Author Ryazanov, Sergey

1 to 9 of 9 Items
  • 2015 | Journal Article
    ​ ​The Novel Inhibitor “Anle145C” Efficiently Inhibits Fibril Formation of Islet Amyloid Polypeptide (IAPP) and uses Distinctly Different Modes of Action in the Absence and Presence of Membranes​
    Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Seeliger, J.; Winter, R.; Giese, A. & Griesinger, C.  et al.​ (2015) 
    Biophysical Journal, 108(2) pp. 256a​.​ DOI: https://doi.org/10.1016/j.bpj.2014.11.1416 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​The Small Molecule anle138b Shows Interaction with α-Synuclein Oligomers in Phospholipid Membranes​
    Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al.​ (2018) 
    Biophysical Journal, 114(3) pp. 560a​.​ DOI: https://doi.org/10.1016/j.bpj.2017.11.3064 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Protein-Drug Interactions in the Membrane: The Small Molecule Anle138b and its Binding to α-Synuclein Oligomers​
    Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al.​ (2019) 
    Biophysical Journal, 116(3) pp. 352a​.​ DOI: https://doi.org/10.1016/j.bpj.2018.11.1913 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes​
    Ghio, S.; Camilleri, A.; Caruana, M.; Ruf, V. C.; Schmidt, F.; Leonov, A. & Ryazanov, S. et al.​ (2019) 
    ACS Chemical Neuroscience, 10(8) pp. 3815​-3829​.​ DOI: https://doi.org/10.1021/acschemneuro.9b00320 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy​
    Heras-Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C. ; Giese, A. & Wenning, G. K. et al.​ (2019) 
    Movement Disorders, 34(2) pp. 255​-263​.​ DOI: https://doi.org/10.1002/mds.27562 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin​
    Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F. & Leonov, A. et al.​ (2020) 
    Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862(2) art. S000527361930210X​.​ DOI: https://doi.org/10.1016/j.bbamem.2019.183064 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance​
    Lemos, M.; Venezia, S.; Refolo, V.; Heras-Garvin, A.; Schmidhuber, S.; Giese, A. & Leonov, A. et al.​ (2020) 
    Translational Neurodegeneration, 9(1) art. 38​.​ DOI: https://doi.org/10.1186/s40035-020-00217-y 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier​
    Maurer, A.; Leonov, A.; Ryazanov, S.; Herfert, K.; Kuebler, L.; Buss, S. & Schmidt, F. et al.​ (2020) 
    ChemMedChem, 15(5) pp. 411​-415​.​ DOI: https://doi.org/10.1002/cmdc.201900689 
    ​Details  DOI  PMID  PMC 
  • 2023 | Journal Article
    ​ ​Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR​
    Dervişoğlu, R.; Antonschmidt, L.; Nimerovsky, E.; Sant, V.; Kim, M.; Ryazanov, S. & Leonov, A. et al.​ (2023) 
    Methods,.​ DOI: https://doi.org/10.1016/j.ymeth.2023.04.002 
    ​Details  DOI  PMID  PMC 

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