Author Wieland, Eberhard
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2000 | Journal Article
Acute effect of HELP treatment on radical scavenging enzyme activities, total glutathione concentrations in granulocytes, and selenium in plasma
Schettler, V.; Methe, H.; Schuff-Werner, P.; Mueller, G. A. & Wieland, E. (2000)
European Journal of Clinical Investigation, 30(1) pp. 26-32.
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2000 | Journal Article
Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and Emit
Shipkova, M.; Schutz, E.; Armstrong, V. W.; Niedmann, P. D.; Oellerich, M. & Wieland, E. (2000)
Clinical Chemistry, 46(3) pp. 365-372.
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2000 | Conference Paper
c-fos and c-jun mRNA expression in a pig liver model of ischemia/reperfusion: effect of extended cold storage and the antioxidant idebenone
Wieland, E.; Oellerich, M.; Braun, F. & Schutz, E. (2000)
Clinical Biochemistry, 33(4) pp. 285-290. SFRR (Europe) Summer Meeting on Antioxidants, Adaptation and Aging, DRESDEN, GERMANY.
Oxford: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S0009-9120(00)00070-9
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2000 | Journal Article
Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring
Oellerich, M.; Shipkova, M.; Schutz, E.; Wieland, E.; Weber, L. T.; Tonshoff, B. & Armstrong, V. W. (2000)
Therapeutic Drug Monitoring, 22(1) pp. 20-26. DOI: https://doi.org/10.1097/00007691-200002000-00004
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2000 | Journal Article | Letter Note
Evaluation of an immunoassay for mycophenolic acid
Schutz, E.; Shipkova, M.; Wieland, E.; Niedmann, P. D.; Armstrong, V. W. & Oellerich, M. (2000)
Therapeutic Drug Monitoring, 22(1) pp. 141-142. DOI: https://doi.org/10.1097/00007691-200002000-00030
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2000 | Journal Article
Induction of cytokine release by the acyl glucuronide of mycophenolic acid: A link to side effects?
Wieland, E.; Shipkova, M.; Schellhaas, U.; Schütz, E.; Niedmann, P. D.; Armstrong, V. W. & Oellerich, M. (2000)
Clinical Biochemistry, 33(2) pp. 107-113. DOI: https://doi.org/10.1016/S0009-9120(99)00101-0
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2001 | Journal Article | Letter Note
Quantification of mycophenolic acid in plasma samples collected during and immediately after intravenous administration of mycophenolate mofetil
Shipkova, M.; Armstrong, V. W.; Kiehl, M. G.; Niedmann, P. D.; Schutz, E.; Oellerich, M. & Wieland, E. (2001)
Clinical Chemistry, 47(8) pp. 1485-1488.
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2001 | Conference Paper
Preliminary report on the effect of xenoperfusion with human blood on cyclosporin A metabolism and cytochrome-P-4503A4-mRNA expression in a pig liver perfusion model
Wieland, E.; Shipkova, M.; Schütz, E.; Braun, F.; Niedmann, P.-D.; Armstrong, V. W. & Ringe, B. et al. (2001)
Clinical Biochemistry, 34(1) pp. 53-57. Analytical Conference 2000, MUNICH, GERMANY.
