Author Llorens, Franc
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2013 | Journal Article
PrP mRNA and protein expression in brain and PrPc in CSF in Creutzfeldt-Jakob disease MM1 and VV2
Llorens, F.; Ansoleaga, B.; Garcia-Esparcia, P.; Zafar, S.; Grau-Rivera, O.; Lopez-Gonzalez, I. & Blanco, R. et al. (2013)
Prion, 7(5) pp. 383-393. DOI: https://doi.org/10.4161/pri.26416
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2014 | Conference Abstract
Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease
Llorens, F.; Zafar, S.; Ansoleaga, B.; Shafiq, M. ; Blanco, R.; Carmona, M. & Gelpi, E. et al. (2014)
Prion, 8
Austin: Landes Bioscience.
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2014 | Journal Article |
Subtype and regional-specific neuroinflammation in sporadic Creutzfeldt-Jakob disease
Llorens, F.; Lopez-Gonzalez, I.; Thuene, K.; Carmona, M.; Zafar, S.; Andreoletti, O. & Zerr, I. et al. (2014)
Frontiers in Aging Neuroscience, 6 art. 198. DOI: https://doi.org/10.3389/fnagi.2014.00198
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2015 | Journal Article
Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease
Llorens, F.; Zafar, S. ; Ansoleaga, B.; Shafiq, M.; Blanco, R.; Carmona, M. & Grau-Rivera, O. et al. (2015)
Neuropathology and Applied Neurobiology, 41(5) pp. 631-645. DOI: https://doi.org/10.1111/nan.12175
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2015 | Journal Article
Increased albumin CSF/serum ratio in dementia with Lewy bodies
Llorens, F.; Schmitz, M.; Gloeckner, S. F.; Kaerst, L.; Hermann, P.; Schmidt, C. D. & Varges, D. A. et al. (2015)
Journal of the Neurological Sciences, 358(1-2) pp. 398-403. DOI: https://doi.org/10.1016/j.jns.2015.10.011
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2015 | Journal Article
Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD
Llorens, F.; Kruse, N.; Schmitz, M.; Shafiq, M.; Gomes da Cunha, J. E.; Gotzman, N. & Zafar, S. et al. (2015)
Journal of Neurology, 262(10) pp. 2305-2311. DOI: https://doi.org/10.1007/s00415-015-7837-x
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2015 | Journal Article
Application of capillary immunoelectrophoresis revealed an age- and gender-dependent regulated expression of PrPC in liver
Arora, A. S. ; Zafar, S.; Kollmar, O.; Llorens, F.; Tahir, W.; Vanselow, S. & Kumar, P. et al. (2015)
Electrophoresis, 36(24) pp. 3026-3033. DOI: https://doi.org/10.1002/elps.201500244
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2015 | Journal Article
Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage
Zafar, S.; Schmitz, M.; Younus, N.; Tahir, W.; Shafiq, M.; Llorens, F. & Ferrer, I. et al. (2015)
Journal of Molecular Neuroscience, 56(2) pp. 329-348. DOI: https://doi.org/10.1007/s12031-015-0544-3
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2015 | Journal Article |
Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains.
Carulla, P.; Llorens, F.; Matamoros-Angles, A.; Aguilar-Calvo, P.; Espinosa, J. C.; Gavín, R. & Ferrer, I. et al. (2015)
Scientific reports, 5 art. 11971. DOI: https://doi.org/10.1038/srep11971
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2015 | Journal Article
Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy
Schmitz, M.; Hermann, P.; Oikonomou, P.; Stoeck, K.; Ebert, E.; Poliakova, T. & Schmidt, C. D. et al. (2015)
Neurobiology of Aging, 36(9) pp. 2597-2606. DOI: https://doi.org/10.1016/j.neurobiolaging.2015.05.013
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2016 | Journal Article
Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease
Ansoleaga, B.; Garcia-Esparcia, P.; Llorens, F.; Hernandez-Ortega, K.; Carmona, M.; Antonio del Rio, J. & Zerr, I. et al. (2016)
Journal of Neuropathology & Experimental Neurology, 75(8) pp. 755-769. DOI: https://doi.org/10.1093/jnen/nlw048
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2016 | Conference Abstract
Identification of new molecular alterations in Fatal Familial Insomnia
Ferrer, I.; Llorens, F.; Frau-Mendez, L.; Fernandez-Vega, I.; Thune, K.; Antonio del Rio, J. & Schmizt, M. et al. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Journal Article
Identification of new molecular alterations in Fatal Familial Insomnia (vol 10, pg S83, 2016)
Ferrer, I.; Llorens, F.; Frau-Mendez, L.; Fernandez-Vega, I.; Thüne, K.; Antonio del Rio, J. & Schmitz, M. et al. (2016)
Prion, 10(4). DOI: https://doi.org/10.1093/hmg/ddw108
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2016 | Conference Abstract
Genetic prion diseases
Zerr, I.; Schmitz, M.; Zafar, S. & Llorens, F. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Journal Article
Progress in CSF biomarker discovery in sCJD
Llorens, F.; Schmitz, M. & Zerr, I. (2016)
Oncotarget, 8(4) pp. 5666-5667. DOI: https://doi.org/10.18632/oncotarget.13998
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2016 | Journal Article
Comparative analysis of cerebrospinal fluid biomarkers in the differential diagnosis of neurodegenerative dementia
Llorens, F.; Schmitz, M.; Karch, A.; Cramm, M.; Lange, P.; Gherib, K. & Varges, D. A. et al. (2016)
Alzheimer s & Dementia, 12(5) pp. 577-589. DOI: https://doi.org/10.1016/j.jalz.2015.10.009
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2016 | Journal Article |
Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients
Schmitz, M.; Llorens, F.; Pracht, A.; Thom, T.; Correia, A. ; Zafar, S. & Ferrer, I. et al. (2016)
Aging, 8(11) pp. 2927-2935. DOI: https://doi.org/10.18632/aging.101101
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2016 | Review
CSF biomarkers in neurodegenerative and vascular dementias
Llorens, F.; Schmitz, M.; Ferrer, I.& Zerr, I. (2016)
Progress in Neurobiology, 138 pp. 36-53.
Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/j.pneurobio.2016.03.003
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2016 | Journal Article
Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic
Schmitz, M.; Ebert, E.; Stoeck, K.; Karch, A.; Collins, S. J.; Calero, M. & Sklaviadis, T. et al. (2016)
Molecular Neurobiology, 53(4) pp. 2189-2199. DOI: https://doi.org/10.1007/s12035-015-9167-5
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2016 | Journal Article
Cerebrospinal alpha-synuclein in alpha-synuclein aggregation disorders: tau/alpha-synuclein ratio as potential biomarker for dementia with Lewy bodies
Llorens, F.; Schmitz, M.; Varges, D. A.; Kruse, N.; Gotzmann, N.; Gmitterova, K. & Mollenhauer, B. et al. (2016)
Journal of Neurology, 263(11) pp. 2271-2277. DOI: https://doi.org/10.1007/s00415-016-8259-0
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2016 | Journal Article
Identification of new molecular alterations in fatal familial insomnia
Llorens, F.; Thuene, K.; Schmitz, M.; Ansoleaga, B.; Frau-Mendez, M. A.; Cramm, M. & Tahir, W. et al. (2016)
Human Molecular Genetics, 25(12) pp. 2417-2436. DOI: https://doi.org/10.1093/hmg/ddw108
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2016 | Journal Article
Mitochondrial DNA differentiates Alzheimer's disease from Creutzfeldt-Jakob disease
Podlesniy, P.; Llorens, F.; Golanska, E.; Sikorska, B.; Liberski, P. P.; Zerr, I. & Trullas, R. (2016)
Alzheimer s & Dementia, 12(5) pp. 546-555. DOI: https://doi.org/10.1016/j.jalz.2015.12.011
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2016 | Journal Article |
Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie
Schmitz, M.; Cramm, M.; Llorens, F.; Candelise, N. ; Mueller-Cramm, D.; Varges, D. A. & Schulz-Schaeffer, W. J. et al. (2016)
Scientific Reports, 6 art. 28711. DOI: https://doi.org/10.1038/srep28711
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2017 | Journal Article |
YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias
Llorens, F.; Thüne, K.; Tahir, W.; Kanata, E.; Diaz-Lucena, D.; Xanthopoulos, K. & Kovatsi, E. et al. (2017)
Molecular Neurodegeneration, 12(1) art. 83. DOI: https://doi.org/10.1186/s13024-017-0226-4
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2017 | Journal Article
Cerebrospinal Fluid Biomarker-Based Diagnosis of Sporadic Creutzfeldt-Jakob Disease: A Validation Study for Previously Established Cutoffs
Llorens, F.; Karch, A.; Golanska, E.; Schmitz, M.; Lange, P.; Sikorska, B. & Liberski, P. P. et al. (2017)
Dementia and Geriatric Cognitive Disorders, 43(1-2) pp. 71-80. DOI: https://doi.org/10.1159/000454802
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2017 | Journal Article |
Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms.
