Prof. Dr. Johannes Kornhuber

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  • 2022 | Journal Article | 
    ​ ​A Comparison of Operational Definitions for Mild Cognitive Impairment​
    Polcher, A.; Wolfsgruber, S.; Peters, O.; Frölich, L.; Wiltfang, J. ; Kornhuber, J.   & Hüll, M. et al.​ (2022) 
    Journal of Alzheimer's Disease, 88(4) pp. 1663​-1678​.​ DOI: https://doi.org/10.3233/JAD-215548 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression​
    Hellmann-Regen, J.; Clemens, V.; Grözinger, M.; Kornhuber, J. ; Reif, A.; Prvulovic, D. & Goya-Maldonado, R.  et al.​ (2022) 
    JAMA Network Open, 5(9) art. e2230367​.​ DOI: https://doi.org/10.1001/jamanetworkopen.2022.30367 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells​
    Carpinteiro, A.; Gripp, B.; Hoffmann, M.; Pöhlmann, S. ; Hoertel, N.; Edwards, M. J. & Kamler, M. et al.​ (2021) 
    Journal of Biological Chemistry, 296 art. S0021925821004907​.​ DOI: https://doi.org/10.1016/j.jbc.2021.100701 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Cognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments​
    Ophey, A.; Wolfsgruber, S.; Roeske, S.; Polcher, A.; Spottke, A.; Frölich, L. & Hüll, M. et al.​ (2021) 
    Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 13(1).​ DOI: https://doi.org/10.1002/dad2.12223 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes​
    Oberstein, T. J.; Utz, J.; Spitzer, P.; Klafki, H. W. ; Wiltfang, J. ; Lewczuk, P.   & Kornhuber, J.  et al.​ (2021) 
    Frontiers in Molecular Neuroscience, 13.​ DOI: https://doi.org/10.3389/fnmol.2020.615740 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer’s Disease Dementia via Lead-Lag Analysis​
    Fuentes, M.; Klostermann, A.; Kleineidam, L.; Bauer, C.; Schuchhardt, J.; Maier, W. & Jessen, F. et al.​ (2020) 
    Journal of Alzheimer's Disease, 76(3) pp. 1005​-1015​.​ DOI: https://doi.org/10.3233/JAD-200230 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Bupropion for the Treatment of Apathy in Alzheimer Disease​
    Maier, F.; Spottke, A.; Bach, J.-P.; Bartels, C. ; Buerger, K.; Dodel, R. & Fellgiebel, A. et al.​ (2020) 
    JAMA Network Open, 3(5) pp. e206027​.​ DOI: https://doi.org/10.1001/jamanetworkopen.2020.6027 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly​
    Rhein, C.; Mühle, C.; Lenz, B.; Richter-Schmidinger, T.; Kogias, G.; Boix, F. & Lourdusamy, A. et al.​ (2020) 
    Brain Research Bulletin, 161 pp. 13​-20​.​ DOI: https://doi.org/10.1016/j.brainresbull.2020.05.001 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment​
    Kleineidam, L.; Chouraki, V.; Próchnicki, T.; van der Lee, S. J.; Madrid-Márquez, L.; Wagner-Thelen, H. & Karaca, I. et al.​ (2020) 
    Acta Neuropathologica, 139(6) pp. 1025​-1044​.​ DOI: https://doi.org/10.1007/s00401-020-02138-6 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study​
    van Maurik, I. S; Vos, S. J; Bos, I.; Bouwman, F. H; Teunissen, C. E; Scheltens, P. & Barkhof, F. et al.​ (2019) 
    The Lancet Neurology, 18(11) pp. 1034​-1044​.​ DOI: https://doi.org/10.1016/S1474-4422(19)30283-2 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging​
    Albrecht, F.; Mueller, K.; Ballarini, T.; Lampe, L.; Diehl-Schmid, J.; Fassbender, K. & Fliessbach, K. et al.​ (2019) 
    Cortex, 117 pp. 33​-40​.​ DOI: https://doi.org/10.1016/j.cortex.2019.02.015 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​A combined miRNA–piRNA signature to detect Alzheimer’s disease​
