Author Pöhlmann, Stefan

1 to 50 of 107 Items
  • 1999 Journal Article
    ​ ​Co‐receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo​
    Pöhlmann, S.; Stolte, N.; Münch, J.; Ten Haaft, P.; Heeney, J.; Stahl‐Hennig, C. & Kirchhoff, F.​ (1999) 
    The Journal of Infectious Diseases180(5) pp. 1494​-1502​.​ DOI: https://doi.org/10.1086/315097 
    Details  DOI 
  • 2007 Journal Article
    ​ ​A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo​
    Pöhlmann, S.; Münch, J.; Aziz, S.; Reeves, J. D.; Otto, C.; Leslie, G. J. & Hofmann, H. et al.​ (2007) 
    Virology360(2) pp. 275​-285​.​ DOI: https://doi.org/10.1016/j.virol.2006.10.020 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells​
    Kühl, A.; Hoffmann, M.; Müller, M. A.; Munster, V. J.; Gnirß, K.; Kiene, M. & Tsegaye, T. S. et al.​ (2011) 
    The Journal of Infectious Diseases204(suppl_3) pp. S840​-S849​.​ DOI: https://doi.org/10.1093/infdis/jir306 
    Details  DOI 
  • 2011 Journal Article
    ​ ​The Ebola Virus Glycoprotein and HIV-1 Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin​
    Kühl, A.; Banning, C.; Marzi, A.; Votteler, J.; Steffen, I.; Bertram, S. & Glowacka, I. et al.​ (2011) 
    The Journal of Infectious Diseases204(Suppl. 3) pp. S850​-S860​.​ DOI: https://doi.org/10.1093/infdis/jir378 
    Details  DOI 
  • 2011 Journal Article
    ​ ​Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response​
    Glowacka, I.; Bertram, S.; Müller, M. A.; Allen, P.; Soilleux, E.; Pfefferle, S. & Steffen, I. et al.​ (2011) 
    Journal of Virology85(9) pp. 4122​-4134​.​ DOI: https://doi.org/10.1128/JVI.02232-10 
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  • 2011 Journal Article
    ​ ​Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion​
    Simmons, G.; Bertram, S.; Glowacka, I.; Steffen, I.; Chaipan, C.; Agudelo, J. & Lu, K. et al.​ (2011) 
    Virology413(2) pp. 265​-274​.​ DOI: https://doi.org/10.1016/j.virol.2011.02.020 
    Details  DOI 
  • 2011 Journal Article
    ​ ​DC-SIGN: Access Portal for Sweet Viral Killers​
    Hofmann, H. & Pöhlmann, S.​ (2011) 
    Cell Host & Microbe10(1) pp. 5​-7​.​ DOI: https://doi.org/10.1016/j.chom.2011.07.003 
    Details  DOI 
  • 2011 Journal Article | Research Paper
    ​ ​Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease​
    Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al.​ (2011) 
    Journal of Virology85(24) pp. 13363​-13372​.​ DOI: https://doi.org/10.1128/JVI.05300-11 
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  • 2012 Journal Article
    ​ ​Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression​
    Gnirß, K.; Kühl, A.; Karsten, C.; Glowacka, I.; Bertram, S.; Kaup, F. & Hofmann, H. et al.​ (2012) 
    Virology424(1) pp. 3​-10​.​ DOI: https://doi.org/10.1016/j.virol.2011.11.031 
    Details  DOI 
  • 2012 Journal Article | 
    ​ ​Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts​
    Bertram, S.; Heurich, A.; Lavender, H.; Gierer, S.; Danisch, S.; Perin, P. & Lucas, J. M. et al.​ (2012) 
    PLoS ONE7(4) art. e35876​.​ DOI: https://doi.org/10.1371/journal.pone.0035876 
    Details  DOI 
  • 2012 Journal Article | 
    ​ ​Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells​
    Winkler, M.; Bertram, S.; Gnirß, K.; Nehlmeier, I.; Gawanbacht, A.; Kirchhoff, F. & Ehrhardt, C. et al.​ (2012) 
    PLoS ONE7(8) art. e43337​.​ DOI: https://doi.org/10.1371/journal.pone.0043337 
    Details  DOI 
  • 2012 Journal Article | 
    ​ ​Host Cell Factors in Filovirus Entry: Novel Players, New Insights​
    Hofmann-Winkler, H.; Kaup, F. & Pöhlmann, S.​ (2012) 
    Viruses4(12) pp. 3336​-3362​.​ DOI: https://doi.org/10.3390/v4123336 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN as a Receptor for pH-Dependent Entry into Human and Animal Cell Lines​