Oxford: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S0009-9120(00)00203-4
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2001 | Journal Article
Effect of heparin-induced extracorporeal low-density lipoprotein precipitation (HELP) apheresis on hepatitis C plasma virus load
Schettler, V.; Monazahian, M.; Wieland, E.; Thomssen, R. & Mueller, G. A. (2001)
THERAPEUTIC APHERESIS, 5(5) pp. 384-386. DOI: https://doi.org/10.1046/j.1526-0968.2001.00374.x
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2001 | Journal Article
Reduction of hepatitis C virus load by HELP-LDL apheresis
Schettler, V.; Monazahian, M.; Wieland, E.; Ramadori, G.; Grunewald, R. W.; Thomssen, R. & Mueller, G. A. (2001)
European Journal of Clinical Investigation, 31(2) pp. 154-155. DOI: https://doi.org/10.1046/j.1365-2362.2001.00758.x
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2001 | Journal Article | Letter Note
The HFE gene S65C polymorphism is rare among Bulgarian porphyria cutanea tarda patients
von Ahsen, N.; Wieland, E.; Adjarov, D.; Krastev, Z.; Oellerich, M. & Ivanova, A. (2001)
Journal of Hepatology, 34(3) pp. 484-485. DOI: https://doi.org/10.1016/S0168-8278(00)00019-2
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2001 | Journal Article
Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes
Shipkova, M.; Strassburg, C. P.; Braun, F.; Streit, F.; Grone, H. J.; Armstrong, V. W. & Tukey, R. H. et al. (2001)
British Journal of Pharmacology, 132(5) pp. 1027-1034. DOI: https://doi.org/10.1038/sj.bjp.0703898
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2001 | Journal Article
Enzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins
Stoyanova, E.; Tesch, A.; Armstrong, V. W. & Wieland, E. (2001)
Clinical Biochemistry, 34(6) pp. 483-490. DOI: https://doi.org/10.1016/S0009-9120(01)00258-2
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2001 | Journal Article
Lipid hydroperoxides and free radical scavenging enzyme activities in preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome: No evidence for circulating primary products of lipid peroxidation
Diedrich, F.; Renner, A.; Rath, W.; Kuhn, W. & Wieland, E. (2001)
American Journal of Obstetrics and Gynecology, 185(1) pp. 166-172. DOI: https://doi.org/10.1067/mob.2001.115281
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2001 | Journal Article
Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: Preliminary report
Shipkova, M.; Armstrong, V. W.; Kuypers, D.; Perner, F.; Fabrizi, V.; Holzer, H. & Wieland, E. et al. (2001)
Therapeutic Drug Monitoring, 23(6) pp. 717-721. DOI: https://doi.org/10.1097/00007691-200112000-00020
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2001 | Conference Paper
The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes
Shipkova, M.; Wieland, E.; Schutz, E.; Wiese, C. H.; Niedmann, P. D.; Oellerich, M. & Armstrong, V. W. (2001)
Transplantation Proceedings, 33(1-2) pp. 1080-1081. 18th World Congress of the Transplantation-Society, ROME, ITALY.
New york: Elsevier Science Inc. DOI: https://doi.org/10.1016/S0041-1345(00)02424-6
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2002 | Journal Article
Effect of age and hypoxia/reoxygenation on mRNA expression of antioxidative enzymes in rat liver and kidneys
Martin, R.; Fitzl, G.; Mozet, C.; Martin, H.; Welt, K. & Wieland, E. (2002)
Experimental Gerontology, 37(12) art. PII S0531-5565(02)00168-7. DOI: https://doi.org/10.1016/S0531-5565(02)00168-7
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2002 | Journal Article
Highly effective reduction of C-reactive protein in patients with coronary heart disease by extracorporeal low density lipoprotein apheresis
Wieland, E.; Schettler, V. & Armstrong, V. W. (2002)
Atherosclerosis, 162(1) art. PII S0021-9150(01)00698-0. DOI: https://doi.org/10.1016/S0021-9150(01)00698-0
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2002 | Journal Article
First steps toward the establishment of a German low-density lipoprotein-apheresis registry: Recommendations for the indication and for quality management
Schettler, V.; Wieland, E.; Armstrong, V. W.; Kleinoeder, T.; Grunewald, R. W. & Mueller, G. A. (2002)
THERAPEUTIC APHERESIS, 6(5) pp. 381-383. DOI: https://doi.org/10.1046/j.1526-0968.2002.00426.x
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2002 | Journal Article
Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients
Shipkova, M.; Armstrong, V. W.; Weber, L. T.; Niedmann, P. D.; Wieland, E.; Haley, J. & Tonshoff, B. et al. (2002)
Therapeutic Drug Monitoring, 24(3) pp. 390-399. DOI: https://doi.org/10.1097/00007691-200206000-00011
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2002 | Journal Article
A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis
Maes, B.; Oellerich, M.; Ceuppens, J. L.; Armstrong, V. W.; Evenepoel, P.; Kuypers, D. & Messiaen, T. et al. (2002)
Nephrology Dialysis Transplantation, 17(5) pp. 923-926. DOI: https://doi.org/10.1093/ndt/17.5.923
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2003 | Conference Abstract
Pre-dose plums concentrations of the reactive acyl glucuronide of mycophenolic acid (AcMPAG) in kidney transplant recipients under therapy with mycophenolate mofeto (MMF), tacrolimus and steroids
Shipkova, M.; Maes, B.; Armstrong, V. W.; Wieland, E. & Oellerich, M. (2003)
Therapeutic Drug Monitoring, 25(4) 8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, BASEL, SWITZERLAND.