    Jain, G.; Stuendl, A.; Rao, P.; Berulava, T.; Pena Centeno, T.; Kaurani, L.   & Burkhardt, S.  et al.​ (2019) 
    Translational Psychiatry, 9(1).​ DOI: https://doi.org/10.1038/s41398-019-0579-2 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​
    Lewczuk, P. ; Riederer, P.; O’Bryant, S. E.; Verbeek, M. M.; Dubois, B.; Visser, P. J. & Jellinger, K. A. et al.​ (2018) 
    The World Journal of Biological Psychiatry, 19(4) pp. 244​-328​.​ DOI: https://doi.org/10.1080/15622975.2017.1375556 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Serum neurofilament light chain in behavioral variant frontotemporal dementia​
    Steinacker, P. ; Anderl-Straub, S.; Diehl-Schmid, J.; Semler, E.; Uttner, I.; von Arnim, C. A. & Barthel, H. et al.​ (2018) 
    Neurology, 91(15) pp. e1390​-e1401​.​ DOI: https://doi.org/10.1212/WNL.0000000000006318 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease​
    Mattsson, N.; Groot, C.; Jansen, W. J.; Landau, S. M.; Villemagne, V. L.; Engelborghs, S. & Mintun, M. M. et al.​ (2018) 
    Alzheimer's & Dementia, 14(7) pp. 913​-924​.​ DOI: https://doi.org/10.1016/j.jalz.2018.02.009 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes​
    Espinosa, A.; Hernández-Olasagarre, B.; Moreno-Grau, S.; Kleineidam, L.; Heilmann-Heimbach, S.; Hernández, I. & Wolfsgruber, S. et al.​ (2018) 
    Frontiers in Aging Neuroscience, 10.​ DOI: https://doi.org/10.3389/fnagi.2018.00340 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​A Modified Reading the Mind in the Eyes Test Predicts Behavioral Variant Frontotemporal Dementia Better Than Executive Function Tests​
    Schroeter, M. L.; Pawelke, S.; Bisenius, S.; Kynast, J.; Schuemberg, K.; Polyakova, M. & Anderl-Straub, S. et al.​ (2018) 
    Frontiers in Aging Neuroscience, 10.​ DOI: https://doi.org/10.3389/fnagi.2018.00011 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls​
    Denk, J.; Oberhauser, F.; Kornhuber, J. ; Wiltfang, J. ; Fassbender, K.; Schroeter, M. L. & Volk, A. E. et al.​ (2018) 
    PLoS One, 13(5) pp. e0197329​.​ DOI: https://doi.org/10.1371/journal.pone.0197329 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​A language-based sum score for the course and therapeutic intervention in primary progressive aphasia​
    Semler, E.; Anderl-Straub, S.; Uttner, I.; Diehl-Schmid, J.; Danek, A.; Einsiedler, B. & Fassbender, K. et al.​ (2018) 
    Alzheimer's Research & Therapy, 10(1).​ DOI: https://doi.org/10.1186/s13195-018-0345-3 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​The frequency and influence of dementia risk factors in prodromal Alzheimer's disease​
    Bos, I.; Vos, S. J.; Frölich, L.; Kornhuber, J. ; Wiltfang, J. ; Maier, W. & Peters, O. et al.​ (2017) 
    Neurobiology of Aging, 56 pp. 33​-40​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2017.03.034 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia​
    Frölich, L.; Peters, O.; Lewczuk, P. ; Gruber, O. ; Teipel, S. J.; Gertz, H. J. & Jahn, H. et al.​ (2017) 
    Alzheimer's Research & Therapy, 9(1) art. 84​.​ DOI: https://doi.org/10.1186/s13195-017-0301-7 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms​
    Schmitt, A.; Martins-de-Souza, D.; Akbarian, S.; Cassoli, J. S.; Ehrenreich, H. ; Fischer, A.   & Fonteh, A. et al.​ (2017) 
    The World journal of Biological Psychiatry, 18(5) pp. 330​-356​.​ DOI: https://doi.org/10.1080/15622975.2016.1224929 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment​
    Wolfsgruber, S.; Polcher, A.; Koppara, A.; Kleineidam, L.; Frölich, L.; Peters, O. & Hüll, M. et al.​ (2017) 
