Author Klapper, Wolfram

1 to 50 of 68 Items

2006 | Journal Article
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F. E. & Bernd, H. W. et al. (2006)
New England Journal of Medicine, 354(23) pp. 2419-2430. DOI: https://doi.org/10.1056/NEJMoa055351
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2008 | Conference Abstract
Expression of intracellular ABC transporter A3 in aggressive non-Hodgkin lymphoma
Chapuy, B. ; Corsham, S.; Klapper, W.; Ziepert, M.; Truemper, L. H. & Wulf, G. (2008)
Annals of Oncology, 19 pp. 199-200. 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
Conserved oncogenic module activation patterns (COMAPS) identify biologically homogeneous groups of diffuse large B-cell lymphomas and clearly define Burkitt lymphoma
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
Different subtypes of aggressive B cell lymphomas share an epigenetic signature enriched for polycomb targets in stem cells
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Klapper, W.; Wickham-Garcia, E. & Rosolowski, M. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Journal Article
Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
Klapper, W.; Stoecklein, H.; Zeynalova, S.; Ott, G.; Kosari, F.; Rosenwald, A. & Loeffler, M. et al. (2008)
Leukemia, 22(12) pp. 2226-2229. DOI: https://doi.org/10.1038/leu.2008.230
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2008 | Journal Article
Pathway activation patterns in diffuse large B-cell lymphomas
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Leukemia, 22(9) pp. 1746-1754. DOI: https://doi.org/10.1038/leu.2008.166
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2008 | Journal Article
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials
Klapper, W.; Szczepanowski, M.; Burkhardt, B.; Berger, H.; Rosolowski, M.; Bentink, S. & Schwaenen, C. et al. (2008)
Blood, 112(4) pp. 1374-1381. DOI: https://doi.org/10.1182/blood-2008-01-136465
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2008 | Journal Article | Research Paper |
Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration
Chapuy, B. ; Koch, R.; Radunski, U.; Corsham, S.; Cheong, N.; Inagaki, N. & Ban, N. et al. (2008)
Leukemia, 22(8) pp. 1576-1586. DOI: https://doi.org/10.1038/leu.2008.103
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2008 | Review
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma
Hoster, E.; Dreyling, M. H.; Klapper, W.; Gisselbrecht, C.; van Hoof, A.; Kluin-Nelemans, H. C.& Pfreundschuh, M. et al. (2008)
Blood, 111(2) pp. 558-565.
Amer Soc Hematology. DOI: https://doi.org/10.1182/blood-2007-06-095331
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2008 | Journal Article
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
Dierlamm, J.; Penas, E. M. M.; Bentink, S.; Wessendorf, S.; Berger, H.; Hummel, M. & Klapper, W. et al. (2008)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 93(5) pp. 688-696. DOI: https://doi.org/10.3324/haematol.12057
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2009 | Journal Article |
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms.
Martin-Subero, J. I.; Ammerpohl, O.; Bibikova, M.; Wickham-Garcia, E.; Agirre, X.; Alvarez, S. & Brüggemann, M. et al. (2009)
PloS one, 4(9) art. e6986. DOI: https://doi.org/10.1371/journal.pone.0006986
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2009 | Journal Article |
Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
Bernd, H.-W.; Ziepert, M.; Thorns, C.; Klapper, W.; Wacker, H.-H.; Hummel, M. & Stein, H. et al. (2009)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 94(11) pp. 1569-1580. DOI: https://doi.org/10.3324/haematol.2009.008862
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2009 | Journal Article
The addition of rituximab to front-line therapy with CHOP (R-CHOP) results in a higher response rate and longer time to treatment failure in patients with lymphoplasmacytic lymphoma: results of a randomized trial of the German Low-Grade Lymphoma Study Group (GLSG)
Buske, C.; Hoster, E.; Dreyling, M.; Eimermacher, H.; Wandt, H.; Metzner, B. & Fuchs, R. et al. (2009)
Leukemia, 23(1) pp. 153-161. DOI: https://doi.org/10.1038/leu.2008.261
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2009 | Journal Article
Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular War Lymphoma Which Associate with Patient Survival and Gene Expression Status
Schwaenen, C.; Viardot, A.; Berger, H.; Barth, T. F. E.; Bentink, S.; Doehner, H. & Enz, M. et al. (2009)
Genes Chromosomes and Cancer, 48(1) pp. 39-54. DOI: https://doi.org/10.1002/gcc.20617
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2009 | Journal Article
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Ammerpohl, O.; Wickham-Garcia, E. & Rosolowski, M. et al. (2009)
Blood, 113(11) pp. 2488-2497. DOI: https://doi.org/10.1182/blood-2008-04-152900
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2010 | Journal Article |
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis
Scholtysik, R.; Kreuz, M.; Klapper, W.; Burkhardt, B.; Feller, A. C.; Hummel, M. & Loeffler, M. et al. (2010)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(12) pp. 2047-2055. DOI: https://doi.org/10.3324/haematol.2010.026831
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2010 | Journal Article
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Ott, G.; Ziepert, M.; Klapper, W.; Horn, H.; Szczepanowski, M.; Bernd, H.-W. & Thorns, C. et al. (2010)
Blood, 116(23) pp. 4916-4925. DOI: https://doi.org/10.1182/blood-2010-03-276766
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2011 | Review
Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma
Deckert, M.; Engert, A.; Brueck, W.; Ferreri, A. J. M.; Finke, J.; Illerhaus, G.& Klapper, W. et al. (2011)
Leukemia, 25(12) pp. 1797-1807.
