Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue​
    Shipkova, M.; Beck, H.; Voland, A.; Armstrong, V. W.; Grone, H. J.; Oellerich, M. & Wieland, E.​ (2004) 
    PROTEOMICS, 4(9) pp. 2728​-2738​.​ DOI: https://doi.org/10.1002/pmic.200300836 
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  • 2004 | Journal Article
    ​ ​Circulating cytokines as markers of systemic inflammatory response in severe community-acquired pneumonia​
    Igonin, A. A.; Armstrong, V. W.; Shipkova, M.; Lazareva, N. B.; Kukes, V. G. & Oellerich, M.​ (2004) 
    Clinical Biochemistry, 37(3) pp. 204​-209​.​ DOI: https://doi.org/10.1016/j.clinbiochem.2003.11.001 
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  • 2004 | Journal Article | Letter Note
    ​ ​Determination of thiopurine methyltransferase activity in isolated human erythrocytes does not reflect putative in vivo enzyme inhibition by sulfasalazine​
    Shipkova, M.; Niedmann, P. D.; Armstrong, V. W.; Oellerich, M. & Wieland, E.​ (2004) 
    Clinical Chemistry, 50(2) pp. 438​-441​.​ DOI: https://doi.org/10.1373/clinchem.2003.026096 
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  • 2005 | Conference Abstract
    ​ ​A prospective evaluation of the association between adverse drug reactions to azathioprine therapy and polymorphisms in the gene encoding inosine triphosphate pyrophosphatase​
    Armstrong, V. W.; Reinshagen, M.; von Ahsen, N.; Behrens, C.; Shipkova, M.; von Tirpitz, C. & Malchow, H. et al.​ (2005)
    Therapeutic Drug Monitoring, 27(2) ​9th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, Louisville, KY.
    Philadelphia​: Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/00007691-200504000-00148 
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  • 2005 | Journal Article
    ​ ​Analytic Aspects of Monitoring Therapy with Thiopurine Medications​
    Armstrong, V. W.; Shipkova, M.; von Ahsen, N. & Oellerich, M.​ (2005) 
    ChemInform, 36(2).​ DOI: https://doi.org/10.1002/chin.200502276 
    ​Details  DOI 
  • 2005 | Journal Article
    ​ ​Pharmacokinetics and bioavailability of mycophenolic acid after intravenous administration and oral administration of mycophenolate mofetil to heart transplant recipients​
    Armstrong, V. W.; Tenderich, G.; Shipkova, M.; Parsa, A.; Koerfer, R.; Schroder, H. & Oellerich, M.​ (2005) 
    Therapeutic Drug Monitoring, 27(3) pp. 315​-321​.​ DOI: https://doi.org/10.1097/01.ftd.0000163949.40686.0f 
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  • 2005 | Journal Article
    ​ ​Association of inosine triphosphatase 94C > A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study​
    von Ahsen, N.; Armstrong, V. W.; Behrens, C.; von Tirpitz, C.; Stallmach, A.; Herfarth, H. & Stein, J. et al.​ (2005) 
    Clinical Chemistry, 51(12) pp. 2282​-2288​.​ DOI: https://doi.org/10.1373/clinchem.2005.057158 
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  • 2005 | Journal Article
    ​ ​Mycophenolic acid interaction with cyclosporine and tacrolimus in vitro and in vivo - Evaluation of additive effects on rat blood lymphocyte function​
    Barten, M. J.; Shipkova, M.; Bartsch, P.; Dhein, S.; Streit, F.; Tarnok, A. & Armstrong, V. W. et al.​ (2005) 
    Therapeutic Drug Monitoring, 27(2) pp. 123​-131​.​ DOI: https://doi.org/10.1097/01.ftd.0000146874.11480.8a 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Conference Abstract
    ​ ​Cyclosporin determination with different immunoassays in four laboratories using routine patient samples from different transplant types: Performance of automated immunoassays and comparability to tandem mass spectrometry​
    Domke, I.; Shipkova, M.; Engelmayer, J.; Kheradmand, M.; Luthe, H.; Pou, L. & Streit, F. et al.​ (2006)
    Clinical Chemistry, 52(6) ​58th Annual Meeting of the American-Association-of-Clinical-Chemistry​, Chicago, IL.
    Washington​: Amer Assoc Clinical Chemistry.
    ​Details  WoS 
  • 2006 | Conference Abstract
    ​ ​Comparability between automated immunoassays and LC-MS/MS for tacrolimus determination using routine patient samples​
    Domke, I.; Vukovich, T.; Engelmayer, J.; Kheradmand, M.; Luthe, H.; Shipkova, M. & Streit, F. et al.​ (2006)
    Clinical Chemistry, 52(6) ​58th Annual Meeting of the American-Association-of-Clinical-Chemistry​, Chicago, IL.
    Washington​: Amer Assoc Clinical Chemistry.