    Journal of Alzheimer's Disease, 58(3) pp. 939​-950​.​ DOI: https://doi.org/10.3233/JAD-161252 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article
    ​ ​Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias​
    Steinacker, P. ; Semler, E.; Anderl-Straub, S.; Diehl-Schmid, J.; Schroeter, M. L.; Uttner, I. & Foerstl, H. et al.​ (2017) 
    Neurology, 88(10) pp. 961​-969​.​ DOI: https://doi.org/10.1212/WNL.0000000000003688 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment​
    Bey, K.; Wolfsgruber, S.; Karaca, I.; Wagner, H.; Lardenoije, R.; Becker, J. & Milz, E. et al.​ (2016) 
    Epigenomics, 8(5) pp. 593​-598​.​ DOI: https://doi.org/10.2217/epi-2015-0014 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics​
    Lelental, N.; Brandner, S.; Kofanova, O.; Blennow, K.; Zetterberg, H.; Andreasson, U. & Engelborghs, S. et al.​ (2016) 
    Journal of Alzheimer's Disease, 52(1) pp. 51​-64​.​ DOI: https://doi.org/10.3233/jad-150883 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment​
    Koppara, A.; Wolfsgruber, S.; Kleineidam, L.; Schmidtke, K.; Frölich, L.; Kurz, A. & Schulz, S. et al.​ (2016) 
    Journal of Alzheimer's Disease, 49(2) pp. 547​-560​.​ DOI: https://doi.org/10.3233/jad-150257 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment​
    Louwersheimer, E.; Wolfsgruber, S.; Espinosa, A.; Lacour, A.; Heilmann-Heimbach, S.; Alegret, M. & Hernández, I. et al.​ (2016) 
    Alzheimer's & Dementia, 12(8) pp. 872​-881​.​ DOI: https://doi.org/10.1016/j.jalz.2016.01.006 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment​
    Lacour, A.; Espinosa, A.; Louwersheimer, E.; Heilmann, S.; Hernández, I.; Wolfsgruber, S. & Fernández, V. et al.​ (2016) 
    Molecular Psychiatry, 22(1) pp. 153​-160​.​ DOI: https://doi.org/10.1038/mp.2016.18 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Das Kompetenznetz Demenzen: ​Erfolge und Ausblicke​
    Peters, O.; Heuser, I.; Frölich, L.; Rüther, E. ; Rienhoff, O. ; Kornhuber, J.   & Wiltfang, J.  et al.​ (2016) 
    Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 59(4) pp. 438​-443​.​ DOI: https://doi.org/10.1007/s00103-016-2314-y 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | 
    ​ ​Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia​
    Teipel, S. J.; Raiser, T.; Riedl, L.; Riederer, I.; Schroeter, M. L.; Bisenius, S. & Schneider, A.  et al.​ (2016) 
    Cortex, 83 pp. 124​-135​.​ DOI: https://doi.org/10.1016/j.cortex.2016.07.004 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article
    ​ ​Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer’s Disease in Pre-Dementia Subjects​
    Lewczuk, P. ; Kornhuber, J. ; Toledo, J. B.; Trojanowski, J. Q.; Knapik-Czajka, M.; Peters, O. & Wiltfang, J.  et al.​ (2015) 
    Journal of Alzheimer's Disease, 48(2) pp. 433​-441​.​ DOI: https://doi.org/10.3233/jad-150342 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage​
    Vos, S. J. B.; Verhey, F. R. J.; Frölich, L.; Kornhuber, J. ; Wiltfang, J. ; Maier, W. & Peters, O. et al.​ (2015) 
    Brain, 138(5) pp. 1327​-1338​.​ DOI: https://doi.org/10.1093/brain/awv029 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI​
    Wolfsgruber, S.; Jessen, F.; Koppara, A.; Kleineidam, L.; Schmidtke, K.; Frölich, L. & Kurz, A. et al.​ (2015) 
    Neurology, 84(12) pp. 1261​-1268​.​ DOI: https://doi.org/10.1212/wnl.0000000000001399 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​PLD3 in non-familial Alzheimer's disease​
