Prof. Dr. med. Matthias Dobbelstein

 
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  • 2023 Journal Article | 
    ​ ​N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody​
    Zibat, A.; Zhang, X.; Dickmanns, A.; Stegmann, K. M.; Dobbelstein, A. W.; Alachram, H. & Soliwoda, R. et al.​ (2023) 
    iScience26(10) art. 107786​.​ DOI: https://doi.org/10.1016/j.isci.2023.107786 
    Details  DOI 
  • 2022 Journal Article | 
    ​ ​Therapeutische Nanobodies gegen SARS-CoV-2​
    Güttler, T.; Dobbelstein, M.   & Görlich, D.​ (2022) 
    BIOspektrum28(1) pp. 39​-42​.​ DOI: https://doi.org/10.1007/s12268-022-1684-y 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression​
    Giansanti, C.; Manzini, V.; Dickmanns, A.; Dickmanns, A. ; Palumbieri, M. D.; Sanchi, A. & Kienle, S. M. et al.​ (2022) 
    Cell Reports39(9) art. 110879​.​ DOI: https://doi.org/10.1016/j.celrep.2022.110879 
    Details  DOI 
  • 2022 Journal Article | Research Paper | 
    ​ ​Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication​
    Stegmann, K. M.; Dickmanns, A.; Heinen, N.; Blaurock, C.; Karrasch, T.; Breithaupt, A. & Klopfleisch, R. et al.​ (2022) 
    iScience25(5) art. S2589004222005636​.​ DOI: https://doi.org/10.1016/j.isci.2022.104293 
    Details  DOI 
  • 2021 Journal Article
    ​ ​The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models​
    Stegmann, K. M.; Dickmanns, A.; Gerber, S.; Nikolova, V.; Klemke, L.; Manzini, V. & Schlösser, D. et al.​ (2021) 
    Virus Research302 art. S0168170221001763​.​ DOI: https://doi.org/10.1016/j.virusres.2021.198469 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​MDM2-Driven Ubiquitination Rapidly Removes p53 from Its Cognate Promoters​
    Henningsen, K. M.; Manzini, V.; Magerhans, A.; Gerber, S. & Dobbelstein, M. ​ (2021) 
    Biomolecules12(1) pp. 22​.​ DOI: https://doi.org/10.3390/biom12010022 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​HSP90 Inhibition Synergizes with Cisplatin to Eliminate Basal-like Pancreatic Ductal Adenocarcinoma Cells​
    Ewers, K. M.; Patil, S.; Kopp, W.; Thomale, J.; Quilitz, T.; Magerhans, A. & Wang, X. et al.​ (2021) 
    Cancers13(24) pp. 6163​.​ DOI: https://doi.org/10.3390/cancers13246163 
    Details  DOI 
  • 2021 Journal Article | 
    ​ ​Neutralization of SARS‐CoV‐2 by highly potent, hyperthermostable, and mutation‐tolerant nanobodies​
    Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R. & Taxer, W. et al.​ (2021) 
    The EMBO Journal40(19).​ DOI: https://doi.org/10.15252/embj.2021107985 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Mdm2: Open questions​
    Dobbelstein, M.   & Levine, A. J.​ (2020) 
    Cancer Science111(7) pp. 2203​-2211​.​ DOI: https://doi.org/10.1111/cas.14433 
    Details  DOI 
  • 2020 Journal Article
    ​ ​Mdm4 supports DNA replication in a p53-independent fashion​
    Wohlberedt, K.; Klusmann, I.; Derevyanko, P. K.; Henningsen, K.; Choo, J. A. M. Y.; Manzini, V. & Magerhans, A. et al.​ (2020) 
    Oncogene39(25) pp. 4828​-4843​.​ DOI: https://doi.org/10.1038/s41388-020-1325-1 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis​
    Müller, A.; Dickmanns, A.; Resch, C.; Schäkel, K.; Hailfinger, S.; Dobbelstein, M.   & Schulze-Osthoff, K. et al.​ (2020) 
    Journal of Clinical Investigation130(11) pp. 5765​-5781​.​ DOI: https://doi.org/10.1172/JCI134217 
    Details  DOI 
  • 2020 Journal Article | Erratum | 
    ​ ​Correction: The integrated stress response induces R-loops and hinders replication fork progression​
    Choo, J. A. M. Y.; Schlösser, D.; Manzini, V.; Magerhans, A. & Dobbelstein, M. ​ (2020) 
    Cell Death & Disease11(7).​ DOI: https://doi.org/10.1038/s41419-020-02817-y 
    Details  DOI 
  • 2020 Journal Article | 
    ​ ​The integrated stress response induces R-loops and hinders replication fork progression​
    Choo, J. A. M. Y.; Schlösser, D.; Manzini, V.; Magerhans, A. & Dobbelstein, M. ​ (2020) 
    Cell Death & Disease11(7).​ DOI: https://doi.org/10.1038/s41419-020-2727-2 
    Details  DOI 
  • 2019 Journal Article
    ​ ​Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase​
    Herold, S.; Kalb, J.; Büchel, G.; Ade, C. P.; Baluapuri, A.; Xu, J. & Koster, J. et al.​ (2019) 
    Nature567(7749) pp. 545​-549​.​ DOI: https://doi.org/10.1038/s41586-019-1030-9 
    Details  DOI 
  • 2019 Journal Article