    ​Details  WoS 
  • 2006 | Journal Article
    ​ ​Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a caucasian population​
    Shipkova, M.; Lorenz, K.; Oellerich, M.; Wieland, E. & von Ahsen, N.​ (2006) 
    Clinical Chemistry, 52(2) pp. 240​-247​.​ DOI: https://doi.org/10.1373/clinchem.2005.059501 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Conference Abstract
    ​ ​The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro​
    Feichtiger, H.; Wieland, E.; Armstrong, V. W. & Shipkova, M.​ (2007)
    Therapeutic Drug Monitoring, 29(4) pp. 539​-540. ​10th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, Nice, FRANCE.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2007 | Journal Article
    ​ ​Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats​
    Asif, A. R.; Armstrong, V. W.; Voland, A.; Wieland, E.; Oellerich, M. & Shipkova, M.​ (2007) 
    Biochimie, 89(3) pp. 393​-402​.​ DOI: https://doi.org/10.1016/j.biochi.2006.09.016 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial​
    Reinshagen, M.; Schuetz, E.; Armstrong, V. W.; Behrens, C.; von Tirpitz, C.; Stallmach, A. & Herfarth, H. et al.​ (2007) 
    Clinical Chemistry, 53(7) pp. 1306​-1314​.​ DOI: https://doi.org/10.1373/clinchem.2007.086215 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in Exon 6​
    Atanasova, S.; Shipkova, M.; Svinarov, D.; Mladenova, A.; Genova, M.; Wieland, E. & Oellerich, M. et al.​ (2007) 
    Therapeutic Drug Monitoring, 29(1) pp. 6​-10​.​ DOI: https://doi.org/10.1097/FTD.0b013e3180308554 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​Differential Proteomic Analysis of Lymphocytes Treated With Mycophenolic Acid Reveals Caspase 3-Induced Cleavage of Rho GDP Dissociation Inhibitor 2​
    Heller, T.; Asif, A. R.; Petrova, D. T.; Doncheva, Y.; Wieland, E.; Oellerich, M. & Shipkova, M. et al.​ (2009) 
    Therapeutic Drug Monitoring, 31(2) pp. 211​-217​.​
    ​Details  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​Regulation of IL2 and NUCB1 in Mononuclear Cells Treated With Acyl Glucuronide of Mycophenolic Acid Reveals Effects Independent of Inosine Monophosphate Dehydrogenase Inhibition​
    Petrova, D. T; Heller, T.; Hitt, R.; Wieland, E.; Oellerich, M.; Armstrong, V. W & Shipkova, M.​ (2009) 
    Therapeutic Drug Monitoring, 31(1) pp. 31​-41​.​ DOI: https://doi.org/10.1097/FTD.0b013e318192693e 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​Investigation of the Crossreactivity of Mycophenolic Acid Glucuronide Metabolites and of Mycophenolate Mofetil in the Cedia MPA Assay​
    Shipkova, M.; Schuetz, E.; Besenthal, I.; Fraunberger, P. & Wieland, E.​ (2010) 
    Therapeutic Drug Monitoring, 32(1) pp. 79​-85​.​
    ​Details  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro​
    Feichtiger, H.; Wieland, E.; Armstrong, V. W. & Shipkova, M.​ (2010) 
    Clinical Biochemistry, 43(1-2) pp. 208​-213​.​ DOI: https://doi.org/10.1016/j.clinbiochem.2009.08.023 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Review
    ​ ​Biomarkers as a Tool for Management of Immunosuppression in Transplant Patients​
    Wieland, E.; Olbricht, C. J.; Suesal, C.; Gurragchaa, P.; Boehler, T.; Israeli, M.& Sommerer, C. et al.​ (2010)
    Therapeutic Drug Monitoring, 32​(5) pp. 560​-572​.​
    Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/FTD.0b013e3181efb3d2 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Conference Abstract
    ​ ​Comparability and imprecision of eight frequently used commercially available immunoassays for therapeutic drug monitoring​
    Shipkova, M.; Petrova, D. T.; Rosler, A. E.; Orth, M.; Engelmayer, J.; Wieland, E. & Brandhorst, G. et al.​ (2011)
    Therapeutic Drug Monitoring, 33(4) ​12th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology​, Stuttgart, GERMANY.
    Philadelphia​: Lippincott Williams & Wilkins.
    ​Details  WoS 
  • 2011 | Conference Abstract
    ​ ​COMPARABILITY AND IMPRECISION OF EIGHT FREQUENTLY USED COMMERCIALLY AVAILABLE IMMUNOASSAYS FOR THERAPEUTIC DRUG MONITORING​
    Brandhorst, G.; Shipkova, M.; Rosler, E.; Orth, M.; Engelmayer, J.; Wieland, E. & Oellerich, M.​ (2011)
    Clinical Chemistry and Laboratory Medicine (CCLM), 49 
    Berlin​: Walter De Gruyter & Co.