Garcia-Esparcia, P.; López-González, I.; Grau-Rivera, O.; García-Garrido, M. F.; Konetti, A.; Llorens, F. & Zafar, S. et al. (2017)
Frontiers in neurology, 8 art. 89. DOI: https://doi.org/10.3389/fneur.2017.00089
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2018 | Journal Article
Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases
Villar-Piqué, A.; Schmitz, M.; Lachmann, I.; Karch, A.; Calero, O.; Stehmann, C. & Sarros, S. et al. (2018)
Molecular Neurobiology, 56(4) pp. 2811-2821. DOI: https://doi.org/10.1007/s12035-018-1251-1
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2018 | Book Chapter
Cerebrospinal fluid in Creutzfeldt–Jakob disease
Zerr, I.; Zafar, S.; Schmitz, M.& Llorens, F. (2018)
In: Cerebrospinal Fluid in Neurologic Disorders pp. 115-124. Elsevier. DOI: https://doi.org/10.1016/B978-0-12-804279-3.00008-3
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2018 | Book Chapter
Amplification and Detection of Minuscule Amounts of Misfolded Prion Protein by Using the Real-Time Quaking-Induced Conversion
Schmitz, M.; Candelise, N.; Llorens, F.& Zerr, I. (2018)
In:Sigurdsson, Einar M.; Calero, Miguel; Gasset, María (Eds.), Methods in Molecular Biology Amyloid Proteins pp. 257-263. New York, NY: Springer New York. DOI: https://doi.org/10.1007/978-1-4939-7816-8_16
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2018 | Journal Article
Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases
Zerr, I.; Schmitz, M.; Karch, A.; Villar‐Piqué, A.; Kanata, E.; Golanska, E. & Díaz‐Lucena, D. et al. (2018)
Alzheimer's & Dementia, 14(6) pp. 751-763. DOI: https://doi.org/10.1016/j.jalz.2017.12.008
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2018 | Journal Article
Cerebrospinal Fluid Prion Disease Biomarkers in Pre-clinical and Clinical Naturally Occurring Scrapie
Llorens, F.; Barrio, T.; Correia, Â.; Villar-Piqué, A.; Thüne, K.; Lange, P. & Badiola, J. J. et al. (2018)
Molecular Neurobiology, 55(11) pp. 8586-8591. DOI: https://doi.org/10.1007/s12035-018-1014-z
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2018 | Journal Article
CSF nonphosphorylated Tau as a biomarker for the discrimination of AD from CJD
Ermann, N.; Lewczuk, P.; Schmitz, M.; Lange, P.; Knipper, T.; Goebel, S. & Kornhuber, J. et al. (2018)
Annals of Clinical and Translational Neurology, 5(7) pp. 883-887. DOI: https://doi.org/10.1002/acn3.584
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2018 | Journal Article
Variably protease‐sensitive prionopathy presenting within ALS/FTD spectrum
Vicente‐Pascual, M.; Rossi, M.; Gámez, J.; Lladó, A.; Valls, J.; Grau‐Rivera, O. & Ávila Polo, R. et al. (2018)
Annals of Clinical and Translational Neurology, 5(10) pp. 1297-1302. DOI: https://doi.org/10.1002/acn3.632
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2018 | Journal Article |
MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives
Kanata, E.; Thüne, K.; Xanthopoulos, K.; Ferrer, I.; Dafou, D.; Zerr, I. & Sklaviadis, T. et al. (2018)
Frontiers in Aging Neuroscience, 10 art. 220. DOI: https://doi.org/10.3389/fnagi.2018.00220
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2018 | Journal Article |
Interlaboratory validation of cerebrospinal fluid α-synuclein quantification in the diagnosis of sporadic Creutzfeldt-Jakob disease
Kruse, N.; Heslegrave, A.; Gupta, V.; Foiani, M.; Villar-Piqué, A.; Schmitz, M. & Lehmann, S. et al. (2018)
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 10 pp. 461-470. DOI: https://doi.org/10.1016/j.dadm.2018.06.005
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2019 | Journal Article
Cerebrospinal fluid neurofilament light in suspected sporadic Creutzfeldt-Jakob disease
Kanata, E.; Golanska, E.; Villar-Piqué, A.; Karsanidou, A.; Dafou, D.; Xanthopoulos, K. & Schmitz, M. et al. (2019)
Journal of Clinical Neuroscience, 60 pp. 124-127. DOI: https://doi.org/10.1016/j.jocn.2018.09.031
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2019 | Journal Article
RNA editing alterations define manifestation of prion diseases
Kanata, E.; Llorens, F.; Dafou, D.; Dimitriadis, A.; Thüne, K.; Xanthopoulos, K. & Bekas, N. et al. (2019)
Proceedings of the National Academy of Sciences, 116(39) pp. 19727-19735. DOI: https://doi.org/10.1073/pnas.1803521116
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2019 | Journal Article
Cerebrospinal fluid non-phosphorylated tau in the differential diagnosis of Creutzfeldt–Jakob disease: a comparative prospective study with 14-3-3