    ​ ​EUDARIO/ENGOTov-48: A European multicenter randomised phase II trial on the combination of the HSP90 inhibitor ganetespib with carboplatin followed by maintenance treatment with niraparib (+/- ganetespib) compared to platinum-based combination-chemotherapy followed by niraparib in relapsed platinum-sensitive ovarian cancer patients.​
    Concin, N.; Lorusso, D.; Braicu, I.; Ray-Coquard, I. L.; Joly, F.; Harter, P. & Wimberger, P. et al.​ (2019) 
    Journal of Clinical Oncology37(15_suppl) pp. TPS5605​-TPS5605​.​ DOI: https://doi.org/10.1200/JCO.2019.37.15_suppl.TPS5605 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Inhibition of MAPKAPK2/MK2 facilitates DNA replication upon cancer cell treatment with gemcitabine but not cisplatin​
    Li, Y.; Köpper, F. & Dobbelstein, M. ​ (2018) 
    Cancer Letters428 pp. 45​-54​.​ DOI: https://doi.org/10.1016/j.canlet.2018.04.030 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion​
    Schulz-Heddergott, R. ; Stark, N. ; Edmunds, S. J. ; Li, J.; Conradi, L.-C. ; Bohnenberger, H.   & Ceteci, F. et al.​ (2018) 
    Cancer Cell34(2) pp. 298​-314.e7​.​ DOI: https://doi.org/10.1016/j.ccell.2018.07.004 
    Details  DOI 
  • 2018 Journal Article
    ​ ​Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication​
    Klusmann, I.; Wohlberedt, K.; Magerhans, A.; Teloni, F.; Korbel, J. O.; Altmeyer, M. & Dobbelstein, M. ​ (2018) 
    Proceedings of the National Academy of Sciences115(48) pp. E11311​-E11320​.​ DOI: https://doi.org/10.1073/pnas.1809592115 
    Details  DOI 
  • 2018 Journal Article | Erratum | 
    ​ ​Correction: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells​
    Kramer, D. ; Stark, N. ; Schulz-Heddergott, R. ; Erytch, N.; Edmunds, S. ; Roßmann, L.   & Bastians, H.  et al.​ (2018) 
    Cell Death and Differentiation26(4) pp. 780​-780​.​ DOI: https://doi.org/10.1038/s41418-018-0190-8 
    Details  DOI 
  • 2018 Journal Article | 
    ​ ​CDK4 inhibition diminishes p53 activation by MDM2 antagonists​
    Sriraman, A.; Dickmanns, A.; Najafova, Z.; Johnsen, S. A. & Dobbelstein, M. ​ (2018) 
    Cell Death & Disease9(9) art. 918​.​ DOI: https://doi.org/10.1038/s41419-018-0968-0 
    Details  DOI  PMID  PMC 
  • 2017 Journal Article | 
    ​ ​Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells​
    Kramer, D.; Stark, N. ; Schulz-Heddergott, R.; Erytch, N.; Edmunds, S.; Rossmann, L.   & Bastians, H. et al.​ (2017) 
    Cell Death and Differentiation24(2) pp. 300​-316​.​ DOI: https://doi.org/10.1038/cdd.2016.124 
    Details  DOI  PMID  PMC  WoS 
  • 2017 Review
    ​ ​Mdm2 as a chromatin modifier​
    Wienken, M.; Moll, U. M.& Dobbelstein, M. ​ (2017)
    Journal of Molecular Cell Biology, 9​(1) pp. 74​-80​.​
    Oxford Univ Press. DOI: https://doi.org/10.1093/jmcb/mjw046 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53​
    Wienken, M.; Dickmanns, A.; Nemajerova, A.; Kramer, D.; Najafova, Z.; Weiss, M. & Karpiuk, O. et al.​ (2016) 
    Molecular Cell61(1) pp. 68​-83​.​ DOI: https://doi.org/10.1016/j.molcel.2015.12.008 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death​
    Beyer, U.; Kroenung, S. K.; Leha, A.; Walter, L. & Dobbelstein, M. ​ (2016) 
    Cell Death and Differentiation23(1) pp. 64​-75​.​ DOI: https://doi.org/10.1038/cdd.2015.68 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article
    ​ ​Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness​
    Kari, V.; Mansour, W. Y.; Raul, S. K.; Baumgart, S. J. ; Mund, A.; Grade, M. & Sirma, H. et al.​ (2016) 
    EMBO Reports17(11) pp. 1609​-1623​.​ DOI: https://doi.org/10.15252/embr.201642352 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition​
    Kronung, S. K.; Beyer, U.; Chiaramonte, M. L.; Dolfini, D.; Mantovani, R. & Dobbelstein, M. ​ (2016) 
    Oncotarget7(23) pp. 33484​-33497​.​ DOI: https://doi.org/10.18632/oncotarget.9255 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​p53 Activity Results in DNA Replication Fork Processivity​
    Klusmann, I.; Rodewald, S.; Mueller, L.; Friedrich, M.; Wienken, M.; Li, Y. & Schulz-Heddergott, R.  et al.​ (2016) 
    Cell Reports17(7) pp. 1845​-1857​.​ DOI: https://doi.org/10.1016/j.celrep.2016.10.036 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | Letter Note
    ​ ​Fortifying p53-beyond Mdm2 inhibitors​
    Sriraman, A.; Li, Y. & Dobbelstein, M. ​ (2016) 
    Aging8(9) pp. 1836​-1837​.​ DOI: https://doi.org/10.18632/aging.101073 