    ​Details  WoS 
  • 2012 | Journal Article | Letter Note
    ​ ​Biomarkers in transplantation medicine: Guide to the next level in immunosuppressive therapy​
    Wieland, E.; Shipkova, M. & Oellerich, M.​ (2012) 
    Clinica Chimica Acta, 413(17-18).​ DOI: https://doi.org/10.1016/j.cca.2012.05.011 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Comparability and Imprecision of 8 Frequently Used Commercially Available Immunoassays for Therapeutic Drug Monitoring​
    Shipkova, M.; Petrova, D. T.; Rosler, A. E.; Orth, M.; Engelmayer, J.; Wieland, E. & Brandhorst, G. et al.​ (2014) 
    Therapeutic Drug Monitoring, 36(4) pp. 433​-441​.​
    ​Details  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Donor-Derived Cell-Free DNA Is a Novel Universal Biomarker for Allograft Rejection in Solid Organ Transplantation​
    Beck, J.; Oellerich, M.; Schulz, U.; Schauerte, V.; Reinhard, L.; Fuchs, U. & Knabbe, C. et al.​ (2015) 
    Transplantation Proceedings, 47(8) pp. 2400​-2403​.​ DOI: https://doi.org/10.1016/j.transproceed.2015.08.035 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Therapeutic Drug Monitoring of Everolimus: A Consensus Report​
    Shipkova, M.; Hesselink, D. A.; Holt, D. W.; Billaud, E. M.; van Gelder, T.; Kunicki, P. K. & Brunet, M. et al.​ (2016) 
    Therapeutic Drug Monitoring, 38(2) pp. 143​-169​.​
    ​Details  PMID  PMC  WoS 
  • 2016 | Review
    ​ ​Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice: Recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Immunosuppressive Drug Scientific Committee​
    Seger, C.; Shipkova, M.; Christians, U.; Billaud, E. M.; Wang, P.; Holt, D. W.& Brunet, M. et al.​ (2016)
    Therapeutic Drug Monitoring, 38​(2) pp. 170​-189​.​
    Lippincott Williams & Wilkins.
    ​Details  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Analytical evaluation of a real-time PCR-based DNA demethylation assay to assess the frequency of naturally occurring regulatory T cells in peripheral blood​
    Metzker, M.; Shipkova, M.; von Ahsen, N. ; Andag, R.; Abe, M.; Canzler, O. & Klett, C. et al.​ (2016) 
    Clinical Biochemistry, 49(15) pp. 1173​-1180​.​ DOI: https://doi.org/10.1016/j.clinbiochem.2016.05.019 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Therapeutic Drug Monitoring of Everolimus​
    Shipkova, M.; Hesselink, D. A.; Holt, D. W.; Billaud, E. M.; van Gelder, T.; Kunicki, P. K. & Brunet, M. et al.​ (2016) 
    Therapeutic Drug Monitoring, 38(2) pp. 143​-169​.​ DOI: https://doi.org/10.1097/FTD.0000000000000260 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice​
    Seger, C.; Shipkova, M.; Christians, U.; Billaud, E. M.; Wang, P.; Holt, D. W. & Brunet, M. et al.​ (2016) 
    Therapeutic Drug Monitoring, 38(2) pp. 170​-189​.​ DOI: https://doi.org/10.1097/FTD.0000000000000269 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation​
    Brunet, M.; Shipkova, M.; van Gelder, T.; Wieland, E.; Sommerer, C.; Budde, K. & Haufroid, V. et al.​ (2016) 
    Therapeutic Drug Monitoring, 38 pp. S1​-S20​.​ DOI: https://doi.org/10.1097/FTD.0000000000000287 
    ​Details  DOI  PMID  PMC  WoS 
  • 2018 | Journal Article
    ​ ​Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate​
    Rieger, H.; Schmidt, P.; Schaeffeler, E.; Abe, M.; Schiffhauer, M.; Schwab, M. & von Ahsen, N.  et al.​ (2018) 
    Clinical Chemistry and Laboratory Medicine, 56(5) pp. 803​-809​.​ DOI: https://doi.org/10.1515/cclm-2017-0670 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Absolute quantification of donor‐derived cell‐free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study​
    Oellerich, M.; Shipkova, M.; Asendorf, T. ; Walson, P. D.; Schauerte, V.; Mettenmeyer, N. & Kabakchiev, M. et al.​ (2019) 
    American Journal of Transplantation, 19(11) pp. 3087​-3099​.​ DOI: https://doi.org/10.1111/ajt.15416 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Time-Dependent Apparent Increase in dd-cfDNA Percentage in Clinically Stable Patients Between One and Five Years Following Kidney Transplantation​
    Schütz, E. ; Asendorf, T. ; Beck, J.; Schauerte, V.; Mettenmeyer, N.; Shipkova, M. & Wieland, E. et al.​ (2020) 
    Clinical Chemistry, 66(10) pp. 1290​-1299​.​ DOI: https://doi.org/10.1093/clinchem/hvaa175 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives—An Interview in Honor of Professor Charles Pippenger​
    Wong, S. H.; Marquet, P.; Cattaneo, D.; Svinarov, D.; Bergan, S.; Walson, P. & Vinks, A. A. et al.​ (2021) 
    Therapeutic Drug Monitoring, 43(6) pp. 719​-727​.​ DOI: https://doi.org/10.1097/FTD.0000000000000932 
    ​Details  DOI 

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