    Hofmann, H.; Li, X.; Zhang, X.; Liu, W.; Kühl, A.; Kaup, F. & Soldan, S. S. et al.​ (2013) 
    Journal of Virology87(8) pp. 4384​-4394​.​ DOI: https://doi.org/10.1128/JVI.02628-12 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia​
    Gierer, S.; Hofmann-Winkler, H.; Albuali, W. H.; Bertram, S.; Al-Rubaish, A. M.; Yousef, A. A. & Al-Nafaie, A. N. et al.​ (2013) 
    Emerging Infectious Diseases19(12) pp. 2034​-2036​.​ DOI: https://doi.org/10.3201/eid1912.130701 
    Details  DOI 
  • 2013 Journal Article
    ​ ​Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research​
    Simmons, G.; Zmora, P.; Gierer, S.; Heurich, A. & Pöhlmann, S.​ (2013) 
    Antiviral Research100(3) pp. 605​-614​.​ DOI: https://doi.org/10.1016/j.antiviral.2013.09.028 
    Details  DOI 
  • 2013 Journal Article
    ​ ​The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies​
    Gierer, S.; Bertram, S.; Kaup, F.; Wrensch, F.; Heurich, A.; Krämer-Kühl, A. & Welsch, K. et al.​ (2013) 
    Journal of Virology87(10) pp. 5502​-5511​.​ DOI: https://doi.org/10.1128/JVI.00128-13 
    Details  DOI 
  • 2013 Journal Article
    ​ ​TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium​
    Bertram, S.; Dijkman, R.; Habjan, M.; Heurich, A.; Gierer, S.; Glowacka, I. & Welsch, K. et al.​ (2013) 
    Journal of Virology87(11) pp. 6150​-6160​.​ DOI: https://doi.org/10.1128/JVI.03372-12 
    Details  DOI 
  • 2013 Journal Article | 
    ​ ​Platelet activation suppresses HIV-1 infection of T cells​
    Solomon Tsegaye, T.; Gnirß, K.; Rahe-Meyer, N.; Kiene, M.; Krämer-Kühl, A.; Behrens, G. & Münch, J. et al.​ (2013) 
    Retrovirology10(1) art. 48​.​ DOI: https://doi.org/10.1186/1742-4690-10-48 
    Details  DOI 
  • 2013 Book Chapter
    ​ ​Cellular entry of retroviruses​
    Lindemann, D.; Steffen, I.& Pöhlmann, S.​ (2013)
    In:​Pöhlmann, Stefan; Simmons, Graham​ (Eds.), Viral Entry into Host Cells pp. 128​-149. ​New York: ​Springer. DOI: https://doi.org/10.1007/978-1-4614-7651-1_7 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article
    ​ ​The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry​
    Gehring, G.; Rohrmann, K.; Atenchong, N.; Mittler, E.; Becker, S.; Dahlmann, F. & Pöhlmann, S. et al.​ (2014) 
    Journal of Antimicrobial Chemotherapy69(8) pp. 2123​-2131​.​ DOI: https://doi.org/10.1093/jac/dku091 
    Details  DOI 
  • 2014 Journal Article
    ​ ​Bitter-sweet symphony: glycan–lectin interactions in virus biology​
    Van Breedam, W.; Pöhlmann, S.; Favoreel, H. W.; de Groot, R. J. & Nauwynck, H. J.​ (2014) 
    FEMS Microbiology Reviews38(4) pp. 598​-632​.​ DOI: https://doi.org/10.1111/1574-6976.12052 
    Details  DOI 
  • 2014 Journal Article
    ​ ​DESC1 and MSPL Activate Influenza A Viruses and Emerging Coronaviruses for Host Cell Entry​
    Zmora, P.; Blazejewska, P.; Moldenhauer, A.-S.; Welsch, K.; Nehlmeier, I.; Wu, Q. & Schneider, H. et al.​ (2014) 
    Journal of Virology88(20) pp. 12087​-12097​.​ DOI: https://doi.org/10.1128/JVI.01427-14 
    Details  DOI 
  • 2014 Journal Article | 
    ​ ​IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms​
    Wrensch, F.; Winkler, M. & Pöhlmann, S.​ (2014) 
    Viruses6(9) pp. 3683​-3698​.​ DOI: https://doi.org/10.3390/v6093683 
    Details  DOI 
  • 2014 Journal Article | 
    ​ ​Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism​
    Gnirß, K.; Fiedler, M.; Krämer-Kühl, A.; Bolduan, S.; Mittler, E.; Becker, S. & Schindler, M. et al.​ (2014) 
    Viruses6(4) pp. 1654​-1671​.​ DOI: https://doi.org/10.3390/v6041654 
    Details  DOI 
  • 2014 Journal Article | 
    ​ ​Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4+ T Cells​
    Kiene, M.; Rethi, B.; Jansson, M.; Dillon, S.; Lee, E.; Lantto, R. & Wilson, C. et al.​ (2014) 
    PLoS ONE9(2) art. e88195​.​ DOI: https://doi.org/10.1371/journal.pone.0088195 
