Items 11-20 of 25
Effects of Two Guideline Implementation Strategies on Patient Outcomes in Primary Care
Study design: Cluster randomized controlled trial Objective: To improve quality of care for patients with low back pain (LBP) a multifaceted general practitioner education alone and in combination with motivational ...
Time will tell: Deficits of temporal-information processing in patients with visual field loss
Visual field loss after brain lesions is commonly determined using perimetric tests of light detection (perimetry). Many patients with visual field defects complain about perceptual difficulties in areas that are ...
Filtration of protein aggregates increases the accuracy for diagnosing prion diseases in brain biopsies.
In brain biopsies taken from patients with rapidly progressive dementia, the first differential diagnoses to be ruled out are prion diseases. For safe diagnostic processing of tissue and instruments, a rapid, highly ...
Favorable impact of the interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial.
BACKGROUND: Recently published data indicate that host germline variations in immune genes can influence the outcome of lymphoma patients. Interleukin (IL)-4 and IL13 are crucial immune factors and may influence the course ...
An antidote for calcium leak: targeting molecular arrhythmia mechanisms.
Detection of classical and atypical/Nor98 scrapie by the paraffin-embedded tissue blot method.
The paraffin-embedded tissue (PET) blot method was used to investigate sections of the central nervous system and lymphatic tissues from 24 cases of classical scrapie and 25 cases of atypical/Nor98 scrapie in sheep and ...
Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few studies
BACKGROUND: Random-effects meta-analysis is commonly performed by first deriving an estimate of the between-study variation, the heterogeneity, and subsequently using this as the basis for combining results, i.e., for ...
Explaining temporal trends in annualised relapse rates in placebo groups of randomised controlled trials in relapsing multiple sclerosis: systematic review and meta-regression
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS). Methods: We conducted a systematic ...
Model averaging for robust extrapolation in evidence synthesis
Extrapolation from a source to a target, e.g., from adults to children, is a promising approach to utilizing external information when data are sparse. In the context of meta-analysis, one is commonly faced with a small ...