Philadelphia: Lippincott Williams & Wilkins.
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2003 | Journal Article | Letter Note
Commentary on: Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods - Response
Shipkova, M.; Armstrong, V. W.; Wieland, E. & Oellerich, M. (2003)
Clinical Chemistry, 49(9) pp. 1551-1552.
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2003 | Conference Abstract
Relationship between plasma concentrations of mycophenolic acid (MPA) and its acyl glucuronide (AcMPAG) and intestinal damage in Wistar rats treated with mycophenolate mofetil (MMF)
Shipkova, M.; Voland, A.; Grone, H. J.; Armstrong, V. W.; Oellerich, M. & Wieland, E. (2003)
Therapeutic Drug Monitoring, 25(4) 8th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, BASEL, SWITZERLAND.
Philadelphia: Lippincott Williams & Wilkins.
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2003 | Journal Article
Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods
Shipkova, M.; Armstrong, V. W.; Wieland, E. & Oellerich, M. (2003)
Clinical Chemistry, 49(2) pp. 260-268. DOI: https://doi.org/10.1373/49.2.260
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2003 | Conference Paper
Is there evidence for excessive free radical production in vivo during ultrasound-assisted liposuction?
Herr, J.; Hofheinz, H.; Hertl, C.; Olbrisch, R. R. & Wieland, E. (2003)
Plastic & Reconstructive Surgery, 111(1) pp. 425-429. Symposium of the European-Association-of-Plastic-Surgeons, HELSINKI, FINLAND.
Philadelphia: Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/01.PRS.0000036031.11944.4E
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2003 | Journal Article
No acute impact of lipid apheresis treatment on free radical scavenging enzyme gene expression in white blood cells
Schettler, V.; Krontal, J.; Scheel, A. & Wieland, E. (2003)
European Journal of Clinical Investigation, 33(2) pp. 134-140. DOI: https://doi.org/10.1046/j.1365-2362.2003.01119.x
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2003 | Journal Article
No acute impact of haemodialysis treatment on free radical scavenging enzyme gene expression in white blood cells
Schettler, V.; Kuhn, W.; Kleinoeder, T.; Armstrong, V. W.; Oellerich, M.; Mueller, G. A. & Wieland, E. (2003)
Journal of Internal Medicine, 253(2) pp. 201-207. DOI: https://doi.org/10.1046/j.1365-2796.2003.01088.x
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2003 | Review
Acyl glucuronide drug metabolites: Toxicological and analytical implications
Shipkova, M.; Armstrong, V. W.; Oellerich, M.& Wieland, E. (2003)
Therapeutic Drug Monitoring, 25(1) pp. 1-16.
Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/00007691-200302000-00001
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2004 | Journal Article
cDNA microarray analysis reveals new candidate genes possibly linked to side effects under mycophenolate mofetil therapy
Shipkova, M.; Spielbauer, B.; Voland, A.; Grone, H. J.; Armstrong, V. W.; Oellerich, M. & Wieland, E. (2004)
Transplantation Journal, 78(8) pp. 1145-1152. DOI: https://doi.org/10.1097/01.TP.0000137262.06252.05
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2004 | Conference Paper
Expression of E-selectin and its transcripts during intestinal ischemia-reperfusion injury in pigs
Braun, F.; Hosseini, M.; Wieland, E.; Sattler, B.; Laabs, S.; Lorf, T. & Mueller, A. R. et al. (2004)
Transplantation Proceedings, 36(2) pp. 265-266. 8th International Small Bowel Transplant Symposium, Miami, FL.
