Author Moll, Ute M.

21 to 29 of 29 Items
  • 2014 | Journal Article
    ​ ​Targeting tumour-supportive cellular machineries in anticancer drug development​
    Dobbelstein, M.   & Moll, U. M.​ (2014) 
    Nature Reviews Drug Discovery, 13(3) pp. 179​-196​.​ DOI: https://doi.org/10.1038/nrd4201 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | 
    ​ ​Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment​
    Alexandrova, E. M.; Yallowitz, A. R.; Li, D.; Xu, S.; Schulz, R.; Proia, D. A. & Lozano, G. et al.​ (2015) 
    Nature, 523(7560) pp. 352​-+​.​ DOI: https://doi.org/10.1038/nature14430 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​TAp73 is a central transcriptional regulator of airway multiciliogenesis​
    Nemajerova, A.; Kramer, D.; Siller, S. S.; Herr, C.; Shomroni, O.; Pena, T. & Suazo, C. G. et al.​ (2016) 
    Genes & Development, 30(11) pp. 1300​-1312​.​ DOI: https://doi.org/10.1101/gad.279836.116 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53​
    Wienken, M.; Dickmanns, A.; Nemajerova, A.; Kramer, D.; Najafova, Z.; Weiss, M. & Karpiuk, O. et al.​ (2016) 
    Molecular Cell, 61(1) pp. 68​-83​.​ DOI: https://doi.org/10.1016/j.molcel.2015.12.008 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells​
    Kramer, D.; Stark, N. ; Schulz-Heddergott, R.; Erytch, N.; Edmunds, S.; Rossmann, L.   & Bastians, H. et al.​ (2017) 
    Cell Death and Differentiation, 24(2) pp. 300​-316​.​ DOI: https://doi.org/10.1038/cdd.2016.124 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo​
    Alexandrova, E. M.; Mirza, S. A.; Xu, S.; Schulz-Heddergott, R.; Marchenko, N. D. & Moll, U. M.​ (2017) 
    Cell Death and Disease, 8 art. e2661​.​ DOI: https://doi.org/10.1038/cddis.2017.80 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Review
    ​ ​Mdm2 as a chromatin modifier​
    Wienken, M.; Moll, U. M.& Dobbelstein, M. ​ (2017)
    Journal of Molecular Cell Biology, 9​(1) pp. 74​-80​.​
    Oxford Univ Press. DOI: https://doi.org/10.1093/jmcb/mjw046 
    ​Details  DOI  PMID  PMC  WoS 
  • 2018 | Journal Article | 
    ​ ​Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target​
    Schulz-Heddergott, R. & Moll, U. M.​ (2018) 
    Cancers, 10(6).​ DOI: https://doi.org/10.3390/cancers10060188 
    ​Details  DOI  PMID  PMC 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity​
    Isermann, T.; Şener, Ö. Ç.; Stender, A.; Klemke, L.; Winkler, N.; Neesse, A. & Li, J. et al.​ (2021) 
    Nature Communications, 12(1) art. 4019​.​ DOI: https://doi.org/10.1038/s41467-021-24064-1 
    ​Details  DOI 

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