Author Outeiro, Tiago Fleming
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2022 | Journal Article
Type 2 Diabetes and Parkinson's Disease: A Focused Review of Current Concepts
Cullinane, P. W.; de Pablo Fernandez, E.; König, A.; Outeiro, T. F.; Jaunmuktane, Z. & Warner, T. T. (2022)
Movement Disorders, art. mds.29298. DOI: https://doi.org/10.1002/mds.29298
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2022 | Journal Article |
Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation
Lassen, L. B.; Thomsen, M. S.; Basso, E.; Füchtbauer, E.-M.; Füchtbauer, A.; Outeiro, T. F. & Jensen, P. H. et al. (2022)
Cells, 11(22) pp. 3673. DOI: https://doi.org/10.3390/cells11223673
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2023 | Journal Article
The immune system in Parkinson's disease: From biology to diagnosis and therapeutic targets
Outeiro, T. F. & El-Agnaf, O. M. (2023)
Neurobiology of Disease, 177 art. 105995. DOI: https://doi.org/10.1016/j.nbd.2023.105995
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2023 | Journal Article
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy
Xylaki, M.; Paiva, I.; Al-Azzani, M.; Gerhardt, E.; Jain, G.; Islam, M. R. & Vasili, E. et al. (2023)
Journal of Parkinson's Disease, pp. 1-18. DOI: https://doi.org/10.3233/JPD-225055
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2023 | Journal Article
Non-SUMOylated alternative spliced isoforms of alpha-synuclein are more aggregation-prone and toxic
Hassanzadeh, K.; Morrone, C.; Akhtari, K.; Gerhardt, E.; Zaccagnini, L.; Outeiro, T. F. & Feligioni, M. (2023)
Mechanisms of Ageing and Development, 209 art. 111759. DOI: https://doi.org/10.1016/j.mad.2022.111759
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2023 | Journal Article
People with Early Onset Parkinson’s Disease: Empowered to Improve Care
Domingos, J.; Teixeira Bastos, M. do C.; Couto, R.; Cameira, A. R.; Cardoso, A. L.; Reffóios, A. & Magalhães, S. et al. (2023)
Journal of Parkinson's Disease, pp. 1-4. DOI: https://doi.org/10.3233/JPD-230039
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2023 | Journal Article
RAGE Against the Glycation Machine in Synucleinopathies: Time to Explore New Questions
Gelain, D. P.; Bittencourt, R. R.; Bastos Mendes, L. F.; Moreira, J. C. F. & Outeiro, T. F. (2023)
Journal of Parkinson's Disease, pp. 1-12. DOI: https://doi.org/10.3233/JPD-230070
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2023 | Journal Article |
Stem Cell Therapies in Movement Disorders: Lessons from Clinical Trials
Marsili, L.; Sharma, J.; Outeiro, T. F. & Colosimo, C. (2023)
Biomedicines, 11(2) pp. 505. DOI: https://doi.org/10.3390/biomedicines11020505
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2023 | Journal Article | Overview
Is it all the RAGE ? Defining the role of the receptor for advanced glycation end products in Parkinson's disease
Gasparotto, J.; Somensi, N.; Girardi, C. S.; Bittencourt, R. R.; de Oliveira, L. M.; Hoefel, L. P. & Scheibel, I. M. et al. (2023)
Journal of Neurochemistry, art. jnc.15890. DOI: https://doi.org/10.1111/jnc.15890
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2023 | Journal Article | Overview
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies
Chopra, A. & Outeiro, T. F. (2023)
Brain, art. awad260. DOI: https://doi.org/10.1093/brain/awad260
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2023 | Journal Article
Increased alpha‐synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products ( RAGE )
Peixoto, D. O.; Bittencourt, R. R.; Gasparotto, J.; Kessler, F. G. C.; Brum, P. O.; Somensi, N. & Girardi, C. S. et al. (2023)
Journal of Neurochemistry, art. jnc.15956. DOI: https://doi.org/10.1111/jnc.15956
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2023 | Journal Article | Overview
PrP meets alpha‐synuclein: Molecular mechanisms and implications for disease
Vieira, T. C. R. G.; Barros, C. A.; Domingues, R. & Outeiro, T. F. (2023)
Journal of Neurochemistry, art. jnc.15992. DOI: https://doi.org/10.1111/jnc.15992
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2023 | Journal Article | Overview
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria
Klein, A. D. & Outeiro, T. F. (2023)
Nature Communications, 14(1). DOI: https://doi.org/10.1038/s41467-023-42107-7
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2023 | Journal Article
Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington’s Disease Effects in YAC128 Mice
Plácido, E.; Gomes Welter, P.; Wink, A.; Karasiak, G. D.; Outeiro, T. F.; Dafre, A. L. & Gil-Mohapel, J. et al. (2023)
International Journal of Molecular Sciences, 24(16) art. 12607. DOI: https://doi.org/10.3390/ijms241612607
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2023 | Journal Article
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease
Brembati, V.; Faustini, G.; Longhena, F.; Outeiro, T. F. & Bellucci, A. (2023)
International Journal of Molecular Sciences, 24(17) art. 13435. DOI: https://doi.org/10.3390/ijms241713435
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2023 | Journal Article | Overview
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
Flores-Leon, M. & Outeiro, T. F. (2023)
Acta Neuropathologica, 146(3) pp. 369-385. DOI: https://doi.org/10.1007/s00401-023-02601-0
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2023 | Journal Article |
Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation
Gatzemeier, L. M.; Meyer, F.; Diederichsen, U. & Outeiro, T. F. (2023)
Chemistry: a European Journal, 29(33) art. e202300649. DOI: https://doi.org/10.1002/chem.202300649
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2024 | Journal Article
In silico analysis of alpha‐synuclein protein variants and posttranslational modifications related to Parkinson's disease
da Silva, A. N. R.; Pereira, G. R. C.; Bonet, L. F. S.; Outeiro, T. F. & De Mesquita, J. F. (2024)
Journal of Cellular Biochemistry, art. jcb.30523. DOI: https://doi.org/10.1002/jcb.30523
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