New york: Elsevier Science Inc. DOI: https://doi.org/10.1016/j.transproceed.2004.01.081
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2004 | Journal Article
Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue
Shipkova, M.; Beck, H.; Voland, A.; Armstrong, V. W.; Grone, H. J.; Oellerich, M. & Wieland, E. (2004)
PROTEOMICS, 4(9) pp. 2728-2738. DOI: https://doi.org/10.1002/pmic.200300836
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2004 | Conference Paper
Kinetics and localization of interleukin-2, interleukin-6, heat shock protein 70, and interferon gamma during intestinal-rerfusion injury
Braun, F.; Hosseini, M.; Wieland, E.; Sattler, B.; Mueller, A. R.; Fandrich, F. & Kremer, B. et al. (2004)
Transplantation Proceedings, 36(2) pp. 267-269. 8th International Small Bowel Transplant Symposium, Miami, FL.
New york: Elsevier Science Inc. DOI: https://doi.org/10.1016/j.transproceed.2004.01.082
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2004 | Journal Article | Letter Note
Determination of thiopurine methyltransferase activity in isolated human erythrocytes does not reflect putative in vivo enzyme inhibition by sulfasalazine
Shipkova, M.; Niedmann, P. D.; Armstrong, V. W.; Oellerich, M. & Wieland, E. (2004)
Clinical Chemistry, 50(2) pp. 438-441. DOI: https://doi.org/10.1373/clinchem.2003.026096
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2006 | Conference Abstract
Cyclosporin determination with different immunoassays in four laboratories using routine patient samples from different transplant types: Performance of automated immunoassays and comparability to tandem mass spectrometry
Domke, I.; Shipkova, M.; Engelmayer, J.; Kheradmand, M.; Luthe, H.; Pou, L. & Streit, F. et al. (2006)
Clinical Chemistry, 52(6) 58th Annual Meeting of the American-Association-of-Clinical-Chemistry, Chicago, IL.
Washington: Amer Assoc Clinical Chemistry.
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2006 | Conference Abstract
Comparability between automated immunoassays and LC-MS/MS for tacrolimus determination using routine patient samples
Domke, I.; Vukovich, T.; Engelmayer, J.; Kheradmand, M.; Luthe, H.; Shipkova, M. & Streit, F. et al. (2006)
Clinical Chemistry, 52(6) 58th Annual Meeting of the American-Association-of-Clinical-Chemistry, Chicago, IL.
Washington: Amer Assoc Clinical Chemistry.
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2006 | Journal Article
Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a caucasian population
Shipkova, M.; Lorenz, K.; Oellerich, M.; Wieland, E. & von Ahsen, N. (2006)
Clinical Chemistry, 52(2) pp. 240-247. DOI: https://doi.org/10.1373/clinchem.2005.059501
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2006 | Journal Article
Marmoset glutathione peroxidases: cDNA sequences, molecular evolution, and gene expression
Atanasova, S.; von Ahsen, N.; Schlumbohm, C.; Wieland, E.; Oellerich, M. & Armstrong, V. W. (2006)
Journal of Medical Primatology, 35(3) pp. 155-164. DOI: https://doi.org/10.1111/j.1600-0684.2006.00158.x
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2007 | Conference Abstract
The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro
Feichtiger, H.; Wieland, E.; Armstrong, V. W. & Shipkova, M. (2007)
Therapeutic Drug Monitoring, 29(4) pp. 539-540. 10th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Nice, FRANCE.
Philadelphia: Lippincott Williams & Wilkins.
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2007 | Review
Effects of LDL-apheresis - more than reduction of cholesterol?
Schettler, V.& Wieland, E. (2007)
DMW - Deutsche Medizinische Wochenschrift, 132(11) pp. 575-578.
