Author Friede, Tim
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2012 | Journal Article
An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection
Parsons, N.; Friede, T.; Todd, S.; Marquez, E. V.; Chataway, J.; Nicholas, R. & Stallard, N. (2012)
Computational Statistics & Data Analysis, 56(5) pp. 1150-1160. DOI: https://doi.org/10.1016/j.csda.2010.10.027
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2012 | Journal Article
Blinded continuous monitoring of nuisance parameters in clinical trials
Friede, T. & Miller, F. (2012)
Journal of the Royal Statistical Society Series C (Applied Statistics), 61 pp. 601-618. DOI: https://doi.org/10.1111/j.1467-9876.2011.01029.x
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2012 | Journal Article |
Safety and Efficacy of the ACE-Inhibitor Ramipril in Alport Syndrome: The Double-Blind, Randomized, Placebo-Controlled, Multicenter Phase III EARLY PRO-TECT Alport Trial in Pediatric Patients
Gross, O.; Friede, T.; Hilgers, R.; Görlitz, A.; Gavénis, K.; Ahmed, R. & Dürr, U. (2012)
ISRN Pediatrics, 2012 pp. 1-6. DOI: https://doi.org/10.5402/2012/436046
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2012 | Review |
Time-patterns of annualized relapse rates in randomized placebo-controlled clinical trials in relapsing multiple sclerosis: A systematic review and meta-analysis
Nicholas, R.; Straube, S.; Schmidli, H.; Pfeiffer, S.& Friede, T. (2012)
Multiple Sclerosis Journal, 18(9) pp. 1290-1296.
Sage Publications Ltd. DOI: https://doi.org/10.1177/1352458511435715
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2012 | Conference Paper
A conditional error function approach for subgroup selection in adaptive clinical trials
Friede, T.; Parsons, N. & Stallard, N. (2012)
Statistics in Medicine, 31(30) pp. 4309-4320. 32nd Annual Conference of the International-Society-for-Clinical-Biostatistics, Ontario, CANADA.
Hoboken: Wiley-blackwell. DOI: https://doi.org/10.1002/sim.5541
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2012 | Journal Article
Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy
Gross, O.; Licht, C.; Anders, H.-J.; Hoppe, B.; Beck, B.; Toenshoff, B. & Hoecker, B. et al. (2012)
Kidney International, 81(5) pp. 494-501. DOI: https://doi.org/10.1038/ki.2011.407
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2012 | Conference Paper
Considerations on what constitutes a 'qualified statistician' in regulatory guidelines
Gerlinger, C.; Edler, L.; Friede, T.; Kieser, M.; Nakas, C. T.; Schumacher, M. & Seldrup, J. et al. (2012)
Statistics in Medicine, 31(11-12) pp. 1303-1305. 31st Annual Conference of the International-Society-for-Clinical-Biostatistics, Montpellier, FRANCE.
Hoboken: Wiley-blackwell. DOI: https://doi.org/10.1002/sim.4345
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2012 | Review
Calcineurin Inhibitor Sparing With Mycophenolate Mofetil in Liver Transplantion: A Systematic Review of Randomized Controlled Trials
Goralczyk, A. D.; Bari, N.; Abu-Ajaj, W.; Lorf, T.; Ramadori, G.; Friede, T.& Obed, A. (2012)
American Journal of Transplantation, 12(10) pp. 2601-2607.
Wiley-blackwell. DOI: https://doi.org/10.1111/j.1600-6143.2012.04157.x
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2013 | Journal Article
A conditional error function approach for subgroup selection in adaptive clinical trials (vol 31, pg 4309, 2012)
Friede, T.; Parsons, N. & Stallard, N. (2013)
Statistics in Medicine, 32(14) pp. 2513-2514. DOI: https://doi.org/10.1002/sim.5759
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2013 | Conference Abstract
Using the internet in the management of multiple sclerosis: an overview of the evidence available
Schilling, J.; Friede, T. & Straube, S. (2013)
Multiple Sclerosis Journal, 19(11) pp. 302-303. 29th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis / 18th Annual Conference of Rehabilitation in MS, Copenhagen, DENMARK.
