Author Linker, Ralf A.

• 2007 | Journal Article
  ​ ​Re-expression of a developmentally restricted potassium channel in autoimmune demyelination - Kv1.4 is implicated in oligodendroglial proliferation​
  Herrero-Herranz, E.; Pardo, L. A.; Bunt, G.; Gold, R.; Stühmer, W.   & Linker, R. A.​ (2007) 
  American Journal Of Pathology, 171(2) pp. 589​-598​.​ DOI: https://doi.org/10.2353/ajpath.2007.061241 
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• 2007 | Journal Article | Letter Note
  ​ ​Plasma exchange therapy for steroid-refractory superimposed relapses in secondary progressive multiple sclerosis​
  Linker, R. A.; Chan, A.; Sommer, M.; Koziolek, M.; Mueller, G.-A.; Paulus, W. J. & Gold, R.​ (2007) 
  Journal of Neurology, 254(9) pp. 1288​-1289​.​ DOI: https://doi.org/10.1007/s00415-006-0497-0 
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• 2008 | Journal Article
  ​ ​Leukemia Inhibitory Factor Deficiency Modulates the Immune Response and Limits Autoimmune Demyelination: A New Role for Neurotrophic Cytokines in Neuroinflammation​
  Linker, R. A.; Kruse, N.; Israel, S.; Wei, T.; Seubert, S.; Hombach, A. & Holtmann, B. et al.​ (2008) 
  The Journal of Immunology, 180(4) pp. 2204​-2213​.​ DOI: https://doi.org/10.4049/jimmunol.180.4.2204 
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• 2008 | Journal Article
  ​ ​Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: Long-term protective effects and enhanced efficacy of methylprednisolone formulations​
  Linker, R. A.; Weller, C.; Luehder, F.; Mohr, A.; Schmidt, J. ; Knauth, M. & Metselaar, J. M. et al.​ (2008) 
  Experimental Neurology, 211(2) pp. 397​-406​.​ DOI: https://doi.org/10.1016/j.expneurol.2008.02.005 
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• 2008 | Journal Article
  ​ ​Subcutaneous immunoglobulin infusion: A new therapeutic option in chronic inflammatory demyelinating polyneuropathy​
  Lee, D.-H.; Linker, R. A.; Paulus, W. J.; Schneider-Gold, C.; Chan, A. & Gold, R.​ (2008) 
  Muscle & Nerve, 37(3) pp. 406​-409​.​ DOI: https://doi.org/10.1002/mus.20909 
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• 2008 | Journal Article
  ​ ​IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier​
  Linker, R. A.; Luehder, F.; Kallen, K.-J.; Lee, D.-H.; Engelhardt, B.; Rose-John, S. & Gold, R.​ (2008) 
  Journal of Neuroimmunology, 205(1-2) pp. 64​-72​.​ DOI: https://doi.org/10.1016/j.jneuroim.2008.09.007 
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• 2009 | Review
  ​ ​Function of Neurotrophic Factors Beyond the Nervous System: Inflammation and Autoimmune Demyelination​
  Linker, R. A.; Gold, R.& Luehder, F.​ (2009)
  Critical Reviews in Immunology, 29​(1) pp. 43​-68​.​
  Begell House Inc.