    Details  DOI  PMID  PMC  WoS 
  • 2016 Journal Article | 
    ​ ​Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity​
    Sriraman, A.; Radovanovic, M.; Wienken, M.; Najafova, Z.; Li, Y. & Dobbelstein, M. ​ (2016) 
    Oncotarget7(22) pp. 31623​-31638​.​ DOI: https://doi.org/10.18632/oncotarget.9302 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Usp22 deficiency impairs intestinal epithelial lineage specification in vivo.​
    Kosinsky, R. L.; Wegwitz, F.; Hellbach, N.; Dobbelstein, M. ; Mansouri, A.; Vogel, T. & Begus-Nahrmann, Y. et al.​ (2015) 
    Oncotarget6(35) pp. 37906​-37918​.​ DOI: https://doi.org/10.18632/oncotarget.5412 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | 
    ​ ​5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.​
    Srinivas, U. S.; Dyczkowski, J.; Beißbarth, T. ; Gaedcke, J. ; Mansour, W. Y.; Borgmann, K. & Dobbelstein, M. ​ (2015) 
    Oncotarget6(14) pp. 12574​-12586​.​ DOI: https://doi.org/10.18632/oncotarget.3728 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | Erratum | 
    ​ ​Erratum: Corrigendum: Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment​
    Alexandrova, E. M.; Yallowitz, A. R.; Li, D.; Xu, S.; Schulz, R.; Proia, D. A. & Lozano, G. et al.​ (2015) 
    Nature527(7578) pp. 398​-398​.​ DOI: https://doi.org/10.1038/nature15720 
    Details  DOI 
  • 2015 Journal Article | 
    ​ ​Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells​
    Schmidt, F.; Kunze, M.; Loock, A.-C. & Dobbelstein, M. ​ (2015) 
    Oncotarget6(2) pp. 617​-632​.​
    Details  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors​
    Li, Y.; Saini, P.; Sriraman, A. & Dobbelstein, M. ​ (2015) 
    Oncotarget6(32) pp. 32339​-32352​.​ DOI: https://doi.org/10.18632/oncotarget.5891 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment​
    Alexandrova, E. M.; Yallowitz, A. R.; Li, D.; Xu, S.; Schulz, R.; Proia, D. A. & Lozano, G. et al.​ (2015) 
    Nature523(7560) pp. 352​-+​.​ DOI: https://doi.org/10.1038/nature14430 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Review
    ​ ​Exploiting replicative stress to treat cancer​
    Dobbelstein, M.  & Sorensen, C. S.​ (2015)
    Nature Reviews Drug Discovery, 14​(6) pp. 405​-423​.​
    Nature Publishing Group. DOI: https://doi.org/10.1038/nrd4553 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | 
    ​ ​Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress.​
    Saini, P.; Li, Y. & Dobbelstein, M. ​ (2015) 
    Oncotarget6(15) pp. 13072​-13087​.​ DOI: https://doi.org/10.18632/oncotarget.3865 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Letter Note
    ​ ​G2E3 attenuating replicative stress​
    Schmidt, F.; Karnitz, L. M. & Dobbelstein, M. ​ (2015) 
    Aging7(8) pp. 527​-528​.​ DOI: https://doi.org/10.18632/aging.100784 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article | Research Paper | 
    ​ ​Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice​
    Gogiraju, R.; Xu, X.; Bochenek, M. L.; Steinbrecher, J. H.; Lehnart, S. E. ; Wenzel, P. & Kessel, M.  et al.​ (2015) 
    Journal of the American Heart Association4(2) art. e001770​.​ DOI: https://doi.org/10.1161/JAHA.115.001770 
    Details  DOI  PMID  PMC 
  • 2015 Journal Article | 
    ​ ​A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity​
    Kramer, D.; Schoen, M.; Bayerlova, M.; Bleckmann, A.; Schoen, M. P.; Zoernig, M. & Dobbelstein, M. ​ (2015) 
    Cell Death and Disease6 art. e1634​.​ DOI: https://doi.org/10.1038/cddis.2015.17 
    Details  DOI  PMID  PMC  WoS 
  • 2015 Journal Article
    ​ ​MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP​
    Zhang, X.; Schulz, R.; Edmunds, S. ; Krueger, E.; Markert, E.; Gaedcke, J.   & Cormet-Boyaka, E. et al.​ (2015) 
    Molecular Cell59(2) pp. 243​-257​.​ DOI: https://doi.org/10.1016/j.molcel.2015.05.036 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article
    ​ ​Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells​
    Schmidt, F.; Kunze, M.; Loock, A.-C. & Dobbelstein, M. ​ (2014) 
    Oncotarget6(2) pp. 617​-632​.​ DOI: https://doi.org/10.18632/oncotarget.2710 
    Details  DOI 
  • 2014 Conference Abstract
    ​ ​microRNA-449 acts as a barrier to stemness​
    Suazo, C. G.; Klimke, A.; Lize, M.; Kessel, M. & Dobbelstein, M. ​ (2014)
    European Journal of Cancer50 
    Oxford​: Elsevier Sci Ltd.