Nature Publishing Group. DOI: https://doi.org/10.1038/leu.2011.169
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2011 | Journal Article
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
Salaverria, I.; Philipp, C.; Oschlies, I.; Kohler, C. W.; Kreuz, M.; Szczepanowski, M. & Burkhardt, B. et al. (2011)
Blood, 118(1) pp. 139-147. DOI: https://doi.org/10.1182/blood-2011-01-330795
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2012 | Conference Abstract
Sequencing of pediatric Burkitt lymphoma within the ICGC MMML-Seq project
Richter, J.; Schlesner, M.; Leich, E.; Burkhardt, B.; Hoffmann, S.; Szczepanowski, M. & Kreuz, M. et al. (2012)
British Journal of Haematology, 159 4th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkins Lymphoma, New York, NY.
Hoboken: Wiley-blackwell.
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2012 | Journal Article
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
Richter, J.; Schlesner, M.; Hoffmann, S.; Kreuz, M.; Leich, E.; Burkhardt, B. & Rosolowski, M. et al. (2012)
Nature Genetics, 44(12) pp. 1316-1320. DOI: https://doi.org/10.1038/ng.2469
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2012 | Journal Article
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
Klapper, W.; Kreuz, M.; Kohler, C. W.; Burkhardt, B.; Szczepanowski, M.; Salaverria, I. & Hummel, M. et al. (2012)
Blood, 119(8) pp. 1882-1887. DOI: https://doi.org/10.1182/blood-2011-10-388470
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2013 | Journal Article
Differential diagnosis of lymphoid infiltrates in the central nervous system. Experience of the Network Lymphomas and Lymphomatoid Lesions in the Nervous System
Brueck, W.; Brunn, A.; Klapper, W.; Kuhlmann, T.; Metz, I.; Paulus, W. J. & Deckert, M. (2013)
Der Pathologe, 34(3) pp. 186-+. DOI: https://doi.org/10.1007/s00292-013-1742-9
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2013 | Journal Article
High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas
Salaverria, I.; Martin-Guerrero, I.; Burkhardt, B.; Kreuz, M.; Zenz, T.; Oschlies, I. & Arnold, N. et al. (2013)
Genes Chromosomes and Cancer, 52(2) pp. 150-155. DOI: https://doi.org/10.1002/gcc.22014
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2013 | Journal Article
MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma
Horn, H.; Ziepert, M.; Becher, C.; Barth, T. F. E.; Bernd, H.-W.; Feller, A. C. & Klapper, W. et al. (2013)
Blood, 121(12) pp. 2253-2263. DOI: https://doi.org/10.1182/blood-2012-06-435842
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2014 | Conference Abstract
USP9X promotes resistance to spindle poisons in Diffuse Large B Cell Non Hodgkin's Lymphoma by regulating the mitotic cell fate decision
Engel, K.; Kurutz, J.; Rudelius, M.; Altmann, B.; Fernandez-Saiz, V.; Brunner, A. & Targosz, B.-S. et al. (2014)
Oncology Research and Treatment, 37 pp. 69-70.
Basel: Karger.
