Author Focke, Niels K.

• 2008 | Journal Article
  ​ ​Voxel-based analysis of whole brain FLAIR at 3T detects focal cortical dysplasia​
  Focke, N. K.; Symms, M. R.; Burdett, J. L. & Duncan, J. S.​ (2008) 
  Epilepsia, 49(5) pp. 786​-793​.​ DOI: https://doi.org/10.1111/j.1528-1167.2007.01474.x 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article
  ​ ​Voxel-based diffusion tensor imaging in patients with mesial temporal lobe epilepsy and hippocampal sclerosis​
  Focke, N. K.; Yogarajah, M.; Bonelli, S. B.; Bartlett, P. A.; Symms, M. R. & Duncan, J. S.​ (2008) 
  NeuroImage, 40(2) pp. 728​-737​.​ DOI: https://doi.org/10.1016/j.neuroimage.2007.12.031 
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• 2008 | Journal Article
  ​ ​Correlation of cognitive functions with voxel-based morphometry in patients with hippocampal sclerosis​
  Focke, N. K.; Thompson, P. J. & Duncan, J. S.​ (2008) 
  Epilepsy & Behavior, 12(3) pp. 472​-476​.​ DOI: https://doi.org/10.1016/j.yebeh.2007.12.011 
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• 2009 | Conference Abstract
  ​ ​FEASIBILITY OF A NOVEL, QUANTITATIVE MAGNETIZATION TRANSFER MAPPING TECHNIQUE IN FOCAL EPILEPSY​
  Focke, N. K.; Klinker, F.; Nitsche, M.; Dechent, P.; Paulus, W. J. & Helms, G.​ (2009)
  Epilepsia, 50 ​8th European Congress on Epileptology​, Berlin, GERMANY.
  Malden​: Wiley-blackwell Publishing, Inc.
  ​Details  WoS 

• 2009 | Conference Abstract
  ​ ​TRACTOGRAPHY AND THE DISTRIBUTED NETWORK DAMAGE UNDERLYING MEMORY IMPAIRMENT IN TEMPORAL LOBE EPILEPSY​
  Yogarajah, M.; Focke, N. K.; Bonelli, S. B.; Parker, G.; Alexander, D. C.; Thompson, P. & Symms, M. et al.​ (2009)
  Epilepsia, 50 ​28th International Epilespy Congress​, Budapest, HUNGARY.
  Malden​: Wiley-blackwell Publishing, Inc.
  ​Details  WoS 

• 2009 | Journal Article | 
  ​ ​Cortical Neuronal Loss and Hippocampal Sclerosis are not Detected by Voxel-Based Morphometry in Individual Epilepsy Surgery Patients​
  Eriksson, S. H.; Thom, M.; Symms, M. R.; Focke, N. K.; Martinian, L.; Sisodiya, S. M. & Duncan, J. S.​ (2009) 
  Human Brain Mapping, 30(10) pp. 3351​-3360​.​ DOI: https://doi.org/10.1002/hbm.20757 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Conference Abstract
  ​ ​STRUCTURAL PLASTICITY OF WHITE MATTER NETWORKS FOLLOWING ANTERIOR TEMPORAL LOBE RESECTION​
  Yogarajah, M.; McEvoy, A. W.; Focke, N. K.; Duncan, J. S.; Koepp, M.; Symms, M. & Bonelli, S. B. et al.​ (2010)
  Journal of Neurology Neurosurgery & Psychiatry, 81(11) ​Annual Meeting of the Association-of-British-Neurologists​, Bournemouth, ENGLAND.
  London​: B M J Publishing Group. DOI: https://doi.org/10.1136/jnnp.2010.226340.29 
  ​Details  DOI  WoS 

• 2010 | Journal Article | Letter Note
  ​ ​Idiopathic REM Sleep Behavior Disorder and Parkinson's Disease - Two Sides of One Coin?​
  Focke, N. K. & Trenkwalder, C.​ (2010) 
  Sleep, 33(6) pp. 731​-732​.​ DOI: https://doi.org/10.1093/sleep/33.6.731 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Journal Article | 
  ​ ​The structural plasticity of white matter networks following anterior temporal lobe resection​
  Yogarajah, M.; Focke, N. K.; Bonelli, S. B.; Thompson, P. J.; Vollmar, C.; McEvoy, A. W. & Alexander, D. C. et al.​ (2010) 
  Brain, 133 pp. 2348​-2364​.​ DOI: https://doi.org/10.1093/brain/awq175 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Conference Abstract
  ​ ​IMAGE BIAS CORRECTION PROFOUNDLY INFLUENCES VOXEL-BASED MORPHOMETRY IN MESIAL TEMPORAL LOBE EPILEPSY​
  Focke, N. K.; Helms, G.; Nitsche, M. A. & Paulus, W. J.​ (2011)
  Epilepsia, 52 pp. 170​-171. ​29th International Epilepsy Congress​, Rome, ITALY.
  Malden​: Wiley-blackwell.
  ​Details  WoS 