    Details  WoS 
  • 2014 Journal Article | 
    ​ ​Overcoming EMT-driven therapeutic resistance by BH3 mimetics.​
    Keitel, U.; Scheel, C. & Dobbelstein, M. ​ (2014) 
    Oncoscience1(11) pp. 706​-708​.​
    Details  PMID  PMC 
  • 2014 Journal Article
    ​ ​The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells​
    Koepper, F.; Binkowski, A. M.; Bierwirth, C. & Dobbelstein, M. ​ (2014) 
    Cell Cycle13(6) pp. 884​-889​.​ DOI: https://doi.org/10.4161/cc.28292 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article
    ​ ​TAp73 is essential for germ cell adhesion and maturation in testis​
    Holembowski, L.; Kramer, D. ; Riedel, D.; Sordella, R.; Nemajerova, A.; Dobbelstein, M.   & Moll, U. M.​ (2014) 
    The Journal of Cell Biology204(7) pp. 1173​-1190​.​ DOI: https://doi.org/10.1083/jcb.201306066 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | 
    ​ ​HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer​
    Schulz, R.; Streller, F.; Scheel, A. H.; Rueschoff, J.; Reinert, M. C.; Dobbelstein, M.   & Marchenko, N. D. et al.​ (2014) 
    Cell Death and Disease5 art. e980​.​ DOI: https://doi.org/10.1038/cddis.2013.508 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | 
    ​ ​Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation​
    Keitel, U.; Scheel, A.; Thomale, J.; Halpape, R.; Kaulfuß, S.; Scheel, C. & Dobbelstein, M. ​ (2014) 
    Oncotarget5(23) pp. 11778​-11791​.​ DOI: https://doi.org/10.18632/oncotarget.2634 
    Details  DOI  PMID  PMC 
  • 2014 Journal Article
    ​ ​Targeting tumour-supportive cellular machineries in anticancer drug development​
    Dobbelstein, M.   & Moll, U. M.​ (2014) 
    Nature Reviews Drug Discovery13(3) pp. 179​-196​.​ DOI: https://doi.org/10.1038/nrd4201 
    Details  DOI  PMID  PMC  WoS 
  • 2014 Journal Article | 
    ​ ​UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib​
    Landmann, H.; Proia, D. A.; He, S.; Ogden, F. L.; Kramer, F.-J. ; Beißbarth, T.   & Grade, M.  et al.​ (2014) 
    Cell Death and Disease5 art. e1411​.​ DOI: https://doi.org/10.1038/cddis.2014.378 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Conference Abstract
    ​ ​Importance of tumor suppressor gene p53-mediated endothelial cell apoptosis for cardiac angiogenesis and hypertrophy​
    Gogiraju, R.; Steinbrecher, J. H.; Lehnart, S. E. ; Kessel, M.; Dobbelstein, M.   & Schaefer, K.​ (2013)
    European Heart Journal34 , Amsterdam, NETHERLANDS.
    Oxford​: Oxford Univ Press.
    Details  WoS 
  • 2013 Conference Abstract
    ​ ​Protein Tyrosine Kinase 7 (PTK7): A Novel "Molecular Switch" Regulating Differentiation Fate of Human Skeletal (Mesenchymal) Stem Cells into Osteoblasts versus Adipocytes​
    Jafari, A.; Siersbaek, M. S.; Larsen, K.; Dobbelstein, M.   & Kassem, M.​ (2013)
    Journal of Bone and Mineral Research28 ​Annual Meeting of the American-Society-for-Bone-and-Mineral-Research​, Baltimore, MD.
    Hoboken​: Wiley-blackwell.
    Details  WoS 
  • 2013 Journal Article
    ​ ​Interchanging heads: p53 re-composes the DREAM/MMB complex to repress transcription​
    Dobbelstein, M. ​ (2013) 
    Cell Cycle12(1) pp. 11​-12​.​ DOI: https://doi.org/10.4161/cc.22917 
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  • 2013 Conference Paper
    ​ ​Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a,-224,-132 and let7g​
    Salendo, J. ; Spitzner, M. ; Kramer, F. ; Zhang, X.; Jo, P. ; Wolff, H. A.   & Kitz, J.  et al.​ (2013)
    Radiotherapy and Oncology108(3) pp. 451​-457. ​13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology​, Ermatingen, SWITZERLAND.
    Clare​: Elsevier Ireland Ltd. DOI: https://doi.org/10.1016/j.radonc.2013.06.032 
    Details  DOI  PMID  PMC  WoS 
  • 2013 Journal Article
    ​ ​Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity​
    Koepper, F.; Bierwirth, C.; Schoen, M.; Kunze, M.; Elvers, I.; Kranz, D. & Saini, P. et al.​ (2013) 
    Proceedings of the National Academy of Sciences of the United States of America110(42) pp. 16856​-16861​.​ DOI: https://doi.org/10.1073/pnas.1304355110 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article
    ​ ​Interchanging heads​
    Dobbelstein, M. ​ (2012) 
    Cell Cycle12(1) pp. 11​-11​.​ DOI: https://doi.org/10.4161/cc.23169 
    Details  DOI 
  • 2012 Journal Article
    ​ ​HSP90 inhibitor antagonizing MIF The specifics of pleiotropic cancer drug candidates​
    Schulz, R.; Dobbelstein, M.   & Moll, U. M.​ (2012) 
    OncoImmunology1(8) pp. 1425​-1426​.​ DOI: https://doi.org/10.4161/onci.21173 
    Details  DOI  WoS 
  • 2012 Journal Article
    ​ ​A killer promoting survival: p53 as a selective means to avoid side effects of chemotherapy​
    Kranz, D. & Dobbelstein, M. ​ (2012) 
    Cell Cycle11(11) pp. 2053​-2054​.​ DOI: https://doi.org/10.4161/cc.20698 
    Details  DOI 
  • 2012 Journal Article
    ​ ​Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression​
    Schulz, R.; Marchenko, N. D.; Holembowski, L.; Fingerle-Rowson, G.; Pesic, M.; Zender, L. & Dobbelstein, M.  et al.​ (2012) 
    Journal of Experimental Medicine209(3) pp. 640​-640​.​ DOI: https://doi.org/10.1084/jem.201111172093c 
    Details  DOI 
  • 2012 Journal Article | 
    ​ ​Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression​
    Schulz, R.; Marchenko, N. D.; Holembowski, L.; Fingerle-Rowson, G.; Pesic, M.; Zender, L. & Dobbelstein, M.  et al.​ (2012) 
    Journal of Experimental Medicine209(2) pp. 275​-289​.​ DOI: https://doi.org/10.1084/jem.20111117 
    Details  DOI  PMID  PMC  WoS 
  • 2012 Journal Article
    ​ ​Doxorubicin-induced activation of NF-kappa B in melanoma cells is abrogated by inhibition of IKK beta, but not by a novel IKK alpha inhibitor​
    Pletz, N.; Schoen, M.; Ziegelbauer, K.; Emmert, S.; Liu, N.; Dobbelstein, M.   & Schoen, M. P.​ (2012) 
    Experimental Dermatology21(4) pp. 301​-304​.​ DOI: https://doi.org/10.1111/j.1600-0625.2012.01440.x 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Conference Abstract
    ​ ​Doxorubicin-induced activation of NF-kappa B in melanoma cells is abrogated by specific inhibition of IKK beta, but not IKK alpha​
    Pletz, N.; Schoen, M. P.; Ziegelbauer, K.; Emmert, S.; Liu, N.; Dobbelstein, M.   & Schoen, M.​ (2011)
    Journal of Investigative Dermatology131 ​41st Annual Meeting of the European-Society-for-Dermatological-Research​, Barcelona, SPAIN.
