Author Klapper, Wolfram
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2006 | Journal Article
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling
Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F. E. & Bernd, H. W. et al. (2006)
New England Journal of Medicine, 354(23) pp. 2419-2430. DOI: https://doi.org/10.1056/NEJMoa055351
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2008 | Conference Abstract
Expression of intracellular ABC transporter A3 in aggressive non-Hodgkin lymphoma
Chapuy, B. ; Corsham, S.; Klapper, W.; Ziepert, M.; Truemper, L. H. & Wulf, G. (2008)
Annals of Oncology, 19 pp. 199-200. 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
Conserved oncogenic module activation patterns (COMAPS) identify biologically homogeneous groups of diffuse large B-cell lymphomas and clearly define Burkitt lymphoma
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Conference Abstract
Different subtypes of aggressive B cell lymphomas share an epigenetic signature enriched for polycomb targets in stem cells
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Klapper, W.; Wickham-Garcia, E. & Rosolowski, M. et al. (2008)
Annals of Oncology, 19 10th International Conference on Malignant Lymphoma, Lugano, SWITZERLAND.
Oxford: Oxford Univ Press.
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2008 | Journal Article | Research Paper |
Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration
Chapuy, B. ; Koch, R.; Radunski, U.; Corsham, S.; Cheong, N.; Inagaki, N. & Ban, N. et al. (2008)
Leukemia, 22(8) pp. 1576-1586. DOI: https://doi.org/10.1038/leu.2008.103
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2008 | Review
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma
Hoster, E.; Dreyling, M. H.; Klapper, W.; Gisselbrecht, C.; van Hoof, A.; Kluin-Nelemans, H. C.& Pfreundschuh, M. et al. (2008)
Blood, 111(2) pp. 558-565.
Amer Soc Hematology. DOI: https://doi.org/10.1182/blood-2007-06-095331
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2008 | Journal Article
Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
Klapper, W.; Stoecklein, H.; Zeynalova, S.; Ott, G.; Kosari, F.; Rosenwald, A. & Loeffler, M. et al. (2008)
Leukemia, 22(12) pp. 2226-2229. DOI: https://doi.org/10.1038/leu.2008.230
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2008 | Journal Article
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
Dierlamm, J.; Penas, E. M. M.; Bentink, S.; Wessendorf, S.; Berger, H.; Hummel, M. & Klapper, W. et al. (2008)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 93(5) pp. 688-696. DOI: https://doi.org/10.3324/haematol.12057
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2008 | Journal Article
Pathway activation patterns in diffuse large B-cell lymphomas
Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al. (2008)
Leukemia, 22(9) pp. 1746-1754. DOI: https://doi.org/10.1038/leu.2008.166
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2008 | Journal Article
Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials
Klapper, W.; Szczepanowski, M.; Burkhardt, B.; Berger, H.; Rosolowski, M.; Bentink, S. & Schwaenen, C. et al. (2008)
Blood, 112(4) pp. 1374-1381. DOI: https://doi.org/10.1182/blood-2008-01-136465
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2009 | Journal Article
The addition of rituximab to front-line therapy with CHOP (R-CHOP) results in a higher response rate and longer time to treatment failure in patients with lymphoplasmacytic lymphoma: results of a randomized trial of the German Low-Grade Lymphoma Study Group (GLSG)
Buske, C.; Hoster, E.; Dreyling, M.; Eimermacher, H.; Wandt, H.; Metzner, B. & Fuchs, R. et al. (2009)
Leukemia, 23(1) pp. 153-161. DOI: https://doi.org/10.1038/leu.2008.261
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2009 | Journal Article
Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular War Lymphoma Which Associate with Patient Survival and Gene Expression Status
Schwaenen, C.; Viardot, A.; Berger, H.; Barth, T. F. E.; Bentink, S.; Doehner, H. & Enz, M. et al. (2009)
Genes Chromosomes and Cancer, 48(1) pp. 39-54. DOI: https://doi.org/10.1002/gcc.20617
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2009 | Journal Article
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Ammerpohl, O.; Wickham-Garcia, E. & Rosolowski, M. et al. (2009)
Blood, 113(11) pp. 2488-2497. DOI: https://doi.org/10.1182/blood-2008-04-152900
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2009 | Journal Article |
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms.
Martin-Subero, J. I.; Ammerpohl, O.; Bibikova, M.; Wickham-Garcia, E.; Agirre, X.; Alvarez, S. & Brüggemann, M. et al. (2009)
PloS one, 4(9) art. e6986. DOI: https://doi.org/10.1371/journal.pone.0006986
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2009 | Journal Article |
Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
Bernd, H.-W.; Ziepert, M.; Thorns, C.; Klapper, W.; Wacker, H.-H.; Hummel, M. & Stein, H. et al. (2009)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 94(11) pp. 1569-1580. DOI: https://doi.org/10.3324/haematol.2009.008862
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2010 | Journal Article
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Ott, G.; Ziepert, M.; Klapper, W.; Horn, H.; Szczepanowski, M.; Bernd, H.-W. & Thorns, C. et al. (2010)
Blood, 116(23) pp. 4916-4925. DOI: https://doi.org/10.1182/blood-2010-03-276766
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2010 | Journal Article |
Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis
Scholtysik, R.; Kreuz, M.; Klapper, W.; Burkhardt, B.; Feller, A. C.; Hummel, M. & Loeffler, M. et al. (2010)
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(12) pp. 2047-2055. DOI: https://doi.org/10.3324/haematol.2010.026831
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2011 | Review
Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma
Deckert, M.; Engert, A.; Brueck, W.; Ferreri, A. J. M.; Finke, J.; Illerhaus, G.& Klapper, W. et al. (2011)
Leukemia, 25(12) pp. 1797-1807.
Nature Publishing Group. DOI: https://doi.org/10.1038/leu.2011.169
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2011 | Journal Article
Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
Salaverria, I.; Philipp, C.; Oschlies, I.; Kohler, C. W.; Kreuz, M.; Szczepanowski, M. & Burkhardt, B. et al. (2011)
Blood, 118(1) pp. 139-147. DOI: https://doi.org/10.1182/blood-2011-01-330795
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2012 | Conference Abstract
Sequencing of pediatric Burkitt lymphoma within the ICGC MMML-Seq project
Richter, J.; Schlesner, M.; Leich, E.; Burkhardt, B.; Hoffmann, S.; Szczepanowski, M. & Kreuz, M. et al. (2012)
British Journal of Haematology, 159 4th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkins Lymphoma, New York, NY.
Hoboken: Wiley-blackwell.
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