Author Agafonov, Dmitry E.
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2016 | Journal Article
ATP gamma S stalls splicing after B complex formation but prior to spliceosome activation
Agafonov, D. E.; van Santen, M.; Kastner, B.; Dube, P.; Will, C. L.; Urlaub, H. & Luehrmann, R. (2016)
RNA, 22(9) pp. 1329-1337. DOI: https://doi.org/10.1261/rna.057810.116
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2016 | Journal Article
Molecular architecture of the human U4/U6.U5 tri-snRNP
Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.-T.; Urlaub, H. & Lührmann, R. et al. (2016)
Science, 351(6280) pp. 1416-1420. DOI: https://doi.org/10.1126/science.aad2085
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2016 | Journal Article | Research Paper |
A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity
Boesler, C.; Rigo, N.; Anokhina, M. M.; Tauchert, M. J. ; Agafonov, D. E.; Kastner, B. & Urlaub, H. et al. (2016)
Nature Communications, 7 art. 11997. DOI: https://doi.org/10.1038/ncomms11997
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2017 | Journal Article
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
Bertram, K.; Agafonov, D. E.; Dybkov, O.; Haselbach, D.; Leelaram, M. N.; Will, C. L. & Urlaub, H. et al. (2017)
Cell, 170(4) pp. 701-713.e11. DOI: https://doi.org/10.1016/j.cell.2017.07.011
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2017 | Journal Article |
Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation
Sidarovich, A.; Will, C. L.; Anokhina, M. M.; Ceballos, J.; Sievers, S.; Agafonov, D. E. & Samatov, T. et al. (2017)
eLife, 6 art. e23533. DOI: https://doi.org/10.7554/eLife.23533
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2017 | Journal Article |
Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Bertram, K.; Agafonov, D. E.; Liu, W.-T.; Dybkov, O.; Will, C. L.; Hartmuth, K. & Urlaub, H. et al. (2017)
Nature, 542(7641) pp. 318. DOI: https://doi.org/10.1038/nature21079
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2018 | Journal Article
Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex
Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O. & Urlaub, H. et al. (2018)
Cell, 172(3) pp. 454-464.e11. DOI: https://doi.org/10.1016/j.cell.2018.01.010
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2020 | Journal Article
Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome
Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D. E.; Will, C. L.; Hartmuth, K. & Urlaub, H. et al. (2020)
Molecular Cell, 80(1) pp. 127-139.e6. DOI: https://doi.org/10.1016/j.molcel.2020.09.012
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2020 | Journal Article
Molecular architecture of the human 17S U2 snRNP
Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E. & Hofele, R. et al. (2020)
Nature, 583(7815) pp. 310-313. DOI: https://doi.org/10.1038/s41586-020-2344-3
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2020 | Journal Article
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation
Townsend, C.; Leelaram, M. N.; Agafonov, D. E.; Dybkov, O.; Will, C. L.; Bertram, K. & Urlaub, H. et al. (2020)
Science, 370(6523) art. eabc3753. DOI: https://doi.org/10.1126/science.abc3753
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2021 | Journal Article | Research Paper
Structure of a transcribing RNA polymerase II-U1 snRNP complex
Zhang, S.; Aibara, S.; Vos, S. M.; Agafonov, D. E.; Lührmann, R. & Cramer, P. (2021)
Science, 371(6526) pp. 305-309. DOI: https://doi.org/10.1126/science.abf1870
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2023 | Journal Article
Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins
Dybkov, O.; Preußner, M.; El Ayoubi, L.; Feng, V.-Y.; Harnisch, C.; Merz, K. & Leupold, P. et al. (2023)
Science Advances, 9(9) art. eadf1785. DOI: https://doi.org/10.1126/sciadv.adf1785
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