Author Schuberth, Ingrid

• 2000 | Journal Article
  ​ ​Preparation of a new carboranyl lactoside for the treatment of cancer by boron neutron capture therapy: Synthesis and toxicity of fluoro carboranyl glycosides for in vivo F-19-NMR spectroscopy​
  Tietze, L. F. ; Bothe, U.   & Schuberth, I.​ (2000) 
  Chemistry - A European Journal, 6(5) pp. 836​-842​.​ DOI: https://doi.org/10.1002/(SICI)1521-3765(20000303)6:5<836::AID-CHEM836>3.0.CO;2-8 
  ​Details  DOI  PMID  PMC  WoS 

• 2003 | Journal Article
  ​ ​Novel Carboranyl C-Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy.​
  Tietze, L. F.; Griesbach, U.; Schuberth, I.; Bothe, U.; Marra, A. & Dondoni, A.​ (2003) 
  ChemInform, 34(28).​ DOI: https://doi.org/10.1002/chin.200328212 
  ​Details  DOI 

• 2005 | Journal Article
  ​ ​A Diels—Alder Reaction for the Total Synthesis of the Novel Antibiotic Antitumor Agent Mensacarcin (I).​
  Tietze, L. F.; Guentner, C.; Gericke, K. M.; Schuberth, I. & Bunkoczi, G.​ (2005) 
  ChemInform, 36(43).​ DOI: https://doi.org/10.1002/chin.200543222 
  ​Details  DOI 

• 2006 | Journal Article
  ​ ​Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry​
  Tietze, L. F.; Krewer, B.; Frauendorf, H.; Major, F. & Schuberth, I.​ (2006) 
  Angewandte Chemie International Edition, 45(39) pp. 6570​-6574​.​ DOI: https://doi.org/10.1002/anie.200600935 
  ​Details  DOI  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Antitumor agents: Development of highly potent glycosidic duocarmycin analogues for selective cancer therapy​
  Tietze, L. F.; Major, F. & Schuberth, I.​ (2006) 
  Angewandte Chemie International Edition, 45(39) pp. 6574​-6577​.​ DOI: https://doi.org/10.1002/anie.200600936 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Journal Article
  ​ ​Synthesis of highly functionalized anthraquinones and evaluation of their antitumor activity​
  Tietze, L. F.; Gericke, K. M. & Schuberth, I.​ (2007) 
  European Journal of Organic Chemistry,(27) pp. 4563​-4577​.​ DOI: https://doi.org/10.1002/ejoc.200700418 
  ​Details  DOI  WoS 

