Author Nehlmeier, Inga
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2011 | Journal Article | Research Paper
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al. (2011)
Journal of Virology, 85(24) pp. 13363-13372. DOI: https://doi.org/10.1128/JVI.05300-11
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2012 | Journal Article
The role of the alternative coreceptor GPR15 in SIV tropism for human cells
Kiene, M.; Marzi, A.; Urbanczyk, A.; Bertram, S.; Fisch, T.; Nehlmeier, I. & Gnirß, K. et al. (2012)
Virology, 433(1) pp. 73-84. DOI: https://doi.org/10.1016/j.virol.2012.07.012
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2012 | Journal Article |
Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells
Winkler, M.; Bertram, S.; Gnirß, K.; Nehlmeier, I.; Gawanbacht, A.; Kirchhoff, F. & Ehrhardt, C. et al. (2012)
PLoS ONE, 7(8) art. e43337. DOI: https://doi.org/10.1371/journal.pone.0043337
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2014 | Journal Article
DESC1 and MSPL Activate Influenza A Viruses and Emerging Coronaviruses for Host Cell Entry
Zmora, P.; Blazejewska, P.; Moldenhauer, A.-S.; Welsch, K.; Nehlmeier, I.; Wu, Q. & Schneider, H. et al. (2014)
Journal of Virology, 88(20) pp. 12087-12097. DOI: https://doi.org/10.1128/JVI.01427-14
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2015 | Journal Article
Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase
Gnirß, K.; Zmora, P.; Blazejewska, P.; Winkler, M.; Lins, A.; Nehlmeier, I. & Gärtner, S. et al. (2015)
Journal of Virology, 89(18) pp. 9178-9188. DOI: https://doi.org/10.1128/JVI.00615-15
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2015 | Journal Article |
Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.
Karsten, C. B.; Buettner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A. & Sauermann, U. et al. (2015)
Journal of virology, 89(22) pp. 11727-11733. DOI: https://doi.org/10.1128/JVI.01358-15
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2016 | Journal Article
Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions
Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang, H.; Wang, W. & Pöhlmann, S. et al. (2016)
Angewandte Chemie International Edition, 55(15) pp. 4738-4742. DOI: https://doi.org/10.1002/anie.201600593
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2016 | Journal Article
The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies
Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al. (2016)
Journal of Virology, 90(24) pp. 11075-11086. DOI: https://doi.org/10.1128/JVI.01563-16
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2017 | Journal Article
A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry
Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al. (2017)
Journal of Virology, 91(9) art. e00177-17. DOI: https://doi.org/10.1128/JVI.00177-17
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2017 | Journal Article
Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins
Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S. (2017)
Journal of Virology, 91(2) art. e01488-16. DOI: https://doi.org/10.1128/JVI.01488-16
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2017 | Journal Article | Research Paper |
The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells
Brinkmann, C.; Hoffmann, M.; Lübke, A.; Nehlmeier, I.; Krämer-Kühl, A.; Winkler, M. & Pöhlmann, S. (2017)
PLoS One, 12(12) art. e0189073. DOI: https://doi.org/10.1371/journal.pone.0189073
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2017 | Journal Article |
Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.
Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al. (2017)
PloS one, 12(6) art. e0179177. DOI: https://doi.org/10.1371/journal.pone.0179177
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2017 | Journal Article |
Dissecting Multivalent Lectin–Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots
Guo, Y.; Nehlmeier, I.; Poole, E.; Sakonsinsiri, C.; Hondow, N.; Brown, A. & Li, Q. et al. (2017)
Journal of the American Chemical Society, 139(34) pp. 11833-11844. DOI: https://doi.org/10.1021/jacs.7b05104
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2017 | Journal Article |
Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al. (2017)
PLOS ONE, 12(5) art. e0176597. DOI: https://doi.org/10.1371/journal.pone.0176597
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2019 | Journal Article
Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis
Lambertz, R. L. O.; Gerhauser, I.; Nehlmeier, I.; Leist, S. R.; Kollmus, H.; Pöhlmann, S. & Schughart, K. (2019)
Journal of General Virology, 100(7) pp. 1073-1078. DOI: https://doi.org/10.1099/jgv.0.001274
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2019 | Journal Article
Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways
Laporte, M.; Stevaert, A.; Raeymaekers, V.; Boogaerts, T.; Nehlmeier, I.; Chiu, W. & Benkheil, M. et al. (2019)
Journal of Virology, 94(1). DOI: https://doi.org/10.1128/JVI.01430-19
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2019 | Journal Article
Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells
Hoffmann, M.; Nehlmeier, I.; Brinkmann, C.; Krähling, V.; Behner, L.; Moldenhauer, A.-S. & Krüger, N. et al. (2019)
Journal of Virology, 93(3). DOI: https://doi.org/10.1128/JVI.01821-18