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2014 | Conference Abstract
COMPARISON OF CONVENTIONAL CYTOGENETIC ANALYSIS AND WHOLE GENOME SEQUENCING IN GERMINAL-CENTER DERIVED B-CELL LYMPHOMAS IN THE FRAMEWORK OF THE ICGC MMML-SEQ PROJECT
Lopez, C.; Sungalee, S.; Bernhardt, S. H. S. H.; Schlesner, M.; Murga Penas, E. M.; Haake, A. & Richter, J. et al. (2014)
Haematologica, 99 pp. 407-408. 19th Congress of the European-Hematology-Association, Milan, ITALY.
Pavia: Ferrata Storti Foundation.
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2014 | Journal Article
A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma
Salaverria, I.; Martin-Guerrero, I.; Wagener, R.; Kreuz, M.; Kohler, C. W.; Richter, J. & Pienkowska-Grela, B. et al. (2014)
Blood, 123(8) pp. 1187-1198. DOI: https://doi.org/10.1182/blood-2013-06-507996
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2014 | Journal Article | Research Paper
Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma
Koch, R.; Demant, M.; Aung, T.; Diering, N.; Cicholas, A.; Chapuy, B. & Wenzel, D. et al. (2014)
Blood, 123(14) pp. 2189-2198. DOI: https://doi.org/10.1182/blood-2013-08-523886
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2014 | Journal Article |
Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma
Aukema, S. M.; Kreuz, M.; Kohler, C. W.; Rosolowski, M.; Hasenclever, D.; Hummel, M. & Kueppers, R. et al. (2014)
Haematologica, 99(4) pp. 726-735. DOI: https://doi.org/10.3324/haematol.2013.091827
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2015 | Conference Abstract
Lymphocyte enhancer binding factor 1 (LEF-1) affects the interaction of Hodgkin lymphoma with endothelial cells
Harenberg, M. ; Linke, F.; Wilting, J.; Szczepanowski, M.; Klapper, W.; Truemper, L. H. & Kube, D. (2015)
Oncology Research and Treatment, 38
Basel: Karger.
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2015 | Conference Abstract
ANALYSIS OF MECHANISMS OF MALIGNANT TRANSFORMATION IN TP53 WILD-TYPE BURKITT'S LYMPHOMA BY INTEGRATION OF MOLECULAR AND FUNCTIONAL GENOMICS DATA
Huellein, J.; Slabicki, M.; Rosolowski, M.; Scholtysik, R.; Jethwa, A.; Lukas, M. & Tomska, K. et al. (2015)
Haematologica, 100 20th Congress of European-Hematology-Association, Vienna, AUSTRIA.
Pavia: Ferrata Storti Foundation.
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2015 | Journal Article
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
Kretzmer, H.; Bernhart, S. H.; Wang, W.; Haake, A.; Weniger, M. A.; Bergmann, A. K. & Betts, M. J. et al. (2015)
Nature Genetics, 47(11) pp. 1316-+. DOI: https://doi.org/10.1038/ng.3413
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2015 | Journal Article
Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis
Scholtysik, R.; Kreuz, M.; Hummel, M.; Rosolowski, M.; Szczepanowski, M.; Klapper, W. & Loeffler, M. et al. (2015)
International Journal of Cancer, 136(5) pp. 1033-1042. DOI: https://doi.org/10.1002/ijc.29072
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2015 | Journal Article
Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma
Horn, H.; Ziepert, M.; Wartenberg, M.; Staiger, A. M.; Barth, T. F. E.; Bernd, H.-W. & Feller, A. C. et al. (2015)
Leukemia, 29(7) pp. 1564-1570. DOI: https://doi.org/10.1038/leu.2015.43
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2015 | Journal Article
MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells
Doose, G.; Haake, A.; Bernhart, S. H.; Lopez, C.; Duggimpudi, S.; Wojciech, F. & Bergmann, A. K. et al. (2015)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(38) pp. E5261-E5270. DOI: https://doi.org/10.1073/pnas.1505753112
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2015 | Journal Article
The PCBP1 gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma
Wagener, R.; Aukema, S. M.; Schlesner, M.; Haake, A.; Burkhardt, B.; Claviez, A. & Drexler, H. G. et al. (2015)
Genes Chromosomes and Cancer, 54(9) pp. 555-564. DOI: https://doi.org/10.1002/gcc.22268
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2016 | Journal Article |
Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data
Schrader, A.; Meyer, K.; Walther, N.; Stolz, A.; Feist, M. ; Hand, E. & von Bonin, F. et al. (2016)
Oncotarget, 7(30) pp. 47061-47081. DOI: https://doi.org/10.18632/oncotarget.9219