• 2007 | Journal Article
  ​ ​Novel strategies for the synthesis of anthrapyran antibiotics: discovery of a new antitumor agent and total synthesis of (S)-espicufolin​
  Tietze, L. F.; Gericke, K. M.; Singidi, R. R. & Schuberth, I.​ (2007) 
  Organic & Biomolecular Chemistry, 5(8) pp. 1191​-1200​.​ DOI: https://doi.org/10.1039/b700838d 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Journal Article
  ​ ​Selective treatment of cancer: Synthesis, biological evaluation and structural elucidation of novel analogues of the antibiotic CC-1065 and the duocarmycins​
  Tietze, L. F.; Major, F.; Schuberth, I.; Spiegl, D. A.; Krewer, B.; Maksimenka, K. & Bringmann, G. et al.​ (2007) 
  Chemistry - A European Journal, 13(16) pp. 4396​-4409​.​ DOI: https://doi.org/10.1002/chem.200700113 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Duocarmycin-based prodrugs for cancer prodrug monotherapy​
  Tietze, L. F.; Schuster, H. J.; Schmuck, K.; Schuberth, I. & Alves, F. ​ (2008) 
  Bioorganic & Medicinal Chemistry, 16(12) pp. 6312​-6318​.​ DOI: https://doi.org/10.1016/j.bmc.2008.05.009 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy​
  Tietze, L. F.; von Hof, J. M.; Krewer, B.; Mueller, M.; Major, F.; Schuster, H. J. & Schuberth, I. et al.​ (2008) 
  ChemMedChem, 3(12) pp. 1946​-1955​.​ DOI: https://doi.org/10.1002/cmdc.200800250 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article | 
  ​ ​Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug monotherapy of cancer​
  Tietze, L. F.; Panknin, O.; Krewer, B.; Major, F. & Schuberth, I.​ (2008) 
  International Journal of Molecular Sciences, 9(5) pp. 821​-837​.​ DOI: https://doi.org/10.3390/ijms9050821 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article | 
  ​ ​Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065​
  Tietze, L. F.; Krewer, B.; von Hof, J. M.; Frauendorf, H. & Schuberth, I.​ (2009) 
  Toxins, 1(2) pp. 134​-150​.​ DOI: https://doi.org/10.3390/toxins1020134 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article
  ​ ​CD-Spectroscopy As a Powerful Tool for Investigating the Mode of Action of Unmodified Drugs in Live Cells​
  Tietze, L. F.; Krewer, B.; Major, F. & Schuberth, I.​ (2009) 
  Journal of the American Chemical Society, 131(36) pp. 13031​-13036​.​ DOI: https://doi.org/10.1021/ja902767f 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article | 
  ​ ​A comprehensive view on 4-methyl-2-quinazolinamine, a new microbial alkaloid from Streptomyces of TCM plant origin​
  Vollmar, D.; Thorn, A.; Schuberth, I. & Grond, S.​ (2009) 
  The Journal of Antibiotics, 62(8) pp. 439​-444​.​ DOI: https://doi.org/10.1038/ja.2009.68 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article
  ​ ​Synthesis and Biological Studies of Different Duocarmycin Based Glycosidic Prodrugs for Their Use in the Antibody-Directed Enzyme Prodrug Therapy​
  Tietze, L. F.; Schuster, H. J.; Krewer, B. & Schuberth, I.​ (2009) 
  Journal of Medicinal Chemistry, 52(2) pp. 537​-543​.​ DOI: https://doi.org/10.1021/jm8009102 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Journal Article
  ​ ​ChemInform Abstract: Highly Selective Glycosylated Prodrugs of Cytostatic CC-1065 Analogues for Antibody-Directed Enzyme Tumor Therapy.​
  Tietze, L. F.; Herzig, T.; Fecher Anja, F. A.; Haunert, F. & Schuberth, I.​ (2010) 
  ChemInform, 33(4) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.200204251 
  ​Details  DOI 

• 2010 | Journal Article
  ​ ​ChemInform Abstract: A Comprehensive View on 4-Methyl-2-quinazolinamine, a New Microbial Alkaloid from Streptomyces of TCM Plant Origin.​
  Volmar, D.; Thorn, A.; Schuberth, I. & Grond, S.​ (2010) 
  ChemInform, 41(1) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.201001204 
  ​Details  DOI 

• 2010 | Journal Article
  ​ ​Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity​
  Schuster, H. J.; Krewer, B.; von Hof, J. M.; Schmuck, K.; Schuberth, I.; Alves, F.   & Tietze, L. F.​ (2010) 
  Organic & Biomolecular Chemistry, 8(8) pp. 1833​-1842​.​ DOI: https://doi.org/10.1039/b925070k 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Journal Article
  ​ ​Glycosidic Prodrugs of Highly Potent Bifunctional Duocarmycin Derivatives for Selective Treatment of Cancer​
  Tietze, L. F. ; von Hof, J. M.; Mueller, M.; Krewer, B. & Schuberth, I.​ (2010) 
  Angewandte Chemie International Edition, 49(40) pp. 7336​-7339​.​ DOI: https://doi.org/10.1002/anie.201002502 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article
  ​ ​Synthesis and Biological Evaluation of Prodrugs Based on the Natural Antibiotic Duocarmycin for Use in ADEPT and PMT​
  Tietze, L. F.; Schmuck, K.; Schuster, H. J.; Mueller, M. & Schuberth, I.​ (2011) 
  Chemistry - A European Journal, 17(6) pp. 1922​-1929​.​ DOI: https://doi.org/10.1002/chem.201002798 
  ​Details  DOI  PMID  PMC  WoS 

Researcher

Sort

Items per Page