Author Hartmuth, Klaus
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2006 | Journal Article
Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions
Deckert, J.; Hartmuth, K.; Boehringer, D.; Behzadnia, N.; Will, C. L.; Kastner, B. & Stark, H. et al. (2006)
Molecular and Cellular Biology, 26(14) pp. 5528-5543. DOI: https://doi.org/10.1128/MCB.00582-06
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2007 | Journal Article
GraFix: sample preparation for single-particle electron cryomicroscopy
Kastner, B.; Fischer, N. ; Golas, M. M.; Sander, B.; Dube, P.; Boehringer, D. & Hartmuth, K. et al. (2007)
Nature Methods, 5(1) pp. 53-55. DOI: https://doi.org/10.1038/nmeth1139
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2007 | Journal Article
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes
Behzadnia, N.; Golas, M. M.; Hartmuth, K.; Sander, B.; Kastner, B.; Deckert, J. & Dube, P. et al. (2007)
The EMBO Journal, 26(6) pp. 1737-1748. DOI: https://doi.org/10.1038/sj.emboj.7601631
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2008 | Journal Article | Research Paper
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
Mathew, R.; Hartmuth, K.; Moehlmann, S.; Urlaub, H. ; Ficner, R. & Luehrmann, R. (2008)
Nature Structural & Molecular Biology, 15(5) pp. 435-443. DOI: https://doi.org/10.1038/nsmb.1415
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2016 | Journal Article
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A. & Kumar, V. et al. (2016)
Science, 353(6306) pp. 1399-1405. DOI: https://doi.org/10.1126/science.aag1906
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2017 | Journal Article |
Yeast Prp2 liberates the 5′ splice site and the branch site adenosine for catalysis of pre-mRNA splicing
Bao, P.; Höbartner, C. ; Hartmuth, K. & Lührmann, R. (2017)
RNA, 23(12) pp. 1770-1779. DOI: https://doi.org/10.1261/rna.063115.117
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2017 | Journal Article |
Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Bertram, K.; Agafonov, D. E.; Liu, W.-T.; Dybkov, O.; Will, C. L.; Hartmuth, K. & Urlaub, H. et al. (2017)
Nature, 542(7641) pp. 318. DOI: https://doi.org/10.1038/nature21079
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2018 | Journal Article
Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex
Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O. & Urlaub, H. et al. (2018)
Cell, 172(3) pp. 454-464.e11. DOI: https://doi.org/10.1016/j.cell.2018.01.010
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2020 | Journal Article
Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome
Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D. E.; Will, C. L.; Hartmuth, K. & Urlaub, H. et al. (2020)
Molecular Cell, 80(1) pp. 127-139.e6. DOI: https://doi.org/10.1016/j.molcel.2020.09.012
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