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2016 | Journal Article
Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis
Hezaveh, K.; Kloetgen, A.; Bernhart, S. H.; Das Mahapatra, K.; Lenze, D.; Richter, J. & Haake, A. et al. (2016)
Haematologica, 101(11) pp. 1380-1389. DOI: https://doi.org/10.3324/haematol.2016.143891
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2016 | Journal Article | Letter Note
Complementarity determining region-independent recognition of a superantigen by B-cell antigen receptors of mantle cell lymphoma
Fichtner, M.; Spies, E.; Seismann, H.; Riecken, K.; Engels, N.; Gosch, B. & Dierlamm, J. et al. (2016)
Haematologica, 101(9) art. e381. DOI: https://doi.org/10.3324/haematol.2016.141929
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2016 | Journal Article
Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas
Otto, C.; Scholtysik, R.; Schmitz, R.; Kreuz, M.; Becher, C.; Hummel, M. & Rosenwald, A. et al. (2016)
Genes Chromosomes and Cancer, 55(12) pp. 932-943. DOI: https://doi.org/10.1002/gcc.22391
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2016 | Journal Article |
USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma
Engel, K.; Rudelius, M.; Slawska, J.; Jacobs, L.; Abhari, B. A.; Altmann, B. & Kurutz, J. et al. (2016)
EMBO Molecular Medicine, 8(8) pp. 851-862. DOI: https://doi.org/10.15252/emmm.201506047
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2016 | Journal Article
Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL
Koch, K.; Hoster, E.; Ziepert, M.; Unterhalt, M.; Ott, G.; Rosenwald, A. & Hansmann, M. L. et al. (2016)
Annals of Oncology, 27(7) pp. 1323-1329. DOI: https://doi.org/10.1093/annonc/mdw185
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2017 | Journal Article
TP53 mutation and survival in aggressive B cell lymphoma
Zenz, T.; Kreuz, M.; Fuge, M.; Klapper, W.; Horn, H.; Staiger, A. M. & Winter, D. et al. (2017)
International Journal of Cancer, 141(7) pp. 1381-1388. DOI: https://doi.org/10.1002/ijc.v141.7
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2017 | Journal Article
Clinical Impact of the Cell-of-Origin Classification and the MYC / BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group
Staiger, A. M.; Ziepert, M.; Horn, H.; Scott, D. W.; Barth, T. F.; Bernd, H.-W. & Feller, A. C. et al. (2017)
Journal of Clinical Oncology, 35(22) pp. 2515-2526. DOI: https://doi.org/10.1200/JCO.2016.70.3660
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2017 | Journal Article
Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC
Paul, U.; Richter, J.; Stuhlmann-Laiesz, C.; Kreuz, M.; Nagel, I.; Horn, H. & Staiger, A. M. et al. (2017)
Leukemia & Lymphoma, 59(5) pp. 1213-1221. DOI: https://doi.org/10.1080/10428194.2017.1365851
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2017 | Journal Article
Comprehensive Metaboproteomics of Burkitt's and Diffuse Large B-Cell Lymphoma Cell Lines and Primary Tumor Tissues Reveals Distinct Differences in Pyruvate Content and Metabolism
Schwarzfischer, P.; Reinders, J.; Dettmer, K.; Kleo, K.; Dimitrova, L.; Hummel, M. & Feist, M. et al. (2017)
Journal of Proteome Research, 16(3) pp. 1105-+. DOI: https://doi.org/10.1021/acs.jproteome.6b00164
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2017 | Journal Article | Research Paper
Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents
Szczepanowski, M.; Lange, J.; Kohler, C. W.; Masque-Soler, N.; Zimmermann, M.; Aukema, S. M. & Altenbuchinger, M. et al. (2017)
British Journal of Haematology, 179(1) pp. 116-119. DOI: https://doi.org/10.1111/bjh.14812
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2018 | Journal Article
TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma
Jethwa, A.; Słabicki, M.; Hüllein, J.; Jentzsch, M.; Dalal, V.; Rabe, S. & Wagner, L. et al. (2018)
Blood, 131(25) pp. 2789-2802. DOI: https://doi.org/10.1182/blood-2017-09-806679
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2018 | Journal Article
Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2
Horn, H.; Kohler, C.; Witzig, R.; Kreuz, M.; Leich, E.; Klapper, W. & Hummel, M. et al. (2018)
Haematologica, 103(7) pp. 1182-1190. DOI: https://doi.org/10.3324/haematol.2017.181024
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