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  • 2014 Journal Article | Research Paper
    ​ ​TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein​
    Heurich, A.; Hofmann-Winkler, H.; Gierer, S.; Liepold, T.; Jahn, O.   & Pöhlmann, S.​ (2014) 
    Journal of Virology88(2) pp. 1293​-1307​.​ DOI: https://doi.org/10.1128/JVI.02202-13 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article
    ​ ​Interferon-Induced Transmembrane Protein–Mediated Inhibition of Host Cell Entry of Ebolaviruses​
    Wrensch, F.; Karsten, C. B.; Gnirß, K.; Hoffmann, M.; Lu, K.; Takada, A. & Winkler, M. et al.​ (2015) 
    Journal of Infectious Diseases212(suppl 2) pp. S210​-S218​.​ DOI: https://doi.org/10.1093/infdis/jiv255 
    Details  DOI 
  • 2015 Journal Article
    ​ ​Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976​
    Hofmann-Winkler, H.; Gnirß, K.; Wrensch, F. & Pöhlmann, S.​ (2015) 
    Journal of Infectious Diseases212(Suppl. 2) pp. S172​-S180​.​ DOI: https://doi.org/10.1093/infdis/jiv101 
    Details  DOI 
  • 2015 Journal Article
    ​ ​Protease inhibitors targeting coronavirus and filovirus entry​
    Zhou, Y.; Vedantham, P.; Lu, K.; Agudelo, J.; Carrion, R.; Nunneley, J. W. & Barnard, D. et al.​ (2015) 
    Antiviral Research116 pp. 76​-84​.​ DOI: https://doi.org/10.1016/j.antiviral.2015.01.011 
    Details  DOI 
  • 2015 Journal Article | 
    ​ ​TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.​
    Zmora, P.; Moldenhauer, A.-S.; Hofmann-Winkler, H. & Pöhlmann, S.​ (2015) 
    PloS one10(9) art. e0138380​.​ DOI: https://doi.org/10.1371/journal.pone.0138380 
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  • 2015 Journal Article | 
    ​ ​Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.​
    Karsten, C. B.; Buettner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A. & Sauermann, U. et al.​ (2015) 
    Journal of virology89(22) pp. 11727​-11733​.​ DOI: https://doi.org/10.1128/JVI.01358-15 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article
    ​ ​Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions​
    Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang, H.; Wang, W. & Pöhlmann, S. et al.​ (2016) 
    Angewandte Chemie International Edition55(15) pp. 4738​-4742​.​ DOI: https://doi.org/10.1002/anie.201600593 
    Details  DOI 
  • 2016 Journal Article
    ​ ​The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases​
    Kühn, N.; Bergmann, S.; Kösterke, N.; Lambertz, R. L. O.; Keppner, A.; van den Brand, J. M. A. & Pöhlmann, S. et al.​ (2016) 
    Journal of Virology90(9) pp. 4298​-4307​.​ DOI: https://doi.org/10.1128/JVI.02693-15 
    Details  DOI 
  • 2016 Journal Article
    ​ ​The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies​
    Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al.​ (2016) 
    Journal of Virology90(24) pp. 11075​-11086​.​ DOI: https://doi.org/10.1128/JVI.01563-16 
    Details  DOI 
  • 2016 Journal Article | 
    ​ ​The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release.​
    Spiegel, M.; Plegge, T. & Pöhlmann, S.​ (2016) 
    Viruses8(7).​ DOI: https://doi.org/10.3390/v8070202 
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  • 2016 Journal Article | 
    ​ ​The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.​
    Hoffmann, M.; González Hernández, M.; Berger, E.; Marzi, A. & Pöhlmann, S.​ (2016) 
    PloS one11(2) art. e0149651​.​ DOI: https://doi.org/10.1371/journal.pone.0149651 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article | 
    ​ ​The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.​
    Hoffmann, M.; Krüger, N.; Zmora, P.; Wrensch, F.; Herrler, G. & Pöhlmann, S.​ (2016) 
    PloS one11(3) art. e0152134​.​ DOI: https://doi.org/10.1371/journal.pone.0152134 