    New york​: Nature Publishing Group.
    Details  WoS 
  • 2011 Conference Abstract
    ​ ​Identification of p53 regulatory microRNAs​
    Zhang, X. & Dobbelstein, M. ​ (2011)
    Cancer Research71 
    Philadelphia​: Amer Assoc Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2011-1186 
    Details  DOI  WoS 
  • 2011 Journal Article
    ​ ​Anthracyclines induce the accumulation of mutant p53 through E2F1-dependent and -independent mechanisms​
    Bug, M. & Dobbelstein, M. ​ (2011) 
    Oncogene30(33) pp. 3612​-3624​.​ DOI: https://doi.org/10.1038/onc.2011.72 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes​
    Beyer, U.; Moll-Rocek, J.; Moll, U. M. & Dobbelstein, M. ​ (2011) 
    Proceedings of the National Academy of Sciences of the United States of America108(9) pp. 3624​-3629​.​ DOI: https://doi.org/10.1073/pnas.1016201108 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​While p73 is essential, p63 is completely dispensable for the development of the central nervous system​
    Holembowski, L.; Schulz, R.; Talos, F.; Scheel, A.; Holzman, S.; Dobbelstein, M.   & Moll, U. M.​ (2011) 
    Cell Cycle10(4) pp. 680​-689​.​ DOI: https://doi.org/10.4161/cc.10.4.14859 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Review
    ​ ​MicroRNA-449 in cell fate determination​
    Lize, M.; Klimke, A.& Dobbelstein, M. ​ (2011)
    Cell Cycle, 10​(17) pp. 2874​-2882​.​
    Landes Bioscience. DOI: https://doi.org/10.4161/cc.10.17.17181 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Non-hominid TP63 lacks retroviral LTRs but contains a novel conserved upstream exon​
    Beyer, U. & Dobbelstein, M. ​ (2011) 
    Cell Cycle10(12) pp. 1905​-1911​.​ DOI: https://doi.org/10.4161/cc.10.12.15838 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article
    ​ ​Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A​
    Savelyeva, I. & Dobbelstein, M. ​ (2011) 
    Oncogene30(7) pp. 865​-875​.​ DOI: https://doi.org/10.1038/onc.2010.461 
    Details  DOI  PMID  PMC  WoS 
  • 2011 Journal Article | Research Paper
    ​ ​Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart​
    Knöll, R.; Linke, W. A. ; Zou, P.; Miocic, S.; Kostin, S.; Buyandelger, B. & Ku, C.-H. et al.​ (2011) 
    Circulation Research109(7) pp. 758​-U153​.​ DOI: https://doi.org/10.1161/CIRCRESAHA.111.245787 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Conference Abstract
    ​ ​miR-449 induces apoptosis while triggering a stress and DNA damage response​
    Lize, M. ; Herr, C.; Bals, R. & Dobbelstein, M. ​ (2010)
    EJC SUPPLEMENTS8(5) ​21st Meeting of the European-Association-for-Cancer-Research​, Oslo, NORWAY.
    Oxford​: Pergamon-elsevier Science Ltd.