• 2011 | Conference Abstract
  ​ ​Effects of the bipolar disorder susceptibility gene CACNA1C on regional grey matter volumes: a voxel-based morphometry (VBM) study​
  Trost, S.; Falkai, P. G.; Wobrock, T.; Scherk, H.; Focke, N. K.; Zilles, D. & Schmitt, A. et al.​ (2011)
  Bipolar Disorders, 13 pp. 101​-102. ​9th International Conference on Bipolar Disorder​, Pittsburgh, PA.
  Malden​: Wiley-blackwell.
  ​Details  WoS 

• 2011 | Journal Article | 
  ​ ​Hippocampal activation correlates with visual confrontation naming: fMRI findings in controls and patients with temporal lobe epilepsy​
  Bonelli, S. B.; Powell, R.; Thompson, P. J.; Yogarajah, M.; Focke, N. K.; Stretton, J. & Vollmar, C. et al.​ (2011) 
  Epilepsy Research, 95(3) pp. 246​-254​.​ DOI: https://doi.org/10.1016/j.eplepsyres.2011.04.007 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article
  ​ ​Individual Voxel-Based Subtype Prediction can Differentiate Progressive Supranuclear Palsy from Idiopathic Parkinson Syndrome and Healthy Controls​
  Focke, N. K.; Helms, G.; Scheewe, S.; Pantel, P. M.; Bachmann, C. G.; Dechent, P. & Ebentheuer, J. et al.​ (2011) 
  Human Brain Mapping, 32(11) pp. 1905​-1915​.​ DOI: https://doi.org/10.1002/hbm.21161 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article
  ​ ​Multi-site voxel-based morphometry - Not quite there yet​
  Focke, N. K.; Helms, G.; Kaspar, S.; Diederich, C.; Toth, V.; Dechent, P. & Mohr, A. et al.​ (2011) 
  NeuroImage, 56(3) pp. 1164​-1170​.​ DOI: https://doi.org/10.1016/j.neuroimage.2011.02.029 
  ​Details  DOI  PMID  PMC  WoS 

• 2011 | Journal Article
  ​ ​Differentiation of Typical and Atypical Parkinson Syndromes by Quantitative MR Imaging​
  Focke, N. K.; Helms, G.; Panthel, K.; Scheewe, S.; Knauth, M.; Bachmann, C. G. & Ebentheuer, J. et al.​ (2011) 
  American Journal of Neuroradiology, 32(11) pp. 2087​-2092​.​ DOI: https://doi.org/10.3174/ajnr.A2865 
  ​Details  DOI  PMID  PMC  WoS 

• 2012 | Conference Paper
  ​ ​Enabling Parallel Computing of a Brain Connectivity Map Using the MediGRID-Infrastructure and FSL​
  Gruetz, R.; Loehnhardt, B.; Focke, N. K.; Viezens, F.; Hoheisel, A.; Dickmann, F. & Krefting, D. ​ (2012)
  ​Proceedings pp. 596​-602. ​20th Euromicro International Conference on Parallel, Distributed and Network-based Processing​, Munich, Germany. DOI: https://doi.org/10.1109/PDP.2012.33 
  ​Details  DOI 

• 2012 | Journal Article
  ​ ​Correlating 3T MRI and histopathology in patients undergoing epilepsy surgery​
  Lockwood-Estrin, G.; Thom, M.; Focke, N. K.; Symms, M. R.; Martinian, L.; Sisodiya, S. M. & Duncan, J. S. et al.​ (2012) 
  Journal of Neuroscience Methods, 205(1) pp. 182​-189​.​ DOI: https://doi.org/10.1016/j.jneumeth.2011.12.014 
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• 2012 | Journal Article
  ​ ​Automated MR image classification in temporal lobe epilepsy​
  Focke, N. K.; Yogarajah, M.; Symms, M. R.; Gruber, O.; Paulus, W. J. & Duncan, J. S.​ (2012) 
  NeuroImage, 59(1) pp. 356​-362​.​ DOI: https://doi.org/10.1016/j.neuroimage.2011.07.068 
  ​Details  DOI  PMID  PMC  WoS 