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• 2009 | Journal Article | 
  ​ ​Proteome profiling in murine models of multiple sclerosis: identification of stage specific markers and culprits for tissue damage.​
  Linker, R. A.; Brechlin, P.; Jesse, S.; Steinacker, P.; Lee, D. H.; Asif, A. R. & Jahn, O.  et al.​ (2009) 
  PLoS One, 4(10) art. e7624​.​ DOI: https://doi.org/10.1371/journal.pone.0007624 
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• 2010 | Journal Article | 
  ​ ​Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis​
  Linker, R. A.; Lee, D.-H.; Demir, S.; Wiese, S.; Kruse, N.; Siglienti, I. & Gerhardt, E. et al.​ (2010) 
  Brain, 133 pp. 2248​-2263​.​ DOI: https://doi.org/10.1093/brain/awq179 
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• 2011 | Journal Article
  ​ ​Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway​
  Linker, R. A.; Lee, D.-H.; Ryan, S.; van Dam, A. M.; Conrad, R.; Bista, P. & Zeng, W. et al.​ (2011) 
  Brain, 134 pp. 678​-692​.​ DOI: https://doi.org/10.1093/brain/awq386 
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• 2012 | Journal Article
  ​ ​Neuronal NF-kappa B ablation does not influence neuro-axonal degeneration in experimental autoimmune demyelination​
  Lee, D.-H.; Kubera, K.; Rosenthal, B.; Kaltschmidt, B.; Kaltschmidt, C.; Gold, R. & Linker, R. A.​ (2012) 
  Journal of Neuroimmunology, 246(1-2) pp. 38​-42​.​ DOI: https://doi.org/10.1016/j.jneuroim.2012.03.005 
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• 2012 | Journal Article | 
  ​ ​Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination​
  Lee, D.-H.; Geyer, E.; Flach, A.-C. ; Jung, K.; Gold, R.; Fluegel, A. & Linker, R. A. et al.​ (2012) 
  Acta Neuropathologica, 123(2) pp. 247​-258​.​ DOI: https://doi.org/10.1007/s00401-011-0890-3 
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• 2012 | Journal Article | 
  ​ ​Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients​
  Jarius, S.; Ruprecht, K.; Wildemann, B.; Kuempfel, T.; Ringelstein, M.; Geis, C. & Kleiter, I. et al.​ (2012) 
  Journal of Neuroinflammation, 9 art. 14​.​ DOI: https://doi.org/10.1186/1742-2094-9-14 
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• 2012 | Journal Article
  ​ ​Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior​
  Peruga, I.; Hartwig, S.; Merkler, D.; Thoene, J.; Hovemann, B.; Juckel, G. & Gold, R. et al.​ (2012) 
  Behavioural Brain Research, 229(2) pp. 325​-332​.​ DOI: https://doi.org/10.1016/j.bbr.2012.01.020 
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• 2013 | Review
  ​ ​Brain-Derived Neurotrophic Factor in Neuroimmunology: Lessons Learned from Multiple Sclerosis Patients and Experimental Autoimmune Encephalomyelitis Models​
  Luehder, F.; Gold, R.; Fluegel, A.& Linker, R. A.​ (2013)
  Archivum Immunologiae et Therapiae Experimentalis, 61​(2) pp. 95​-105​.​
  Basel​: Springer. DOI: https://doi.org/10.1007/s00005-012-0211-0 
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• 2014 | Journal Article | 
  ​ ​Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease​
  Lee, D.-H.; Heidecke, H.; Schroeder, A.; Paul, F.; Wachter, R. R.; Hoffmann, R. & Ellrichmann, G. et al.​ (2014) 
  Molecular Neurodegeneration, 9 art. 49​.​ DOI: https://doi.org/10.1186/1750-1326-9-49 
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• 2015 | Journal Article
  ​ ​Thymocyte-derived BDNF influences T-cell maturation at the DN3/DN4 transition stage​
  Linker, R. A.; Lee, D.-H.; Flach, A.-C.; Litke, T. ; van den Brandt, J.; Reichardt, H. M. & Lingner, T. et al.​ (2015) 
  European Journal of Immunology, 45(5) pp. 1326​-1338​.​ DOI: https://doi.org/10.1002/eji.201444985 
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• 2016 | Journal Article
  ​ ​Pivotal Role for CD16(+) Monocytes in Immune Surveillance of the Central Nervous System​
  Waschbisch, A.; Schroeder, S.; Schraudner, D.; Sammet, L.; Weksler, B.; Melms, A. & Pfeifenbring, S. et al.​ (2016) 
  The Journal of Immunology, 196(4) pp. 1558​-1567​.​ DOI: https://doi.org/10.4049/jimmunol.1501960 
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