    Details  WoS 
  • 2010 Journal Article
    ​ ​p63 antagonizes Wnt-induced transcription​
    Drewelus, I.; Göpfert, C.; Hippel, C.; Dickmanns, A.; Damianitsch, K.; Pieler, T. & Dobbelstein, M. ​ (2010) 
    Cell Cycle9(3) pp. 580​-587​.​
    Details  PMID  PMC  WoS 
  • 2010 Journal Article | Research Paper
    ​ ​38 miR-449 induces apoptosis while triggering a stress and DNA damage response​
    Lizé, M. ; Herr, C.; Bals, R. & Dobbelstein, M. ​ (2010) 
    European Journal of Cancer : EJC Supplements8(5) pp. 10​.​ DOI: https://doi.org/10.1016/S1359-6349(10)70847-8 
    Details  DOI 
  • 2010 Journal Article | 
    ​ ​E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis​
    Lize, M.; Pilarski, S. & Dobbelstein, M. ​ (2010) 
    Cell Death and Differentiation17(3) pp. 452​-458​.​ DOI: https://doi.org/10.1038/cdd.2009.188 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article
    ​ ​Self-association of adenovirus type 5 E1B-55kDa as well as p53 is essential for their mutual interaction​
    Morawska-Onyszczuk, M.; Bienkowska-Szewczyk, K. & Dobbelstein, M. ​ (2010) 
    Oncogene29(12) pp. 1773​-1786​.​ DOI: https://doi.org/10.1038/onc.2009.461 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article
    ​ ​microRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia​
    Lize, M. ; Herr, C.; Klimke, A.; Bals, R. & Dobbelstein, M. ​ (2010) 
    Cell Cycle9(22) pp. 4579​-4583​.​ DOI: https://doi.org/10.4161/cc.9.22.13870 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | Letter Note | 
    ​ ​Brdm2-an aberrant hypomorphic p63 allele​
    Talos, F.; Wolff, S.; Beyer, U.; Dobbelstein, M.   & Moll, U. M.​ (2010) 
    Cell Death and Differentiation17(1) pp. 184​-186​.​ DOI: https://doi.org/10.1038/cdd.2009.158 
    Details  DOI  PMID  PMC  WoS 
  • 2010 Journal Article | 
    ​ ​p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis​
    Talos, F.; Abraham, A.; Vaseva, A. V.; Holembowski, L. ; Tsirka, S. E.; Scheel, A. & Bode, D. et al.​ (2010) 
    Cell Death and Differentiation17(12) pp. 1816​-1829​.​ DOI: https://doi.org/10.1038/cdd.2010.131 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | Letter Note
    ​ ​Cell cycle arrest or apoptosis by p53 Are microRNAs-192/215 and-34 making the decision?​
    Georges, S. A.; Chau, B. N.; Braun, C. J.; Zhang, X. & Dobbelstein, M. ​ (2009) 
    Cell Cycle8(5) pp. 680​-681​.​
    Details  PMID  PMC  WoS 
  • 2009 Journal Article
    ​ ​Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression​
    Scheel, A. H. J.; Beyer, U.; Agami, R. & Dobbelstein, M. ​ (2009) 
    Cell Cycle8(9) pp. 1426​-1432​.​ DOI: https://doi.org/10.4161/cc.8.9.8324 
    Details  DOI  PMID  PMC  WoS 
  • 2009 Journal Article | 
    ​ ​The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins​
    Wolff, S.; Talos, F.; Palacios, G.; Beyer, U.; Dobbelstein, M.   & Moll, U. M.​ (2009) 
    Cell Death and Differentiation16(8) pp. 1108​-1117​.​ DOI: https://doi.org/10.1038/cdd.2009.25 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | 
    ​ ​NF-Y Dependent Epigenetic Modifications Discriminate between Proliferating and Postmitotic Tissue​
    Gurtner, A.; Fuschi, P.; Magi, F.; Colussi, C.; Gaetano, C.; Dobbelstein, M.   & Sacchi, A. et al.​ (2008) 
    PLoS ONE3(4) art. e2047​.​ DOI: https://doi.org/10.1371/journal.pone.0002047 
    Details  DOI  PMID  PMC 
  • 2008 Journal Article
    ​ ​Specific inhibition of Mdm2-mediated neddylation by Tip60​
    Dohmesen, C.; Koeppel, M. & Dobbelstein, M. ​ (2008) 
    Cell Cycle7(2) pp. 222​-231​.​ DOI: https://doi.org/10.4161/cc.7.2.5185 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | 
    ​ ​BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways​
    Kranz, D.; Dohmesen, C. & Dobbelstein, M. ​ (2008) 
    The Journal of Cell Biology182(1) pp. 197​-213​.​ DOI: https://doi.org/10.1083/jcb.200712014 
    Details  DOI  PMID  PMC  WoS 
  • 2008 Journal Article | 
    ​ ​p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest​
    Braun, C. J.; Zhang, X.; Savelyeva, I.; Wolff, S.; Moll, U. M.; Schepeler, T. & Orntoft, T. F. et al.​ (2008) 
    Cancer Research68(24) pp. 10094​-10104​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-08-1569 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​E1A genes of adenovirus type 2 and type 5 are expressed at different levels​
    Moritz, C. & Dobbelstein, M. ​ (2006) 
    Archives of Virology151(6) pp. 1085​-1092​.​ DOI: https://doi.org/10.1007/s00705-005-0702-y 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Nongenotoxic p53 activation protects cells against S-phase-specific chemotherapy​
    Kranz, D. & Dobbelstein, M. ​ (2006) 
    Cancer Research66(21) pp. 10274​-10280​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-06-1527 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Adenovirus-induced extracellular signal-regulated kinase phosphorylation during the late phase of infection enhances viral protein levels and virus progeny​