    Details  DOI  PMID  PMC 
  • 2016 Journal Article | 
    ​ ​Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide​
    Plegge, T.; Hofmann-Winkler, H.; Spiegel, M. & Pöhlmann, S.​ (2016) 
    PLOS ONE11(11) art. e0166013​.​ DOI: https://doi.org/10.1371/journal.pone.0166013 
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  • 2017 Journal Article
    ​ ​A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry​
    Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al.​ (2017) 
    Journal of Virology91(9) art. e00177-17​.​ DOI: https://doi.org/10.1128/JVI.00177-17 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset​
    Pöhlmann, S.; Suntz, M.; Akimkin, V.; Bleyer, M. & Kaul, A.​ (2017) 
    Journal of Medical Primatology46(5) pp. 256​-259​.​ DOI: https://doi.org/10.1111/jmp.12269 
    Details  DOI 
  • 2017 Journal Article
    ​ ​pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs​
    Gerlach, T.; Hensen, L.; Matrosovich, T.; Bergmann, J.; Winkler, M.; Peteranderl, C. & Klenk, H.-D. et al.​ (2017) 
    Journal of Virology91(11) art. e00246-17​.​ DOI: https://doi.org/10.1128/JVI.00246-17 
    Details  DOI 
  • 2017 Journal Article
    ​ ​Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins​
    Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S.​ (2017) 
    Journal of Virology91(2) art. e01488-16​.​ DOI: https://doi.org/10.1128/JVI.01488-16 
    Details  DOI 
  • 2017 Journal Article | 
    ​ ​Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.​
    Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al.​ (2017) 
    PloS one12(6) art. e0179177​.​ DOI: https://doi.org/10.1371/journal.pone.0179177 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | 
    ​ ​Dissecting Multivalent Lectin–Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots​
    Guo, Y.; Nehlmeier, I.; Poole, E.; Sakonsinsiri, C.; Hondow, N.; Brown, A. & Li, Q. et al.​ (2017) 
    Journal of the American Chemical Society139(34) pp. 11833​-11844​.​ DOI: https://doi.org/10.1021/jacs.7b05104 
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  • 2017 Journal Article | 
    ​ ​Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin​
    Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al.​ (2017) 
    PLOS ONE12(5) art. e0176597​.​ DOI: https://doi.org/10.1371/journal.pone.0176597 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | 
    ​ ​Rhesus macaque IFITM3 gene polymorphisms and SIV infection​
    Winkler, M.; Gärtner, S.; Wrensch, F.; Krawczak, M.; Sauermann, U. & Pöhlmann, S.​ (2017) 
    PLOS ONE12(3) art. e0172847​.​ DOI: https://doi.org/10.1371/journal.pone.0172847 
    Details  DOI  PMID  PMC 
  • 2018 Journal Article
    ​ ​A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism​
    González-Hernández, M.; Hoffmann, M.; Brinkmann, C.; Nehls, J.; Winkler, M.; Schindler, M. & Pöhlmann, S.​ (2018) 
    Journal of Virology92(13) art. e00403-18​.​ DOI: https://doi.org/10.1128/JVI.00403-18 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2​
    Hoffmann, M. & Pöhlmann, S.​ (2018) 
    Cell Host & Microbe23(6) pp. 697​-699​.​ DOI: https://doi.org/10.1016/j.chom.2018.05.019 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Seroprevalence of viral infections in captive rhesus and cynomolgus macaques​
    Kaul, A.; Schönmann, U. & Pöhlmann, S.​ (2019) 
    Primate Biology6(1) pp. 1​-6​.​ DOI: https://doi.org/10.5194/pb-6-1-2019 
    Details  DOI 
  • 2019 Journal Article | 
    ​ ​Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins​
    Braun, E.; Hotter, D.; Koepke, L.; Zech, F.; Groß, R.; Sparrer, K. M. & Müller, J. A. et al.​ (2019) 
    Cell Reports27(7) art. 2104.e10​.​ DOI: https://doi.org/10.1016/j.celrep.2019.04.063 
    Details  DOI  PMID  PMC 

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