    Heilmann, S.; Drichel, D.; Clarimon, J.; Fernández, V.; Lacour, A.; Wagner, H. & Thelen, M. et al.​ (2015) 
    Nature, 520(7545) pp. E3​-E5​.​ DOI: https://doi.org/10.1038/nature14039 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study​
    Morgen, K.; Schneider, M.; Frölich, L.; Tost, H.; Plichta, M. M.; Kölsch, H. & Rakebrandt, F.  et al.​ (2015) 
    Alzheimer's Research & Therapy, 7(1).​ DOI: https://doi.org/10.1186/s13195-015-0111-8 
    ​Details  DOI 
  • 2015 | Journal Article
    ​ ​Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type​
    Popp, J.; Wolfsgruber, S.; Heuser, I.; Peters, O.; Hüll, M.; Schröder, J. & Möller, H.-J. et al.​ (2015) 
    Neurobiology of Aging, 36(2) pp. 601​-607​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2014.10.031 
    ​Details  DOI  PMID  PMC 
  • 2014 | Journal Article
    ​ ​The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease​
    Louwersheimer, E.; Ramirez, A.; Cruchaga, C.; Becker, T.; Kornhuber, J. ; Peters, O. & Heilmann, S. et al.​ (2014) 
    Neurobiology of Aging, 36(3) pp. 1605.e13​-1605.e20​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2014.12.007 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease​
    Ramirez, A.; van der Flier, W. M.; Herold, C.; Ramonet, D.; Heilmann, S.; Lewczuk, P.   & Popp, J. et al.​ (2014) 
    Human Molecular Genetics, 23(24) pp. 6644​-6658​.​ DOI: https://doi.org/10.1093/hmg/ddu372 
    ​Details  DOI 
  • 2014 | Journal Article
    ​ ​Persistence of Haloperidol in Human Brain Tissue​
    Kornhuber, J. ; Schultz, A.; Wiltfang, J. ; Meineke, I.; Gleiter, C. H. ; Zöchling, R. & Boissl, K.-W. et al.​ (2014) 
    The American Journal of Psychiatry, 156(6) pp. 885​-890​.​ DOI: https://doi.org/10.1176/ajp.156.6.885 
    ​Details  DOI 
  • 2014 | Journal Article | 
    ​ ​Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides​
    Oberstein, T. J.; Spitzer, P.; Klafki, H.-W. ; Linning, P.; Neff, F.; Knölker, H.-J. & Lewczuk, P.  et al.​ (2014) 
    Neurobiology of Disease, 73 pp. 24​-35​.​ DOI: https://doi.org/10.1016/j.nbd.2014.08.031 
    ​Details  DOI 
  • 2012 | Book Chapter
    ​ ​The role of glutamate in dementia​
    Kornhuber, J.  & Wiltfang, J. ​ (2012)
    In:​Jellinger, Kurt; Fazekas, F.; Windisch, Manfred​ (Eds.), Ageing and Dementia. ​Vienna: ​Springer. DOI: https://doi.org/10.1007/978-3-7091-6467-9_24 
    ​Details  DOI 
  • 2012 | Journal Article
    ​ ​Decreased  β-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease​
    Otto, M. ; Esselmann, H. ; Schulz-Schaeffer, W. ; Neumann, M.; Schröter, A. ; Ratzka, P.   & Cepek, L.  et al.​ (2012) 
    Neurology, 54(5) pp. 1099​-1102​.​ DOI: https://doi.org/10.1212/wnl.54.5.1099 
    ​Details  DOI 
  • 2012 | Journal Article | Research Paper
    ​ ​Use-Dependent Inhibition of Synaptic Transmission by the Secretion of Intravesicularly Accumulated Antipsychotic Drugs​
    Tischbirek, C. H.; Wenzel, E. M.; Zheng, F.; Huth, T.; Amato, D.; Trapp, S. & Denker, A. et al.​ (2012) 
    Neuron, 74(5) pp. 830​-844​.​ DOI: https://doi.org/10.1016/j.neuron.2012.04.019 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Book Chapter
    ​ ​Neurotransmitterveränderungen bei der Alzheimer Demenz​
    Kornhuber, J. ; Gundacker, I.; Maler, M. ; Otto, M.  & Wiltfang, J. ​ (2011)
    In:​Förstl, Hans; Bickel, Horst; Kurz, Alexander​ (Eds.), Alzheimer Demenz - Grundlagen, Klinik und Therapie. ​Berlin, Heidelberg: ​Springer. DOI: https://doi.org/10.1007/978-3-642-60228-3_5 
    ​Details  DOI 
  • 2011 | Journal Article | Research Paper