    Schumann, M.   & Dobbelstein, M. ​ (2006) 
    Cancer Research66(3) pp. 1282​-1288​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-05-1484 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Dysfunctional p53 deletion mutants in cell lines derived from Hodgkin's lymphoma​
    Feuerborn, A.; Moritz, C.; von Bonin, F.; Dobbelstein, M. ; Truemper, L. H.; Sturzenhofecker, B. & Kube, D.​ (2006) 
    Leukemia & Lymphoma47(9) pp. 1932​-1940​.​ DOI: https://doi.org/10.1080/10428190600667721 
    Details  DOI  PMID  PMC  WoS 
  • 2006 Journal Article
    ​ ​Activating ras mutations fail to ensure efficient replication of adenovirus mutants lacking VA-RNA​
    Schumann, M. & Dobbelstein, M. ​ (2006) 
    Cell Cycle5(3) pp. 315​-321​.​ DOI: https://doi.org/10.4161/cc.5.3.2411 
    Details  DOI  PMID  PMC  WoS 
  • 2005 Journal Article
    ​ ​Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G 2 /M Promoters​
    Imbriano, C.; Gurtner, A.; Cocchiarella, F.; Di Agostino, S.; Basile, V.; Gostissa, M. & Dobbelstein, M.  et al.​ (2005) 
    Molecular and Cellular Biology25(9) pp. 3737​-3751​.​ DOI: https://doi.org/10.1128/MCB.25.9.3737-3751.2005 
    Details  DOI 
  • 2005 Journal Article
    ​ ​Enhanced Cytotoxicity without Internuclear Spread of Adenovirus upon Cell Fusion by Measles Virus Glycoproteins​
    Horn, G. P.; Vongpunsawad, S.; Kornmann, E.; Fritz, B.; Dittmer, D. P.; Cattaneo, R. & Dobbelstein, M. ​ (2005) 
    Journal of Virology79(3) pp. 1911​-1917​.​ DOI: https://doi.org/10.1128/JVI.79.3.1911-1917.2005 
    Details  DOI 
  • 2005 Journal Article
    ​ ​p73-induced apoptosis: A question of compartments and cooperation​
    Dobbelstein, M. ; Strano, S.; Roth, J. & Blandino, G.​ (2005) 
    Biochemical and Biophysical Research Communications331(3) pp. 688​-693​.​ DOI: https://doi.org/10.1016/j.bbrc.2005.03.155 
    Details  DOI 
  • 2004 Journal Article
    ​ ​E1B-55-Kilodalton Protein Is Not Required To Block p53-Induced Transcription during Adenovirus Infection​
    Hobom, U. & Dobbelstein, M. ​ (2004) 
    Journal of Virology78(14) pp. 7685​-7697​.​ DOI: https://doi.org/10.1128/JVI.78.14.7685-7697.2004 
    Details  DOI 
  • 2003 Journal Article
    ​ ​Viruses in therapy—royal road or dead end?​
    Dobbelstein, M. ​ (2003) 
    Virus Research92(2) pp. 219​-221​.​ DOI: https://doi.org/10.1016/S0168-1702(02)00355-6 
    Details  DOI 
  • 2003 Journal Article
    ​ ​Mutual Interference of Adenovirus Infection and myc Expression​
    Löhr, K.; Hartmann, O.; Schäfer, H. & Dobbelstein, M. ​ (2003) 
    Journal of Virology77(14) pp. 7936​-7944​.​ DOI: https://doi.org/10.1128/JVI.77.14.7936-7944.2003 
    Details  DOI 
  • 2003 Journal Article
    ​ ​ΔNp73 can modulate the expression of various genes in a p53-independent fashion​
    Kartasheva, N. N; Lenz-Bauer, C.; Hartmann, O.; Schäfer, H.; Eilers, M. & Dobbelstein, M. ​ (2003) 
    Oncogene22(51) pp. 8246​-8254​.​ DOI: https://doi.org/10.1038/sj.onc.1207138 
    Details  DOI 
  • 2003 Journal Article
    ​ ​Differential regulation of p63 and p73 expression​
    Waltermann, A.; Kartasheva, N. N & Dobbelstein, M. ​ (2003) 
    Oncogene22(36) pp. 5686​-5693​.​ DOI: https://doi.org/10.1038/sj.onc.1206859 
    Details  DOI 
  • 2003 Journal Article
    ​ ​p21/CDKN1A Mediates Negative Regulation of Transcription by p53​
    Löhr, K.; Möritz, C.; Contente, A. & Dobbelstein, M. ​ (2003) 
    Journal of Biological Chemistry278(35) pp. 32507​-32516​.​ DOI: https://doi.org/10.1074/jbc.M212517200 
    Details  DOI 
  • 2002 Journal Article
    ​ ​A polymorphic microsatellite that mediates induction of PIG3 by p53​
    Contente, A.; Dittmer, A.; Koch, M. C.; Roth, J. & Dobbelstein, M. ​ (2002) 
    Nature Genetics30(3) pp. 315​-320​.​ DOI: https://doi.org/10.1038/ng836 
    Details  DOI 
  • 2002 Journal Article
    ​ ​p53 induces the expression of its antagonist p73ΔN, establishing an autoregulatory feedback loop​
    Kartasheva, N. N; Contente, A.; Lenz-Stöppler, C.; Roth, J. & Dobbelstein, M. ​ (2002) 
    Oncogene21(31) pp. 4715​-4727​.​ DOI: https://doi.org/10.1038/sj.onc.1205584 
    Details  DOI 
  • 2002 Journal Article
    ​ ​YB-1 Relocates to the Nucleus in Adenovirus-infected Cells and Facilitates Viral Replication by Inducing E2 Gene Expression through the E2 Late Promoter​
    Holm, P. S.; Bergmann, S.; Jürchott, K.; Lage, H.; Brand, K.; Ladhoff, A. & Mantwill, K. et al.​ (2002) 
    Journal of Biological Chemistry277(12) pp. 10427​-10434​.​ DOI: https://doi.org/10.1074/jbc.M106955200 
    Details  DOI 
  • 2001 Journal Article
    ​ ​Viral and Cellular Factors That Target the Promyelocytic Leukemia Oncogenic Domains Strongly Activate a Glucocorticoid-Responsive Promoter​
    Wienzek, S. & Dobbelstein, M. ​ (2001) 