• 2013 | Journal Article
  ​ ​Distributed, Limbic Gray Matter Atrophy in Patients after Bacterial Meningitis​
  Focke, N. K.; Kallenberg, K.; Mohr, A.; Djukic, M.; Nau, R. & Schmidt, H.​ (2013) 
  American Journal of Neuroradiology, 34(6) pp. 1164​-1167​.​ DOI: https://doi.org/10.3174/ajnr.A3351 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article | 
  ​ ​Do manual and voxel-based morphometry measure the same? A proof of concept study​
  Focke, N. K.; Trost, S.; Paulus, W. J.; Falkai, P. & Gruber, O.​ (2014) 
  Frontiers in Psychiatry, 5 art. 39​.​ DOI: https://doi.org/10.3389/fpsyt.2014.00039 
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• 2014 | Journal Article
  ​ ​Safety of 5 kHz tACS​
  Chaieb, L.; Antal, A.; Pisoni, A.; Saiote, C.; Opitz, A.; Ambrus, G. G. & Focke, N. K. et al.​ (2014) 
  Brain Stimulation, 7(1) pp. 92​-96​.​ DOI: https://doi.org/10.1016/j.brs.2013.08.004 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article
  ​ ​Idiopathic-generalized epilepsy shows profound white matter diffusiontensor imaging alterations​
  Focke, N. K.; Diederich, C.; Helms, G.; Nitsche, M. A.; Lerche, H. & Paulus, W. J.​ (2014) 
  Human Brain Mapping, 35(7) pp. 3332​-3342​.​ DOI: https://doi.org/10.1002/hbm.22405 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article | 
  ​ ​Reproducibility of the Structural Brain Connectome Derived from Diffusion Tensor Imaging​
  Bonilha, L.; Gleichgerrcht, E.; Fridriksson, J.; Rorden, C.; Breedlove, J. L.; Nesland, T. & Paulus, W. J. et al.​ (2015) 
  PLoS ONE, 10(9) art. e0135247​.​ DOI: https://doi.org/10.1371/journal.pone.0135247 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article | 
  ​ ​Voxel-based magnetic resonance image postprocessing in epilepsy​
  Martin, P.; Winston, G. P.; Bartlett, P.; de Tisi, J.; Duncan, J. S. & Focke, N. K.​ (2017) 
  Epilepsia, 58(9) pp. 1653​-1664​.​ DOI: https://doi.org/10.1111/epi.13851 
  ​Details  DOI 

• 2019 | Journal Article | 
  ​ ​MP2RAGE multispectral voxel‐based morphometry in focal epilepsy​
  Kotikalapudi, R.; Martin, P.; Erb, M.; Scheffler, K.; Marquetand, J.; Bender, B. & Focke, N. K.​ (2019) 
  Human Brain Mapping, 40(17) pp. 5042​-5055​.​ DOI: https://doi.org/10.1002/hbm.24756 
  ​Details  DOI  PMID  PMC 

• 2020 | Journal Article | Research Paper
  ​ ​White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study​
  Hatton, S. N.; Huynh, K. H.; Bonilha, L.; Abela, E.; Alhusaini, S.; Altmann, A. & Alvim, M. K. M. et al.​ (2020) 
  Brain: A Journal of Neurology, 143(8) pp. 2454​-2473​.​ DOI: https://doi.org/10.1093/brain/awaa200 
  ​Details  DOI  PMID  PMC 

• 2021 | Journal Article
  ​ ​Heritability of Magnetoencephalography Phenotypes Among Patients With Genetic Generalized Epilepsy and Their Siblings​
  Stier, C.; Elshahabi, A.; Hegner, Y. L.; Kotikalapudi, R.; Marquetand, J.; Braun, C. & Lerche, H. et al.​ (2021) 
  Neurology, pp. 10.1212/WNL.0000000000012144​.​ DOI: https://doi.org/10.1212/WNL.0000000000012144 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Fully automated quality control of rigid and affine registrations of T1w and T2w MRI in big data using machine learning​
  Tummala, S.; Thadikemalla, V. S. G.; Kreilkamp, B. A.; Dam, E. B. & Focke, N. K.​ (2021) 
  Computers in Biology and Medicine, 139 art. S0010482521007915​.​ DOI: https://doi.org/10.1016/j.compbiomed.2021.104997 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​A novel likely pathogenic heterozygous HECW2 missense variant in a family with variable expressivity of neurodevelopmental delay, hypotonia, and epileptiform EEG patterns​
  Heide, E.; Puk, O.; Biskup, S.; Krahn, A.; Rauf, E.; Kreilkamp, B. A. K. & Paulus, W. et al.​ (2021) 
  American Journal of Medical Genetics Part A, 185(12) art. ajmg.a.62427​.​ DOI: https://doi.org/10.1002/ajmg.a.62427 
  ​Details  DOI 