    ​ ​Systematic Heterogeneity of Fractional Vesicle Pool Sizes and Release Rates of Hippocampal Synapses​
    Welzel, O.; Henkel, A. W.; Stroebel, A. M.; Jung, J.; Tischbirek, C. H.; Ebert, K. & Kornhuber, J.  et al.​ (2011) 
    Biophysical Journal, 100(3) pp. 593​-601​.​ DOI: https://doi.org/10.1016/j.bpj.2010.12.3706 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Short-term influence of elevation of plasma homocysteine levels on cognitive function in young healthy adults​
    Alexopoulos, P.; Lehrl, S.; Richter-Schmidinger, T.; Kreusslein, A.; Hauenstein, T.; Bayerl, F. & Jung, P. et al.​ (2010) 
    The Journal of Nutrition, Health & Aging, 14(4) pp. 283​-287​.​ DOI: https://doi.org/10.1007/s12603-010-0062-5 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​Validation of the German Revised Addenbrooke’s Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer’s Disease and Frontotemporal Lobar Degeneration​
    Alexopoulos, P.; Ebert, A. ; Richter-Schmidinger, T.; Schöll, E.; Natale, B.; Aguilar, C. A. & Gourzis, P. et al.​ (2010) 
    Dementia and Geriatric Cognitive Disorders, 29(5) pp. 448​-456​.​ DOI: https://doi.org/10.1159/000312685 
    ​Details  DOI 
  • 2010 | Journal Article
    ​ ​Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults​
    Richter-Schmidinger, T.; Alexopoulos, P.; Horn, M.; Maus, S.; Reichel, M.; Rhein, C. & Lewczuk, P.  et al.​ (2010) 
    Journal of Neural Transmission, 118(2) pp. 249​-257​.​ DOI: https://doi.org/10.1007/s00702-010-0539-8 
    ​Details  DOI 
  • 2009 | Journal Article
    ​ ​PLASMA HOMOCYSTEINE AND CEREBROSPINAL FLUID NEURODEGENERATION BIOMARKERS IN MILD COGNITIVE IMPAIRMENT AND DEMENTIA​
    Alexopoulos, P.; Günther, F.; Popp, J.; Jessen, F.; Peters, O.; Wolf, S. & Kneib, T.  et al.​ (2009) 
    Journal of the American Geriatrics Society, 57(4) pp. 737​-739​.​ DOI: https://doi.org/10.1111/j.1532-5415.2009.02212.x 
    ​Details  DOI 
  • 2008 | Journal Article
    ​ ​Neuronale Kaliumkanalöffnung durch Flupirtin: ​Opening of Neuronal K+ Channels by Flupirtine​
    Kornhuber, J. ; Maler, M. ; Wiltfang, J. ; Bleich, S. ; Degner, D.   & Rüther, E. ​ (2008) 
    Fortschritte der Neurologie · Psychiatrie, 67(10) pp. 466​-475​.​ DOI: https://doi.org/10.1055/s-2007-994997 
    ​Details  DOI 
  • 2004 | Journal Article
    ​ ​Lithium Decreases Secretion of Aβ1–42 and C-Truncated Species Aβ1–37/38/39/40 in Chicken Telencephalic Cultures but Specifically Increases Intracellular Aβ1–38​
    Esselmann, H. ; Maler, J. M. ; Kunz, N. ; Otto, M. ; Paul, S. ; Lewczuk, P.   & Rüther, E.  et al.​ (2004) 
    Neurodegenerative Diseases, 1(4-5) pp. 236​-241​.​ DOI: https://doi.org/10.1159/000080992 
    ​Details  DOI 
  • 2004 | Journal Article
    ​ ​Electrophoretic separation of amyloid β peptides in plasma​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Paul, S.; Svitek, J.; Miertschischk, J. & Meyrer, R. et al.​ (2004) 
    ELECTROPHORESIS, 25(20) pp. 3336​-3343​.​ DOI: https://doi.org/10.1002/elps.200406068 
    ​Details  DOI 
  • 2004 | Journal Article
    ​ ​Cerebrospinal fluid amyloidβ peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloidβ peptides​
    Bibl, M. ; Esselmann, H. ; Otto, M. ; Lewczuk, P. ; Cepek, L. ; Rüther, E.   & Kornhuber, J.  et al.​ (2004) 
    ELECTROPHORESIS, 25(17) pp. 2912​-2918​.​ DOI: https://doi.org/10.1002/elps.200305992 
    ​Details  DOI 
  • 2004 | Journal Article