    Journal of Virology75(11) pp. 5391​-5397​.​ DOI: https://doi.org/10.1128/JVI.75.11.5391-5397.2001 
    Details  DOI 
  • 2000 Journal Article
    ​ ​Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain​
    Roth, J. C.; Koch, P.; Contente, A. & Dobbelstein, M. ​ (2000) 
    Gastroenterology118(4) pp. A665​.​ DOI: https://doi.org/10.1016/S0016-5085(00)84796-4 
    Details  DOI 
  • 2000 Journal Article
    ​ ​The Nuclear Export Signal within the E4orf6 Protein of Adenovirus Type 5 Supports Virus Replication and Cytoplasmic Accumulation of Viral mRNA​
    Weigel, S. & Dobbelstein, M. ​ (2000) 
    Journal of Virology74(2) pp. 764​-772​.​ DOI: https://doi.org/10.1128/JVI.74.2.764-772.2000 
    Details  DOI 
  • 2000 Journal Article
    ​ ​The Nuclear Export Signal within the Adenovirus E4orf6 Protein Contributes to Several Steps in the Viral Life Cycle​
    Dobbelstein, M. ​ (2000) 
    Journal of Virology74(24) pp. 12000​-12001​.​ DOI: https://doi.org/10.1128/JVI.74.24.12000-12001.2000 
    Details  DOI 
  • 2000 Journal Article
    ​ ​Rev Protein of Human Immunodeficiency Virus Type 1 and Cellular Exportin 1 Protein Relocalize Each Other to a Subnucleolar Structure​
    Ristea, S.; Dobbelstein, M.   & Roth, J.​ (2000) 
    AIDS Research and Human Retroviruses16(9) pp. 857​-865​.​ DOI: https://doi.org/10.1089/08892220050042792 
    Details  DOI 
  • 2000 Journal Article
    ​ ​E1B 55-Kilodalton Oncoproteins of Adenovirus Types 5 and 12 Inactivate and Relocalize p53, but Not p51 or p73, and Cooperate with E4orf6 Proteins To Destabilize p53​
    Wienzek, S.; Roth, J. & Dobbelstein, M. ​ (2000) 
    Journal of Virology74(1) pp. 193​-202​.​ DOI: https://doi.org/10.1128/JVI.74.1.193-202.2000 
    Details  DOI 
  • 2000 Journal Article
    ​ ​Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain​
    Roth, J.; Koch, P.; Contente, A. & Dobbelstein, M. ​ (2000) 
    Oncogene19(14) pp. 1834​-1842​.​ DOI: https://doi.org/10.1038/sj.onc.1203500 
    Details  DOI 
  • 1999 Journal Article
    ​ ​Failure of viral oncoproteins to target the p53-homologue p51A​
    Roth, J. & Dobbelstein, M. ​ (1999) 
    Journal of General Virology80(12) pp. 3251​-3255​.​ DOI: https://doi.org/10.1099/0022-1317-80-12-3251 
    Details  DOI 
  • 1999 Journal Article
    ​ ​Inactivation of the p53-homologue p73 by the mdm2-oncoprotein​
    Dobbelstein, M. ; Wienzek, S.; König, C. & Roth, J.​ (1999) 
    Oncogene18(12) pp. 2101​-2106​.​ DOI: https://doi.org/10.1038/sj.onc.1202512 
    Details  DOI 
  • 1998 Journal Article
    ​ ​Inactivation of p53 but Not p73 by Adenovirus Type 5 E1B 55-Kilodalton and E4 34-Kilodalton Oncoproteins​
    Roth, J.; König, C.; Wienzek, S.; Weigel, S.; Ristea, S. & Dobbelstein, M. ​ (1998) 
    Journal of Virology72(11) pp. 8510​-8516​.​ DOI: https://doi.org/10.1128/JVI.72.11.8510-8516.1998 
    Details  DOI 
  • 1998 Journal Article
    ​ ​The large T antigen of simian virus 40 binds and inactivates p53 but not p73.​
    Dobbelstein, M.   & Roth, J.​ (1998) 
    Journal of General Virology79(12) pp. 3079​-3083​.​ DOI: https://doi.org/10.1099/0022-1317-79-12-3079 
    Details  DOI 
  • 1998 Journal Article
    ​ ​Nucleo-cytoplasmic shuttling of the HDM2 oncoprotein regulates the levels of P53 protein VIA a pathway USED by the human immunodeficiency virus REV protein​
    Roth, J.; Dobbelstein, M. ; Freedman, D.; Shenk, T. & Levine, A.​ (1998) 
    Gastroenterology114 pp. A669​.​ DOI: https://doi.org/10.1016/S0016-5085(98)82742-X 
    Details  DOI 
  • 1997 Journal Article
    ​ ​Export of hepatitis B virus RNA on a Rev-like pathway: inhibition by the regenerating liver inhibitory factor IkappaB alpha​
    Roth, J. & Dobbelstein, M. ​ (1997) 
    Journal of Virology71(11) pp. 8933​-8939​.​ DOI: https://doi.org/10.1128/jvi.71.11.8933-8939.1997 
    Details  DOI 
  • 1997 Journal Article
    ​ ​Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence​
    Dobbelstein, M. ​ (1997) 
    The EMBO Journal16(14) pp. 4276​-4284​.​ DOI: https://doi.org/10.1093/emboj/16.14.4276 
    Details  DOI 
  • 1996 Journal Article
    ​ ​The MDM2 Oncoprotein Binds Specifically to RNA through its RING Finger Domain​
    Elenbaas, B.; Dobbelstein, M. ; Roth, J.; Shenk, T. & Levine, A. J.​ (1996) 
    Molecular Medicine2(4) pp. 439​-451​.​ DOI: https://doi.org/10.1007/BF03401903 
    Details  DOI 
  • 1996 Journal Article
    ​ ​Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product​
    Dobbelstein, M.   & Shenk, T.​ (1996) 
    Journal of Virology70(9) pp. 6479​-6485​.​ DOI: https://doi.org/10.1128/jvi.70.9.6479-6485.1996 
    Details  DOI 
  • 1995 Journal Article
    ​ ​In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA libraries​
    Dobbelstein, M.   & Shenk, T.​ (1995) 
    Journal of Virology69(12) pp. 8027​-8034​.​ DOI: https://doi.org/10.1128/jvi.69.12.8027-8034.1995 
    Details  DOI 

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