• 2021 | Conference Paper
  ​ ​Machine Learning Framework For Fully Automatic Quality Checking Of Rigid And Affine Registrations In Big Data Brain MRI​
  Tummala, S. & Focke, N. K.​ (2021)
  pp. 1734​-1737. ​2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI)​, Nice, France.
  IEEE. DOI: https://doi.org/10.1109/ISBI48211.2021.9433875 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Directionality of the injected current targeting the P20/N20 source determines the efficacy of 140 Hz transcranial alternating current stimulation (tACS)-induced aftereffects in the somatosensory cortex​
  Mohd Zulkifly, M. F.; Lehr, A.; van de Velden, D.; Khan, A.; Focke, N. K.; Wolters, C. H. & Paulus, W.​ (2022) 
  PLoS One, 17(3) art. e0266107​.​ DOI: https://doi.org/10.1371/journal.pone.0266107 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Combined electrophysiological and morphological phenotypes in patients with genetic generalized epilepsy and their healthy siblings​
  Stier, C.; Loose, M.; Kotikalapudi, R.; Elshahabi, A.; Li Hegner, Y.; Marquetand, J. & Braun, C. et al.​ (2022) 
  Epilepsia, 63(7) pp. 1643​-1657​.​ DOI: https://doi.org/10.1111/epi.17258 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Comparison of Resting-State EEG Network Analyses With and Without Parallel MRI in Genetic Generalized Epilepsy​
  van de Velden, D.; Stier, C.; Kotikalapudi, R.; Heide, E.-C.; Garnica-Agudelo, D. & Focke, N. K.​ (2023) 
  Brain Topography,.​ DOI: https://doi.org/10.1007/s10548-023-00977-6 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Multi-spectral diffusion MRI mega-analysis in genetic generalized epilepsy: Relation to outcomes​
  Kreilkamp, B. A.; Stier, C.; Rauf, E. H.; Martin, P.; Ethofer, S.; Lerche, H. & Kotikalapudi, R. et al.​ (2023) 
  NeuroImage: Clinical, 39 pp. 103474​.​ DOI: https://doi.org/10.1016/j.nicl.2023.103474 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Effects of inverse methods and spike phases on interictal high-density EEG source reconstruction​
  van de Velden, D.; Heide, E.-C.; Bouter, C.; Bucerius, J.; Riedel, C. H. & Focke, N. K.​ (2023) 
  Clinical Neurophysiology, 156 pp. 4​-13​.​ DOI: https://doi.org/10.1016/j.clinph.2023.08.020 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Feasibility of high‐density electric source imaging in the presurgical workflow: effect of number of spikes and automated spike detection​
  Heide, E.; van de Velden, D.; Garnica, D.; Hewitt, M.; Riedel, C. & Focke, N. K.​ (2023) 
  Epilepsia Open, art. epi4.12732​.​ DOI: https://doi.org/10.1002/epi4.12732 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Big Field of View MRI T1w and FLAIR Template - NMRI225​
  Kreilkamp, B. A. K.; Martin, P.; Bender, B.; la Fougère, C.; van de Velden, D.; Stier, C. & Ethofer, S. et al.​ (2023) 
  Scientific Data, 10(1).​ DOI: https://doi.org/10.1038/s41597-023-02087-1 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​A 3D Sparse Autoencoder for Fully Automated Quality Control of Affine Registrations in Big Data Brain MRI Studies​
  Thadikemalla, V. S. G.; Focke, N. K. & Tummala, S.​ (2024) 
  Journal of imaging informatics in medicine,.​ DOI: https://doi.org/10.1007/s10278-023-00933-7 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Neurostimulation targeting the epileptic focus: Current understanding and perspectives for treatment​
  Schulze-Bonhage, A.; Nitsche, M. A.; Rotter, S.; Focke, N. K. & Rao, V. R.​ (2024) 
  Seizure, 117 pp. 183​-192​.​ DOI: https://doi.org/10.1016/j.seizure.2024.03.001 
  ​Details  DOI 

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