Author Zafar, Saima

1 to 36 of 36 Items
  • 2011 | Journal Article
    ​ ​Proteomics Approach to Identify the Interacting Partners of Cellular Prion Protein and Characterization of Rab7a Interaction in Neuronal Cells​
    Zafar, S.; von Ahsen, N.; Oellerich, M.; Zerr, I.; Schulz-Schaeffer, W. J.; Armstrong, V. W. & Asif, A. R.​ (2011) 
    Journal of Proteome Research, 10(7) pp. 3123​-3135​.​ DOI: https://doi.org/10.1021/pr2001989 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Conference Abstract
    ​ ​Interactive role of Arf1 and Alpha tubulin-1 protein during the intracellular transportation of PrPc​
    Zafar, S.​ (2012)
    Prion, 6 
    Austin​: Landes Bioscience.
    ​Details  WoS 
  • 2013 | Conference Abstract
    ​ ​Analysis of sporadic Creutzfeldt-Jakob disease patients cerebrospinal fluid by real-time quaking-induced conversion​
    Cramm, M.; Schmitz, M.; Karch, A.; Zafar, S.; Schroeder, B.; Raeber, A. & Kuhn, F. et al.​ (2013)
    Prion, 7 pp. 54​-55. 
    Austin​: Landes Bioscience.
    ​Details  WoS 
  • 2013 | Journal Article
    ​ ​PrP mRNA and protein expression in brain and PrPc in CSF in Creutzfeldt-Jakob disease MM1 and VV2​
    Llorens, F.; Ansoleaga, B.; Garcia-Esparcia, P.; Zafar, S.; Grau-Rivera, O.; Lopez-Gonzalez, I. & Blanco, R. et al.​ (2013) 
    Prion, 7(5) pp. 383​-393​.​ DOI: https://doi.org/10.4161/pri.26416 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Conference Abstract
    ​ ​Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease​
    Llorens, F.; Zafar, S.; Ansoleaga, B.; Shafiq, M. ; Blanco, R.; Carmona, M. & Gelpi, E. et al.​ (2014)
    Prion, 8 
    Austin​: Landes Bioscience.
    ​Details  WoS 
  • 2014 | Journal Article
    ​ ​Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrPC for the cytoskeleton​
    Schmitz, M.; Zafar, S.; Silva, C. J. & Zerr, I.​ (2014) 
    Prion, 8(6) pp. 381​-386​.​ DOI: https://doi.org/10.4161/19336896.2014.983746 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | 
    ​ ​Subtype and regional-specific neuroinflammation in sporadic Creutzfeldt-Jakob disease​
    Llorens, F.; Lopez-Gonzalez, I.; Thuene, K.; Carmona, M.; Zafar, S.; Andreoletti, O. & Zerr, I. et al.​ (2014) 
    Frontiers in Aging Neuroscience, 6 art. 198​.​ DOI: https://doi.org/10.3389/fnagi.2014.00198 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease​
    Douet, J. Y.; Zafar, S.; Perret-Liaudet, A.; Lacroux, C.; Lugan, S.; Aron, N. & Cassard, H. et al.​ (2014) 
    EMERGING INFECTIOUS DISEASES, 20(1) pp. 114​-117​.​ DOI: https://doi.org/10.3201/eid2001.130353 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases​
    Schmitz, M.; Luellmann, K.; Zafar, S.; Ebert, E.; Wohlhage, M.; Oikonomou, P. & Schlomm, M. et al.​ (2014) 
    Neurobiology of Aging, 35(5) pp. 1177​-1188​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2013.11.010 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD​
    Llorens, F.; Kruse, N.; Schmitz, M.; Shafiq, M.; Gomes da Cunha, J. E.; Gotzman, N.   & Zafar, S. et al.​ (2015) 
    Journal of Neurology, 262(10) pp. 2305​-2311​.​ DOI: https://doi.org/10.1007/s00415-015-7837-x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Application of capillary immunoelectrophoresis revealed an age- and gender-dependent regulated expression of PrPC in liver​
    Arora, A. S. ; Zafar, S.; Kollmar, O.; Llorens, F.; Tahir, W.; Vanselow, S. & Kumar, P. et al.​ (2015) 
    Electrophoresis, 36(24) pp. 3026​-3033​.​ DOI: https://doi.org/10.1002/elps.201500244 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage​