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2019 | Journal Article |
Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins
Plegge, T.; Spiegel, M.; Krüger, N.; Nehlmeier, I.; Winkler, M.; González Hernández, M. & Pöhlmann, S. (2019)
PLOS ONE, 14(4) art. e0214968. DOI: https://doi.org/10.1371/journal.pone.0214968
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2019 | Journal Article |
Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques
Winkler, M. ; Gärtner, S.; Markus, L.; Hoffmann, M.; Nehlmeier, I.; Krawczak, M. & Sauermann, U. et al. (2019)
PLoS One, 14(11) art. e0224082. DOI: https://doi.org/10.1371/journal.pone.0224082
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2020 | Journal Article
Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin–Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly
Budhadev, D.; Poole, E.; Nehlmeier, I.; Liu, Y.; Hooper, J.; Kalverda, E. & Akshath, U. S. et al. (2020)
Journal of the American Chemical Society, 142(42) pp. 18022-18034. DOI: https://doi.org/10.1021/jacs.0c06793
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2020 | Journal Article |
H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice
Lambertz, R. L. O.; Gerhauser, I.; Nehlmeier, I.; Gärtner, S.; Winkler, M. ; Leist, S. R. & Kollmus, H. et al. (2020)
Virology Journal, 17(1). DOI: https://doi.org/10.1186/s12985-020-01323-z
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2021 | Journal Article
SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination
Hoffmann, M.; Hofmann-Winkler, H.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Arora, P. et al. (2021)
Cell Reports, 36(3) art. S2211124721008287. DOI: https://doi.org/10.1016/j.celrep.2021.109415
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2021 | Journal Article
SARS-CoV-2 delta variant neutralisation after heterologous ChAdOx1-S/BNT162b2 vaccination
Behrens, G. M.; Cossmann, A.; Stankov, M. V; Nehlmeier, I.; Kempf, A.; Hoffmann, M. & Pöhlmann, S. (2021)
The Lancet, 398(10305) pp. 1041-1042. DOI: https://doi.org/10.1016/S0140-6736(21)01891-2
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2021 | Journal Article
B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination
Arora, P.; Sidarovich, A.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Moldenhauer, A.-S. et al. (2021)
Cell Reports, 37(2) art. S2211124721012894. DOI: https://doi.org/10.1016/j.celrep.2021.109825
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2021 | Journal Article |
Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance
Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Sidarovich, A.; Winkler, M. S. & Schulz, S. et al. (2021)
Cellular & Molecular Immunology, 18(11) pp. 2557-2559. DOI: https://doi.org/10.1038/s41423-021-00772-y
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2021 | Journal Article |
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency
Arora, P.; Rocha, C.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S. & Lier, M. et al. (2021)
Cellular & Molecular Immunology, 18(12) pp. 2673-2675. DOI: https://doi.org/10.1038/s41423-021-00779-5
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2022 | Journal Article
Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy
Hoffmann, M.; Sidarovich, A.; Arora, P.; Krüger, N.; Nehlmeier, I.; Kempf, A. & Graichen, L. et al. (2022)
mBio,. DOI: https://doi.org/10.1128/mbio.00364-22
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2022 | Journal Article
SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination
Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S.; Lier, M. & Schulz, S. et al. (2022)
Cell Reports, art. S2211124722005186. DOI: https://doi.org/10.1016/j.celrep.2022.110754
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2022 | Journal Article
Augmented neutralisation resistance of emerging omicron subvariants BA.2.12.1, BA.4, and BA.5
Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Cossmann, A.; Stankov, M. V & Jäck, H.-M. et al. (2022)
The Lancet Infectious Diseases, 22(8) pp. 1117-1118. DOI: https://doi.org/10.1016/S1473-3099(22)00422-4
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2022 | Journal Article
Omicron sublineage BQ.1.1 resistance to monoclonal antibodies
Arora, P.; Kempf, A.; Nehlmeier, I.; Schulz, S. R; Jäck, H.-M.; Pöhlmann, S. & Hoffmann, M. (2022)
The Lancet Infectious Diseases,. DOI: https://doi.org/10.1016/S1473-3099(22)00733-2
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2022 | Journal Article
The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic
Hoffmann, M.; Krüger, N.; Schulz, S.; Cossmann, A.; Rocha, C.; Kempf, A. & Nehlmeier, I. et al. (2022)
Cell, 185(3) pp. 447-456.e11. DOI: https://doi.org/10.1016/j.cell.2021.12.032
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2022 | Journal Article
Lung cell entry, cell–cell fusion capacity, and neutralisation sensitivity of omicron sublineage BA.2.75
Arora, P.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Schulz, S. R; Dopfer-Jablonka, A. & Baier, E. et al. (2022)
The Lancet Infectious Diseases,. DOI: https://doi.org/10.1016/S1473-3099(22)00591-6
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2022 | Journal Article |
No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2
Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Winkler, M. S.; Lier, M. & Schulz, S. et al. (2022)
Cellular & Molecular Immunology,. DOI: https://doi.org/10.1038/s41423-021-00811-8
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2022 | Journal Article |
Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2
Arora, P.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Schulz, S.; Cossmann, A. & Dopfer-Jablonka, A. et al. (2022)
Cellular & Molecular Immunology,. DOI: https://doi.org/10.1038/s41423-022-00870-5
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2022 | Journal Article |
Native and activated antithrombin inhibits TMPRSS2 activity and SARS‐CoV‐2 infection
Wettstein, L.; Immenschuh, P.; Weil, T.; Conzelmann, C.; Almeida‐Hernández, Y.; Hoffmann, M. & Kempf, A. et al. (2022)
Journal of Medical Virology, art. jmv.28124. DOI: https://doi.org/10.1002/jmv.28124
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2022 | Journal Article
The effect of cilgavimab and neutralisation by vaccine-induced antibodies in emerging SARS-CoV-2 BA.4 and BA.5 sublineages
Arora, P.; Zhang, L.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Dopfer-Jablonka, A. & Schulz, S. R et al. (2022)
The Lancet Infectious Diseases, 22(12) pp. 1665-1666. DOI: https://doi.org/10.1016/S1473-3099(22)00693-4
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2022 | Journal Article |
Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1
Sidarovich, A.; Krüger, N.; Rocha, C.; Graichen, L.; Kempf, A.; Nehlmeier, I. & Lier, M. et al. (2022)
Viruses, 14(11) art. 2475. DOI: https://doi.org/10.3390/v14112475
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2022 | Journal Article |
The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant
Arora, P.; Zhang, L.; Rocha, C.; Graichen, L.; Nehlmeier, I.; Kempf, A. & Cossmann, A. et al. (2022)
International Journal of Molecular Sciences, 23(22) pp. 14057. DOI: https://doi.org/10.3390/ijms232214057
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2023 | Journal Article
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein
Budhadev, D.; Hooper, J.; Rocha, C.; Nehlmeier, I.; Kempf, A. M.; Hoffmann, M. & Krüger, N. et al. (2023)
JACS Au, 3(6) pp. 1755-1766. DOI: https://doi.org/10.1021/jacsau.3c00163
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2023 | Journal Article
Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation
Hoffmann, M.; Behrens, G. M N; Arora, P.; Kempf, A.; Nehlmeier, I.; Cossmann, A. & Manthey, L. et al. (2023)
The Lancet Infectious Diseases, 23(1) pp. 25-28. DOI: https://doi.org/10.1016/S1473-3099(22)00792-7
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2023 | Journal Article |
Omicron subvariant BA.5 efficiently infects lung cells
Hoffmann, M.; Wong, L. Wong, Lok-Yin Roy; Arora, P.; Zhang, L.; Rocha, C.; Odle, A. & Nehlmeier, I. et al. (2023)
Nature Communications, 14(1). DOI: https://doi.org/10.1038/s41467-023-39147-4
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2023 | Journal Article
Neutralisation sensitivity of SARS-CoV-2 lineages EG.5.1 and XBB.2.3
Zhang, L.; Kempf, A.; Nehlmeier, I.; Cossmann, A.; Dopfer-Jablonka, A.; Stankov, M. V & Schulz, S. R et al. (2023)
The Lancet Infectious Diseases, 23(10) pp. e391-e392. DOI: https://doi.org/10.1016/S1473-3099(23)00547-9
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2023 | Journal Article |
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
Metzdorf, K.; Jacobsen, H.; Greweling-Pils, M. C.; Hoffmann, M.; Lüddecke, T.; Miller, F. & Melcher, L. et al. (2023)
Viruses, 15(2). DOI: https://doi.org/10.3390/v15020271
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2023 | Journal Article |
Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5
Hoffmann, M.; Arora, P.; Nehlmeier, I.; Kempf, A.; Cossmann, A.; Schulz, S. R. & Morillas Ramos, G. et al. (2023)
Cellular & Molecular Immunology, 20(4) pp. 419-422. DOI: https://doi.org/10.1038/s41423-023-00988-0
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2023 | Journal Article |
Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage
Nehlmeier, I.; Kempf, A.; Arora, P.; Cossmann, A.; Dopfer-Jablonka, A.; Stankov, M. V. & Schulz, S. R. et al. (2023)
Cellular & Molecular Immunology, pp. 1-3. DOI: https://doi.org/10.1038/s41423-023-01030-z
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2024 | Journal Article
Immune responses following BNT162b2 XBB.1.5 vaccination in patients on haemodialysis in Germany
Cossmann, A.; Hoffmann, M.; Stankov, M. V; Lürken, K.; Morillas Ramos, G.; Kempf, A. & Nehlmeier, I. et al. (2024)
The Lancet Infectious Diseases,. DOI: https://doi.org/10.1016/S1473-3099(23)00783-1
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2024 | Journal Article
SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency
Zhang, L.; Kempf, A.; Nehlmeier, I.; Cossmann, A.; Richter, A.; Bdeir, N. & Graichen, L. et al. (2024)
Cell, 187(3) pp. 596-608.e17. DOI: https://doi.org/10.1016/j.cell.2023.12.025
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2024 | Journal Article
Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y
Oliveira, B. R.; Nehlmeier, I.; Kempf, A. M.; Venugopalan, V.; Rehders, M.; Ceniza, M. E. & Cavalcanti, P. A. T. et al. (2024)
Biochimie,. DOI: https://doi.org/10.1016/j.biochi.2024.02.006
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