Author Pöhlmann, Stefan
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1999 | Journal Article
Co‐receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo
Pöhlmann, S.; Stolte, N.; Münch, J.; Ten Haaft, P.; Heeney, J.; Stahl‐Hennig, C. & Kirchhoff, F. (1999)
The Journal of Infectious Diseases, 180(5) pp. 1494-1502. DOI: https://doi.org/10.1086/315097
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2007 | Journal Article
A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo
Pöhlmann, S.; Münch, J.; Aziz, S.; Reeves, J. D.; Otto, C.; Leslie, G. J. & Hofmann, H. et al. (2007)
Virology, 360(2) pp. 275-285. DOI: https://doi.org/10.1016/j.virol.2006.10.020
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2011 | Journal Article
Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells
Kühl, A.; Hoffmann, M.; Müller, M. A.; Munster, V. J.; Gnirß, K.; Kiene, M. & Tsegaye, T. S. et al. (2011)
The Journal of Infectious Diseases, 204(suppl_3) pp. S840-S849. DOI: https://doi.org/10.1093/infdis/jir306
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2011 | Journal Article
The Ebola Virus Glycoprotein and HIV-1 Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin
Kühl, A.; Banning, C.; Marzi, A.; Votteler, J.; Steffen, I.; Bertram, S. & Glowacka, I. et al. (2011)
The Journal of Infectious Diseases, 204(Suppl. 3) pp. S850-S860. DOI: https://doi.org/10.1093/infdis/jir378
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2011 | Journal Article
Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response
Glowacka, I.; Bertram, S.; Müller, M. A.; Allen, P.; Soilleux, E.; Pfefferle, S. & Steffen, I. et al. (2011)
Journal of Virology, 85(9) pp. 4122-4134. DOI: https://doi.org/10.1128/JVI.02232-10
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2011 | Journal Article
Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion
Simmons, G.; Bertram, S.; Glowacka, I.; Steffen, I.; Chaipan, C.; Agudelo, J. & Lu, K. et al. (2011)
Virology, 413(2) pp. 265-274. DOI: https://doi.org/10.1016/j.virol.2011.02.020
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2011 | Journal Article
DC-SIGN: Access Portal for Sweet Viral Killers
Hofmann, H. & Pöhlmann, S. (2011)
Cell Host & Microbe, 10(1) pp. 5-7. DOI: https://doi.org/10.1016/j.chom.2011.07.003
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2011 | Journal Article | Research Paper
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
Bertram, S.; Glowacka, I.; Müller, M. A.; Lavender, H.; Gnirss, K.; Nehlmeier, I. & Niemeyer, D. et al. (2011)
Journal of Virology, 85(24) pp. 13363-13372. DOI: https://doi.org/10.1128/JVI.05300-11
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2012 | Journal Article
Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression
Gnirß, K.; Kühl, A.; Karsten, C.; Glowacka, I.; Bertram, S.; Kaup, F. & Hofmann, H. et al. (2012)
Virology, 424(1) pp. 3-10. DOI: https://doi.org/10.1016/j.virol.2011.11.031
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2012 | Journal Article |
Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts
Bertram, S.; Heurich, A.; Lavender, H.; Gierer, S.; Danisch, S.; Perin, P. & Lucas, J. M. et al. (2012)
PLoS ONE, 7(4) art. e35876. DOI: https://doi.org/10.1371/journal.pone.0035876
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2012 | Journal Article |
Influenza A Virus Does Not Encode a Tetherin Antagonist with Vpu-Like Activity and Induces IFN-Dependent Tetherin Expression in Infected Cells
Winkler, M.; Bertram, S.; Gnirß, K.; Nehlmeier, I.; Gawanbacht, A.; Kirchhoff, F. & Ehrhardt, C. et al. (2012)
PLoS ONE, 7(8) art. e43337. DOI: https://doi.org/10.1371/journal.pone.0043337
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2012 | Journal Article |
Host Cell Factors in Filovirus Entry: Novel Players, New Insights