Georg Thieme Verlag Kg. DOI: https://doi.org/10.1055/s-2007-970381
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2007 | Journal Article
Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats
Asif, A. R.; Armstrong, V. W.; Voland, A.; Wieland, E.; Oellerich, M. & Shipkova, M. (2007)
Biochimie, 89(3) pp. 393-402. DOI: https://doi.org/10.1016/j.biochi.2006.09.016
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2007 | Journal Article
Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in Exon 6
Atanasova, S.; Shipkova, M.; Svinarov, D.; Mladenova, A.; Genova, M.; Wieland, E. & Oellerich, M. et al. (2007)
Therapeutic Drug Monitoring, 29(1) pp. 6-10. DOI: https://doi.org/10.1097/FTD.0b013e3180308554
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2009 | Journal Article
Differential Proteomic Analysis of Lymphocytes Treated With Mycophenolic Acid Reveals Caspase 3-Induced Cleavage of Rho GDP Dissociation Inhibitor 2
Heller, T.; Asif, A. R.; Petrova, D. T.; Doncheva, Y.; Wieland, E.; Oellerich, M. & Shipkova, M. et al. (2009)
Therapeutic Drug Monitoring, 31(2) pp. 211-217.
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2009 | Journal Article
Regulation of IL2 and NUCB1 in Mononuclear Cells Treated With Acyl Glucuronide of Mycophenolic Acid Reveals Effects Independent of Inosine Monophosphate Dehydrogenase Inhibition
Petrova, D. T; Heller, T.; Hitt, R.; Wieland, E.; Oellerich, M.; Armstrong, V. W & Shipkova, M. (2009)
Therapeutic Drug Monitoring, 31(1) pp. 31-41. DOI: https://doi.org/10.1097/FTD.0b013e318192693e
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2009 | Journal Article
Prenatal dexamethasone exposure in the common marmoset monkey enhances gene expression of antioxidant enzymes in the aorta of adult offspring
Atanasova, S.; Wieland, E.; Schlumbohm, C.; Korecka, M.; Shaw, L. M.; von Ahsen, N. & Fuchs, E. et al. (2009)
Stress, 12(3) art. PII 905441944. DOI: https://doi.org/10.1080/10253890802305075
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2009 | Journal Article
A Case Report of Darbepoetin Treatment in a Patient With Sickle Cell Disease and Chronic Renal Failure Undergoing Regular Hemodialysis Procedures That Induce a Dose-Dependent Extension of Blood Transfusion Intervals
Schettler, V. & Wieland, E. (2009)
Therapeutic Apheresis and Dialysis, 13(1) pp. 80-82. DOI: https://doi.org/10.1111/j.1744-9987.2009.00602.x
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2010 | Journal Article
Investigation of the Crossreactivity of Mycophenolic Acid Glucuronide Metabolites and of Mycophenolate Mofetil in the Cedia MPA Assay
Shipkova, M.; Schuetz, E.; Besenthal, I.; Fraunberger, P. & Wieland, E. (2010)
Therapeutic Drug Monitoring, 32(1) pp. 79-85.
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2010 | Journal Article
The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro
Feichtiger, H.; Wieland, E.; Armstrong, V. W. & Shipkova, M. (2010)
Clinical Biochemistry, 43(1-2) pp. 208-213. DOI: https://doi.org/10.1016/j.clinbiochem.2009.08.023
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2010 | Review
Biomarkers as a Tool for Management of Immunosuppression in Transplant Patients
Wieland, E.; Olbricht, C. J.; Suesal, C.; Gurragchaa, P.; Boehler, T.; Israeli, M.& Sommerer, C. et al. (2010)
Therapeutic Drug Monitoring, 32(5) pp. 560-572.
Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/FTD.0b013e3181efb3d2
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2011 | Conference Abstract
Comparability and imprecision of eight frequently used commercially available immunoassays for therapeutic drug monitoring
Shipkova, M.; Petrova, D. T.; Rosler, A. E.; Orth, M.; Engelmayer, J.; Wieland, E. & Brandhorst, G. et al. (2011)
Therapeutic Drug Monitoring, 33(4) 12th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Stuttgart, GERMANY.
Philadelphia: Lippincott Williams & Wilkins.
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