Llorens, F.; Villar-Piqué, A.; Hermann, P.; Schmitz, M.; Goebel, S.; Waniek, K. & Lachmann, I. et al. (2019)
Journal of Neurology, 267(2) pp. 543-550. DOI: https://doi.org/10.1007/s00415-019-09610-8
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2019 | Journal Article
CSF neurogranin as a neuronal damage marker in CJD: a comparative study with AD
Blennow, K.; Diaz-Lucena, D.; Zetterberg, H.; Villar-Pique, A.; Karch, A.; Vidal, E. & Hermann, P. et al. (2019)
Journal of Neurology, Neurosurgery & Psychiatry, 90(8) pp. 846-853. DOI: https://doi.org/10.1136/jnnp-2018-320155
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2019 | Journal Article | Research Paper
Seeding variability of different alpha synuclein strains in synucleinopathies
Candelise, N.; Schmitz, M.; Llorens, F.; Villar‐Piqué, A.; Cramm, M.; Thom, T. & Silva Correia, S. M. et al. (2019)
Annals of Neurology, 85(5) pp. 691-703. DOI: https://doi.org/10.1002/ana.25446
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2020 | Journal Article
An Update on Autophagy in Prion Diseases
López-Pérez, Ó.; Badiola, J. J.; Bolea, R.; Ferrer, I.; Llorens, F. & Martín-Burriel, I. (2020)
Frontiers in Bioengineering and Biotechnology, 8 art. 975. DOI: https://doi.org/10.3389/fbioe.2020.00975
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2020 | Journal Article
Cerebrospinal fluid neurogranin as a new player in prion disease diagnosis and prognosis
Villar-Pique, A.; Zerr, I. & Llorens, F. (2020)
Neural Regeneration Research, 15(5) pp. 861. DOI: https://doi.org/10.4103/1673-5374.268901
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2020 | Journal Article
A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid β-amyloid42, total-tau, phospho-tau and α-synuclein in the differential diagnosis of neurodegenerative dementia
Diaz-Lucena, D.; Escaramis, G.; Villar-Piqué, A.; Hermann, P.; Schmitz, M.; Varges, D. & Santana, I. et al. (2020)
Journal of Neurology, 267(9) pp. 2567-2581. DOI: https://doi.org/10.1007/s00415-020-09870-9
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2020 | Journal Article
A prognostic model for overall survival in sporadic Creutzfeldt‐Jakob disease
Llorens, F.; Rübsamen, N.; Hermann, P.; Schmitz, M.; Villar‐Piqué, A.; Goebel, S. & Karch, A. et al. (2020)
Alzheimer's & Dementia, 16(10) pp. 1438-1447. DOI: https://doi.org/10.1002/alz.12133
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2020 | Journal Article |
BAMBI and CHGA in Prion Diseases: Neuropathological Assessment and Potential Role as Disease Biomarkers
López-Pérez, Ó.; Bernal-Martín, M.; Hernaiz, A.; Llorens, F.; Betancor, M.; Otero, A. & Toivonen, J. M. et al. (2020)
Biomolecules, 10(5). DOI: https://doi.org/10.3390/biom10050706
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2021 | Journal Article
Validation of Plasma Neurofilament Light Chain as a Marker for α‐Synucleinopathies
Schmitz, M.; Canaslan, S.; Villar‐Piqué, A.; Gmitterová, K.; Varges, D.; Lingor, P. & Llorens, F. et al. (2021)
Movement Disorders, art. mds.28724. DOI: https://doi.org/10.1002/mds.28724
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2021 | Journal Article | Research Paper |
Detection of Cerebrospinal Fluid Neurofilament Light Chain as a Marker for Alpha-Synucleinopathies
Canaslan, S.; Schmitz, M.; Villar-Piqué, A.; Maass, F.; Gmitterová, K.; Varges, D. & Lingor, P. et al. (2021)
Frontiers in Aging Neuroscience, 13. DOI: https://doi.org/10.3389/fnagi.2021.717930
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2021 | Journal Article |
TREM2 expression in the brain and biological fluids in prion diseases
Diaz-Lucena, D.; Kruse, N.; Thüne, K.; Schmitz, M.; Villar-Piqué, A.; da Cunha, J. E. G. & Hermann, P. et al. (2021)
Acta Neuropathologica, 141(6) pp. 841-859. DOI: https://doi.org/10.1007/s00401-021-02296-1
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2021 | Journal Article
Ecto-GPR37: a potential biomarker for Parkinson’s disease
Morató, X.; Garcia-Esparcia, P.; Argerich, J.; Llorens, F.; Zerr, I.; Paslawski, W. & Borràs, E. et al. (2021)
Translational Neurodegeneration, 10(1). DOI: https://doi.org/10.1186/s40035-021-00232-7
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2021 | Journal Article | Research Paper |
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo
Thom, T.; Schmitz, M.; Fischer, A.; Correia, A.; Correia, S.; Llorens, F. & Pique, A. et al. (2021)
Movement Disorders, 37(1) art. mds.28774. DOI: https://doi.org/10.1002/mds.28774
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