    Zafar, S.; Schmitz, M.; Younus, N.; Tahir, W.; Shafiq, M.; Llorens, F. & Ferrer, I. et al.​ (2015) 
    Journal of Molecular Neuroscience, 56(2) pp. 329​-348​.​ DOI: https://doi.org/10.1007/s12031-015-0544-3 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions​
    Ramljak, S.; Schmitz, M.; Zafar, S.; Wrede, A.; Schenkel, S.; Asif, A. R. & Carimalo, J. et al.​ (2015) 
    Experimental Neurology, 271 pp. 155​-167​.​ DOI: https://doi.org/10.1016/j.expneurol.2015.04.025 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy​
    Schmitz, M.; Hermann, P.; Oikonomou, P.; Stoeck, K.; Ebert, E.; Poliakova, T. & Schmidt, C. D. et al.​ (2015) 
    Neurobiology of Aging, 36(9) pp. 2597​-2606​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2015.05.013 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases​
    Cramm, M.; Schmitz, M.; Karch, A.; Zafar, S.; Varges, D. A.; Mitrova, E. & Schroeder, B. et al.​ (2015) 
    Molecular Neurobiology, 51(1) pp. 396​-405​.​ DOI: https://doi.org/10.1007/s12035-014-8709-6 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Conference Abstract
    ​ ​Prion protein interactome: Identifying novel targets in rapidly progressive Alzheimer's disease​
    Shafiq, M.; Zafar, S.; Younas, N.; Schmitz, M.; Ferrer, I. & Zerr, I.​ (2016)
    Prion, 10 
    Philadelphia​: Taylor & Francis Inc.
    ​Details  WoS 
  • 2016 | Conference Abstract
    ​ ​Genetic prion diseases​
    Zerr, I.; Schmitz, M.; Zafar, S. & Llorens, F.​ (2016)
    Prion, 10 
    Philadelphia​: Taylor & Francis Inc.
    ​Details  WoS 
  • 2016 | Conference Abstract
    ​ ​Early response of Cofilin1 pathway in Creutzfeldt Jakob disease​
    Younas, N.; Zafar, S.; Shafiq, M.; Tahir, W.; Schmitz, M.; Ferrer, I. & Andreoletti, O. et al.​ (2016)
    Prion, 10 pp. S102​-S103. 
    Philadelphia​: Taylor & Francis Inc.
    ​Details  WoS 
  • 2016 | Journal Article | 
    ​ ​Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients​
    Schmitz, M.; Llorens, F.; Pracht, A.; Thom, T.; Correia, A. ; Zafar, S. & Ferrer, I. et al.​ (2016) 
    Aging, 8(11) pp. 2927​-2935​.​ DOI: https://doi.org/10.18632/aging.101101 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | 
    ​ ​Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie​
    Schmitz, M.; Cramm, M.; Llorens, F.; Candelise, N. ; Mueller-Cramm, D.; Varges, D. A. & Schulz-Schaeffer, W. J. et al.​ (2016) 
    Scientific Reports, 6 art. 28711​.​ DOI: https://doi.org/10.1038/srep28711 
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  • 2017 | Journal Article
    ​ ​Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease​
    Zafar, S.; Younas, N.; Correia, S. ; Shafiq, M.; Tahir, W.; Schmitz, M. & Ferrer, I. et al.​ (2017) 
    Molecular Neurobiology, 54(1) pp. 697​-709​.​ DOI: https://doi.org/10.1007/s12035-016-9694-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms.​
    Garcia-Esparcia, P.; López-González, I.; Grau-Rivera, O.; García-Garrido, M. F.; Konetti, A.; Llorens, F. & Zafar, S. et al.​ (2017) 
    Frontiers in neurology, 8 art. 89​.​ DOI: https://doi.org/10.3389/fneur.2017.00089 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article | 
    ​ ​Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells​
    Zafar, S.; Behrens, C.; Dihazi, H.; Schmitz, M.; Zerr, I.; Schulz-Schaeffer, W. J. & Ramljak, S. et al.​ (2017) 
    Cell Death and Disease, 8 art. e2557​.​ DOI: https://doi.org/10.1038/cddis.2016.384 
    ​Details  DOI  PMID  PMC  WoS 
  • 2018 | Book Chapter
    ​ ​Cerebrospinal fluid in Creutzfeldt–Jakob disease​