London: Sage Publications Ltd.
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2013 | Conference Abstract
Comparison of disability scores and annualised relapse rates as trial outcomes in randomized, placebo controlled trials in relapsing multiple sclerosis: a systematic review
Roever, C. ; Nicholas, R.; Steinvorth, S.; Straube, S. & Friede, T. (2013)
Multiple Sclerosis Journal, 19(11) pp. 498-499. 29th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis / 18th Annual Conference of Rehabilitation in MS, Copenhagen, DENMARK.
London: Sage Publications Ltd.
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2013 | Journal Article |
Study protocol: improving patient choice in treating Low back pain (IMPACT-LBP): a randomised controlled trial of a decision support package for use in physical therapy (vol 12, 52, 2011)
Patel, S.; Brown, S.; Friede, T.; Griffiths, F.; Lord, J.; Ngunjiri, A. & Thistlethwaite, J. et al. (2013)
BMC Musculoskeletal Disorders, 14 art. 158. DOI: https://doi.org/10.1186/1471-2474-14-158
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2013 | Journal Article
Blinded sample size re-estimation in superiority and noninferiority trials: bias versus variance in variance estimation
Friede, T. & Kieser, M. (2013)
Pharmaceutical Statistics, 12(3) pp. 141-146. DOI: https://doi.org/10.1002/pst.1564
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2013 | Journal Article
Cross cultural evaluation of the Warwick-Edinburgh mental well-being scale (WEMWBS) -a mixed methods study
Taggart, F.; Friede, T.; Weich, S.; Clarke, A.; Johnson, M. A. & Stewart-Brown, S. (2013)
Health and Quality of Life Outcomes, 11 art. 27. DOI: https://doi.org/10.1186/1477-7525-11-27
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2013 | Journal Article
Assessment of statistical significance and clinical relevance
Kieser, M.; Friede, T. & Gondan, M. (2013)
Statistics in Medicine, 32(10) pp. 1707-1719. DOI: https://doi.org/10.1002/sim.5634
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2013 | Review
Systematic Review of Randomized Controlled Trials of Clinical Prediction Rules for Physical Therapy in Low Back Pain
Patel, S.; Psychol, C.; Friede, T.; Froud, R.; Evans, D. W.& Underwood, M. (2013)
Spine, 38(9) pp. 762-769.
Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/BRS.0b013e31827b158f
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2013 | Journal Article | Research Paper
Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα
Kruss, S.; Erpenbeck, L.; Amschler, K.; Mundinger, T. A. ; Boehm, H.; Helms, H.-J. & Friede, T. et al. (2013)
ACS Nano, 7(11) pp. 9984-9996. DOI: https://doi.org/10.1021/nn403923h
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2013 | Journal Article
Robustness of methods for blinded sample size re-estimation with overdispersed count data
Schneider, S.; Schmidli, H. & Friede, T. (2013)
Statistics in Medicine, 32(21) pp. 3623-3635. DOI: https://doi.org/10.1002/sim.5800
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2013 | Journal Article
Blinded sample size re-estimation for recurrent event data with time trends
Schneider, S.; Schmidli, H. & Friede, T. (2013)
Statistics in Medicine, 32(30) pp. 5448-5457. DOI: https://doi.org/10.1002/sim.5977
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2013 | Journal Article |
Explaining temporal trends in annualised relapse rates in placebo groups of randomised controlled trials in relapsing multiple sclerosis: systematic review and meta-regression
Steinvorth, S. M.; Roever, C. ; Schneider, S.; Nicholas, R.; Straube, S. & Friede, T. (2013)
Multiple Sclerosis Journal, 19(12) pp. 1580-1586. DOI: https://doi.org/10.1177/1352458513481009
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