    ​ ​Tau Protein Phosphorylated at Threonine 181 in CSF as a Neurochemical Biomarker in Alzheimer's Disease: ​Original Data and Review of the Literature​
    Lewczuk, P. ; Esselmann, H. ; Bibl, M. ; Beck, G.; Maler, J. M. ; Otto, M.   & Kornhuber, J.  et al.​ (2004) 
    Journal of Molecular Neuroscience, 23(1-2) pp. 115​-122​.​ DOI: https://doi.org/10.1385/jmn:23:1-2:115 
    ​Details  DOI  PMID  PMC 
  • 2004 | Journal Article
    ​ ​Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease​
    Lewczuk, P. ; Esselmann, H. ; Groemer, T. W.; Bibl, M. ; Maler, J. M. ; Steinacker, P.   & Otto, M.  et al.​ (2004) 
    Biological Psychiatry, 55(5) pp. 524​-530​.​ DOI: https://doi.org/10.1016/j.biopsych.2003.10.014 
    ​Details  DOI  PMID  PMC 
  • 2003 | Journal Article
    ​ ​Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation​
    Wiltfang, J. ; Esselmann, H. ; Bibl, M. ; Smirnov, A. ; Otto, M. ; Paul, S.   & Schmidt, B.  et al.​ (2003) 
    Journal of Neurochemistry, 81(3) pp. 481​-496​.​ DOI: https://doi.org/10.1046/j.1471-4159.2002.00818.x 
    ​Details  DOI 
  • 2003 | Journal Article
    ​ ​Homocysteine induces cell death of rat astrocytes in vitro​
    Maler, J. M. ; Seifert, W.; Hüther, G. ; Wiltfang, J. ; Rüther, E. ; Kornhuber, J.   & Bleich, S. ​ (2003) 
    Neuroscience Letters, 347(2) pp. 85​-88​.​ DOI: https://doi.org/10.1016/s0304-3940(03)00655-4 
    ​Details  DOI  PMID  PMC 
  • 2002 | Journal Article
    ​ ​Glutamaterge Neurotransmission bei Schizophrenien​
    Bleich, S. ; Bleich, K.; Wiltfang, J. ; Maler, J. M.   & Kornhuber, J. ​ (2002) 
    Fortschritte der Neurologie · Psychiatrie, 69(SH2) pp. 56​-61​.​ DOI: https://doi.org/10.1055/s-2001-16531 
    ​Details  DOI 
  • 2002 | Journal Article
    ​ ​Flupirtine shows functional NMDA receptor antagonism by enhancing Mg 2+ block via activation of voltage independent potassium channels​
    Kornhuber, J. ; Bleich, S. ; Wiltfang, J. ; Maler, M. & Parsons, C. G.​ (2002) 
    Journal of Neural Transmission, 106(9) pp. 857​-867​.​ DOI: https://doi.org/10.1007/s007020050206 
    ​Details  DOI 
  • 2001 | Journal Article
    ​ ​Neue Behandlungsparadigmen der Demenz. Rechtzeitig erkennen - und dann?​
    Demling, J. H.; Wiltfang, J.   & Kornhuber, J. ​ (2001) 
    DNP - Neurologe und Psychiater, 4.​
    ​Details 
  • 2001 | Journal Article
    ​ ​Molecular Biology of Alzheimer’s Dementia and Its Clinical Relevance to Early Diagnosis and New Therapeutic Strategies​
    Wiltfang, J. ; Esselmann, H. ; Maler, J. M. ; Bleich, S. ; Hüther, G.   & Kornhuber, J. ​ (2001) 
    Gerontology, 47(2) pp. 65​-71​.​ DOI: https://doi.org/10.1159/000052775 
    ​Details  DOI  PMID  PMC 
  • 2000 | Journal Article
    ​ ​Creutzfeldt-Jakob disease and oxidative stress​
    Bleich, S. ; Kropp, S. ; Degner, D. ; Zerr, I. ; Pilz, J. ; Gleiter, C. H.   & Otto, M.  et al.​ (2000) 
    Acta Neurologica Scandinavica, 101(5) pp. 332​-334​.​ DOI: https://doi.org/10.1034/j.1600-0404.2000.9s290a.x 
    ​Details  DOI  PMID  PMC 
  • 2000 | Journal Article
    ​ ​Elevated Homocysteine Levels in Alcohol Withdrawal​
    Bleich, S. ; Degner, D. ; Wiltfang, J. ; Maler, J. M. ; Niedmann, P. ; Cohrs, S.   & Mangholz, A.  et al.​ (2000) 
    Alcohol and Alcoholism, 35(4) pp. 351​-354​.​ DOI: https://doi.org/10.1093/alcalc/35.4.351 
    ​Details  DOI  PMID  PMC 
  • 1999 | Book Chapter
    ​ ​Amantadin​
    Kornhuber, J.  & Wiltfang, J. ​ (1999)
    In:​von Riederer, P.; Laux, G.; Poldinger, W.​ (Eds.), Neuro-Psychopharmaka - Ein Therapie-Handbuch pp. 261​-286. (2. ed., Vol. 5). ​Wien: ​Springer.