Hofmann-Winkler, H.; Kaup, F. & Pöhlmann, S. (2012)
Viruses, 4(12) pp. 3336-3362. DOI: https://doi.org/10.3390/v4123336
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2013 | Journal Article
Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN as a Receptor for pH-Dependent Entry into Human and Animal Cell Lines
Hofmann, H.; Li, X.; Zhang, X.; Liu, W.; Kühl, A.; Kaup, F. & Soldan, S. S. et al. (2013)
Journal of Virology, 87(8) pp. 4384-4394. DOI: https://doi.org/10.1128/JVI.02628-12
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2013 | Journal Article
Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
Gierer, S.; Hofmann-Winkler, H.; Albuali, W. H.; Bertram, S.; Al-Rubaish, A. M.; Yousef, A. A. & Al-Nafaie, A. N. et al. (2013)
Emerging Infectious Diseases, 19(12) pp. 2034-2036. DOI: https://doi.org/10.3201/eid1912.130701
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2013 | Journal Article
Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
Simmons, G.; Zmora, P.; Gierer, S.; Heurich, A. & Pöhlmann, S. (2013)
Antiviral Research, 100(3) pp. 605-614. DOI: https://doi.org/10.1016/j.antiviral.2013.09.028
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2013 | Journal Article
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies
Gierer, S.; Bertram, S.; Kaup, F.; Wrensch, F.; Heurich, A.; Krämer-Kühl, A. & Welsch, K. et al. (2013)
Journal of Virology, 87(10) pp. 5502-5511. DOI: https://doi.org/10.1128/JVI.00128-13
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2013 | Journal Article
TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium
Bertram, S.; Dijkman, R.; Habjan, M.; Heurich, A.; Gierer, S.; Glowacka, I. & Welsch, K. et al. (2013)
Journal of Virology, 87(11) pp. 6150-6160. DOI: https://doi.org/10.1128/JVI.03372-12
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2013 | Journal Article |
Platelet activation suppresses HIV-1 infection of T cells
Solomon Tsegaye, T.; Gnirß, K.; Rahe-Meyer, N.; Kiene, M.; Krämer-Kühl, A.; Behrens, G. & Münch, J. et al. (2013)
Retrovirology, 10(1) art. 48. DOI: https://doi.org/10.1186/1742-4690-10-48
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2013 | Book Chapter
Cellular entry of retroviruses
Lindemann, D.; Steffen, I.& Pöhlmann, S. (2013)
In:Pöhlmann, Stefan; Simmons, Graham (Eds.), Viral Entry into Host Cells pp. 128-149. New York: Springer. DOI: https://doi.org/10.1007/978-1-4614-7651-1_7
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2014 | Journal Article
The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry
Gehring, G.; Rohrmann, K.; Atenchong, N.; Mittler, E.; Becker, S.; Dahlmann, F. & Pöhlmann, S. et al. (2014)
Journal of Antimicrobial Chemotherapy, 69(8) pp. 2123-2131. DOI: https://doi.org/10.1093/jac/dku091
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2014 | Journal Article
Bitter-sweet symphony: glycan–lectin interactions in virus biology
Van Breedam, W.; Pöhlmann, S.; Favoreel, H. W.; de Groot, R. J. & Nauwynck, H. J. (2014)
FEMS Microbiology Reviews, 38(4) pp. 598-632. DOI: https://doi.org/10.1111/1574-6976.12052
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2014 | Journal Article
DESC1 and MSPL Activate Influenza A Viruses and Emerging Coronaviruses for Host Cell Entry
Zmora, P.; Blazejewska, P.; Moldenhauer, A.-S.; Welsch, K.; Nehlmeier, I.; Wu, Q. & Schneider, H. et al. (2014)
Journal of Virology, 88(20) pp. 12087-12097. DOI: https://doi.org/10.1128/JVI.01427-14
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2014 | Journal Article |
IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent Mechanisms
Wrensch, F.; Winkler, M. & Pöhlmann, S. (2014)
Viruses, 6(9) pp. 3683-3698. DOI: https://doi.org/10.3390/v6093683
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2014 | Journal Article |
Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism
Gnirß, K.; Fiedler, M.; Krämer-Kühl, A.; Bolduan, S.; Mittler, E.; Becker, S. & Schindler, M. et al. (2014)
Viruses, 6(4) pp. 1654-1671. DOI: https://doi.org/10.3390/v6041654
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2014 | Journal Article |
Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4+ T Cells
Kiene, M.; Rethi, B.; Jansson, M.; Dillon, S.; Lee, E.; Lantto, R. & Wilson, C. et al. (2014)
PLoS ONE, 9(2) art. e88195. DOI: https://doi.org/10.1371/journal.pone.0088195
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2014 | Journal Article | Research Paper
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein
Heurich, A.; Hofmann-Winkler, H.; Gierer, S.; Liepold, T.; Jahn, O. & Pöhlmann, S. (2014)
Journal of Virology, 88(2) pp. 1293-1307. DOI: https://doi.org/10.1128/JVI.02202-13
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2015 | Journal Article
Interferon-Induced Transmembrane Protein–Mediated Inhibition of Host Cell Entry of Ebolaviruses
Wrensch, F.; Karsten, C. B.; Gnirß, K.; Hoffmann, M.; Lu, K.; Takada, A. & Winkler, M. et al. (2015)
Journal of Infectious Diseases, 212(suppl 2) pp. S210-S218. DOI: https://doi.org/10.1093/infdis/jiv255
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2015 | Journal Article
Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976
Hofmann-Winkler, H.; Gnirß, K.; Wrensch, F. & Pöhlmann, S. (2015)
Journal of Infectious Diseases, 212(Suppl. 2) pp. S172-S180. DOI: https://doi.org/10.1093/infdis/jiv101
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2015 | Journal Article
Protease inhibitors targeting coronavirus and filovirus entry
Zhou, Y.; Vedantham, P.; Lu, K.; Agudelo, J.; Carrion, R.; Nunneley, J. W. & Barnard, D. et al. (2015)
Antiviral Research, 116 pp. 76-84. DOI: https://doi.org/10.1016/j.antiviral.2015.01.011
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2015 | Journal Article |
TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.
Zmora, P.; Moldenhauer, A.-S.; Hofmann-Winkler, H. & Pöhlmann, S. (2015)
PloS one, 10(9) art. e0138380. DOI: https://doi.org/10.1371/journal.pone.0138380
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2015 | Journal Article |
Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.
Karsten, C. B.; Buettner, F. F. R.; Cajic, S.; Nehlmeier, I.; Neumann, B.; Klippert, A. & Sauermann, U. et al. (2015)
Journal of virology, 89(22) pp. 11727-11733. DOI: https://doi.org/10.1128/JVI.01358-15
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2016 | Journal Article
Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions
Guo, Y.; Sakonsinsiri, C.; Nehlmeier, I.; Fascione, M. A.; Zhang, H.; Wang, W. & Pöhlmann, S. et al. (2016)
Angewandte Chemie International Edition, 55(15) pp. 4738-4742. DOI: https://doi.org/10.1002/anie.201600593
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2016 | Journal Article
The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
Kühn, N.; Bergmann, S.; Kösterke, N.; Lambertz, R. L. O.; Keppner, A.; van den Brand, J. M. A. & Pöhlmann, S. et al. (2016)
Journal of Virology, 90(9) pp. 4298-4307. DOI: https://doi.org/10.1128/JVI.02693-15
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2016 | Journal Article
The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies
Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al. (2016)
Journal of Virology, 90(24) pp. 11075-11086. DOI: https://doi.org/10.1128/JVI.01563-16
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2016 | Journal Article |
The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release.
Spiegel, M.; Plegge, T. & Pöhlmann, S. (2016)
Viruses, 8(7). DOI: https://doi.org/10.3390/v8070202
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2016 | Journal Article |
The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.