    Zerr, I.; Zafar, S.; Schmitz, M.& Llorens, F.​ (2018)
    In: Cerebrospinal Fluid in Neurologic Disorders pp. 115​-124. ​Elsevier. DOI: https://doi.org/10.1016/B978-0-12-804279-3.00008-3 
    ​Details  DOI 
  • 2019 | Book Chapter
    ​ ​Therapies for prion diseases​
    Zafar, S.; Noor, A.& Zerr, I.​ (2019)
    In: Psychopharmacology of Neurologic Disease pp. 47​-58. ​Elsevier. DOI: https://doi.org/10.1016/B978-0-444-64012-3.00004-6 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease​
    Cheng, L.; Quek, C.; Li, X.; Bellingham, S. A.; Ellett, L. J.; Shambrook, M. & Zafar, S. et al.​ (2021) 
    Communications Biology, 4(1).​ DOI: https://doi.org/10.1038/s42003-021-01868-x 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease​
    Shafiq, M.; Zafar, S.; Younas, N.; Noor, A.; Puig, B.; Altmeppen, H. C. & Schmitz, M. et al.​ (2021) 
    Molecular Neurodegeneration, 16(1) art. 11​.​ DOI: https://doi.org/10.1186/s13024-021-00422-x 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo​
    Thom, T.; Schmitz, M.; Fischer, A.; Correia, A.; Correia, S.; Llorens, F. & Pique, A. et al.​ (2021) 
    Movement Disorders, 37(1) art. mds.28774​.​ DOI: https://doi.org/10.1002/mds.28774 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | 
    ​ ​Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease​
    Noor, A.; Zafar, S.; Shafiq, M.; Younas, N.; Siegert, A.; Mann, F. A. & Kruss, S. et al.​ (2021) 
    Molecular Neurobiology, 59(1) pp. 17​-34​.​ DOI: https://doi.org/10.1007/s12035-021-02566-9 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients​
    Zafar, S.; Noor, A.; Younas, N.; Shafiq, M.; Schmitz, M.; Wurster, I. & Brockmann, K. et al.​ (2022) 
    International Journal of Molecular Sciences, 23(22) pp. 14166​.​ DOI: https://doi.org/10.3390/ijms232214166 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​The Role of Tau Proteoforms in Health and Disease​
    Waheed, Z.; Choudhary, J.; Jatala, F. H.; Fatimah, F.; Noor, A.; Zerr, I. & Zafar, S.​ (2023) 
    Molecular Neurobiology,.​ DOI: https://doi.org/10.1007/s12035-023-03387-8 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​Genetic Variants Associated with the Age of Onset Identified by Whole-Exome Sequencing in Fatal Familial Insomnia​
    Thüne, K.; Schmitz, M.; Wiedenhöft, J.; Shomroni, O.; Göbel, S.; Bunck, T. & Younas, N. et al.​ (2023) 
    Cells, 12(16) pp. 2053​.​ DOI: https://doi.org/10.3390/cells12162053 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology​
    Younas, N. ; Zafar, S.; Saleem, T.; Fernandez Flores, L. C.; Younas, A.; Schmitz, M. & Zerr, I.​ (2023) 
    Cell & Bioscience, 13(1).​ DOI: https://doi.org/10.1186/s13578-023-01164-7 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies​
    Schmitz, M. ; Candelise, N.; Canaslan, S.; Altmeppen, H. C.; Matschke, J.; Glatzel, M. & Younas, N. et al.​ (2023) 
    Translational Neurodegeneration, 12(1) art. 12​.​ DOI: https://doi.org/10.1186/s40035-023-00342-4 
    ​Details  DOI 
  • 2024 | Journal Article
    ​ ​Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration​
    Zafar, S.; Fatima, S. I.; Schmitz, M. & Zerr, I.​ (2024) 
    Biomolecules, 14(1) pp. 118​.​ DOI: https://doi.org/10.3390/biom14010118 
    ​Details  DOI 
  • 2024 | Journal Article
    ​ ​A systemic analysis of Creutzfeldt Jakob disease cases in Asia​
    Rasheed, U.; Khan, S.; Khalid, M.; Noor, A. & Zafar, S.​ (2024) 
    Prion, 18(1) pp. 11​-27​.​ DOI: https://doi.org/10.1080/19336896.2024.2311950 
    ​Details  DOI 

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