    ​Details 
  • 1999 | Journal Article
    ​ ​Der NMDA-Rezeptor: ein Ionenkanal mit zwei Gesichtern​
    Esselmann, H. ; Wiltfang, J.   & Kornhuber, J. ​ (1999) 
    Neurotransmitter, 2.​
    ​Details 
  • 1999 | Journal Article
    ​ ​Tau Protein: Ein potentieller biologischer Indikator zur Früherkennung der Alzheimer-Krankheit: ​Anmerkung zur Arbeit von K. Buch et al. Nervenarzt (1998) 69: 379–385​
    Otto, M. ; Wiltfang, J. ; Poser, S.   & Kornhuber, J. ​ (1999) 
    Der Nervenarzt, 70(7) pp. 668​-670​.​ DOI: https://doi.org/10.1007/s001150050494 
    ​Details  DOI 
  • 1999 | Journal Article
    ​ ​Oxidative stress and an altered methionine metabolism in alcoholism​
    Bleich, S. ; Spilker, K. ; Kurth, C. ; Degner, D. ; Quintela-Schneider, M. ; Javaheripour, K.   & Rüther, E.  et al.​ (1999) 
    Neuroscience Letters, 293(3) pp. 171​-174​.​ DOI: https://doi.org/10.1016/s0304-3940(00)01505-6 
    ​Details  DOI  PMID  PMC 
  • 1999 | Journal Article
    ​ ​Isoform Pattern of 14-3-3 Proteins in the Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease​
    Wiltfang, J. ; Otto, M. ; Baxter, H. C.; Bodemer, M. ; Steinacker, P. ; Bahn, E.   & Zerr, I.  et al.​ (1999) 
    Journal of Neurochemistry, 73(6) pp. 2485​-2490​.​ DOI: https://doi.org/10.1046/j.1471-4159.1999.0732485.x 
    ​Details  DOI  PMID  PMC 
  • 1999 | Journal Article
    ​ ​The N-methyl-D-aspartate receptor channel blocker amantadine does not cause histopathological alterations in human brain tissue​
    Kornhuber, J. ; Jellinger, K.; Wiltfang, J. ; Leblhuber, F. & Riederer, P.​ (1999) 
    Acta Neuropathologica, 98(1) pp. 85​-90​.​ DOI: https://doi.org/10.1007/s004010051054 
    ​Details  DOI  PMID  PMC 
  • 1998 | Journal Article
    ​ ​Was wird aus Gedächtnisstörungen​
    Kornhuber, J. ; Wiltfang, J. ; Tumani, H.   & Rüther, E. ​ (1998) 
    Psycho, 12.​
    ​Details 
  • 1998 | Journal Article
    ​ ​Psychiatric Aspects of Portal-Systemic Encephalopathy​
    Wiltfang, J. ; Nolte, W. ; Weißenborn, K.; Kornhuber, J.   & Rüther, E. ​ (1998) 
    Metabolic Brain Disease, 13(4) pp. 379​-389​.​ DOI: https://doi.org/10.1023/a:1020697127718 
    ​Details  DOI 
  • 1998 | Journal Article
    ​ ​Labordiagnostik der Alzheimer-Demenz​
    Wiltfang, J. ; Otto, M.   & Kornhuber, J. ​ (1998) 
    Psycho, 12.​
    ​Details 

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