Hoffmann, M.; González Hernández, M.; Berger, E.; Marzi, A. & Pöhlmann, S. (2016)
PloS one, 11(2) art. e0149651. DOI: https://doi.org/10.1371/journal.pone.0149651
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2016 | Journal Article |
The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.
Hoffmann, M.; Krüger, N.; Zmora, P.; Wrensch, F.; Herrler, G. & Pöhlmann, S. (2016)
PloS one, 11(3) art. e0152134. DOI: https://doi.org/10.1371/journal.pone.0152134
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2016 | Journal Article |
Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide
Plegge, T.; Hofmann-Winkler, H.; Spiegel, M. & Pöhlmann, S. (2016)
PLOS ONE, 11(11) art. e0166013. DOI: https://doi.org/10.1371/journal.pone.0166013
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2017 | Journal Article
A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry
Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al. (2017)
Journal of Virology, 91(9) art. e00177-17. DOI: https://doi.org/10.1128/JVI.00177-17
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2017 | Journal Article
Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset
Pöhlmann, S.; Suntz, M.; Akimkin, V.; Bleyer, M. & Kaul, A. (2017)
Journal of Medical Primatology, 46(5) pp. 256-259. DOI: https://doi.org/10.1111/jmp.12269
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2017 | Journal Article
pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs
Gerlach, T.; Hensen, L.; Matrosovich, T.; Bergmann, J.; Winkler, M.; Peteranderl, C. & Klenk, H.-D. et al. (2017)
Journal of Virology, 91(11) art. e00246-17. DOI: https://doi.org/10.1128/JVI.00246-17
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2017 | Journal Article
Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins
Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S. (2017)
Journal of Virology, 91(2) art. e01488-16. DOI: https://doi.org/10.1128/JVI.01488-16
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2017 | Journal Article |
Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.
Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al. (2017)
PloS one, 12(6) art. e0179177. DOI: https://doi.org/10.1371/journal.pone.0179177
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2017 | Journal Article |
Dissecting Multivalent Lectin–Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots
Guo, Y.; Nehlmeier, I.; Poole, E.; Sakonsinsiri, C.; Hondow, N.; Brown, A. & Li, Q. et al. (2017)
Journal of the American Chemical Society, 139(34) pp. 11833-11844. DOI: https://doi.org/10.1021/jacs.7b05104
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2017 | Journal Article |
Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al. (2017)
PLOS ONE, 12(5) art. e0176597. DOI: https://doi.org/10.1371/journal.pone.0176597
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2017 | Journal Article |
Rhesus macaque IFITM3 gene polymorphisms and SIV infection
Winkler, M.; Gärtner, S.; Wrensch, F.; Krawczak, M.; Sauermann, U. & Pöhlmann, S. (2017)
PLOS ONE, 12(3) art. e0172847. DOI: https://doi.org/10.1371/journal.pone.0172847
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2018 | Journal Article
A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism
González-Hernández, M.; Hoffmann, M.; Brinkmann, C.; Nehls, J.; Winkler, M.; Schindler, M. & Pöhlmann, S. (2018)
Journal of Virology, 92(13) art. e00403-18. DOI: https://doi.org/10.1128/JVI.00403-18
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2018 | Journal Article
Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2
Hoffmann, M. & Pöhlmann, S. (2018)
Cell Host & Microbe, 23(6) pp. 697-699. DOI: https://doi.org/10.1016/j.chom.2018.05.019
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2019 | Journal Article
Seroprevalence of viral infections in captive rhesus and cynomolgus macaques
Kaul, A.; Schönmann, U. & Pöhlmann, S. (2019)
Primate Biology, 6(1) pp. 1-6. DOI: https://doi.org/10.5194/pb-6-1-2019
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2019 | Journal Article |
Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins
Braun, E.; Hotter, D.; Koepke, L.; Zech, F.; Groß, R.; Sparrer, K. M. & Müller, J. A. et al. (2019)
Cell Reports, 27(7) art. 2104.e10. DOI: https://doi.org/10.1016/j.celrep.2019.04.063
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